YPT31/YER031C Protein Information

Standard Name	Ypt31p 1
Systematic Name	Yer031cp
Alias	Ypt8p 2
ORF Classification	Verified
Description	Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication (1, 3, 4, 5, 6)
Name Description	Yeast Protein Two 1

Experimental Data
Molecules/cell	5960 7

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	223
Molecular Weight (Da)	24,469
Isoelectric Point (pI)	4.81

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ypt31p (InterPro)
Physical Interactions	There are 56 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000052FA0 \| P38555 MIPS: YER031C NCBI: 187609401 \| 425713 \| 586807 \| 603623 \| 6320869 \| 927541 \| NP_010948.1 GenBank/EMBL/DDBJ: DAA07684.1 \| L17070 \| U18778 \| X72833

Amino Acid Sequence (or in FASTA format)
1 MSSEDYGYDY DLLFKIVLIG DSGVGKSNLL SRFTKNEFNM DSKSTIGVEF 51 ATRTLEIDGK RIKAQIWDTA GQERYRAITS AYYRGAVGAL IVYDISKSSS 101 YENCNHWLSE LRENADDNVA VGLIGNKSDL AHLRAVPTEE SKTFAQENQL 151 LFTETSALNS ENVDKAFEEL INTIYQKVSK HQMDLGDSSA NGNANGASAP 201 NGPTISLTPT PNENKKANGN NCC*

Amino Acid Sequence (or in FASTA format)

       1  MSSEDYGYDY DLLFKIVLIG DSGVGKSNLL SRFTKNEFNM DSKSTIGVEF
      51  ATRTLEIDGK RIKAQIWDTA GQERYRAITS AYYRGAVGAL IVYDISKSSS
     101  YENCNHWLSE LRENADDNVA VGLIGNKSDL AHLRAVPTEE SKTFAQENQL
     151  LFTETSALNS ENVDKAFEEL INTIYQKVSK HQMDLGDSSA NGNANGASAP
     201  NGPTISLTPT PNENKKANGN NCC*

external links for Ypt31p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
YGOB	CYC2008 (complexes)	Pfam domains
YOGY	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Ypt31p

1)	Benli M, et al. (1996) Two GTPase isoforms, Ypt31p and Ypt32p, are essential for Golgi function in yeast. EMBO J 15(23):6460-75
2)	Lai MH, et al. (1994) Identification of a gene encoding a new Ypt/Rab-like monomeric G-protein in Saccharomyces cerevisiae. Yeast 10(3):399-402
3)	Jedd G, et al. (1997) Two new Ypt GTPases are required for exit from the yeast trans-Golgi compartment. J Cell Biol 137(3):563-80
4)	Lazar T, et al. (1997) Vesicular transport: how many Ypt/Rab-GTPases make a eukaryotic cell? Trends Biochem Sci 22(12):468-72
5)	Wang W and Ferro-Novick S (2002) A Ypt32p exchange factor is a putative effector of Ypt1p. Mol Biol Cell 13(9):3336-43
6)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
7)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41