BIM1/YER016W Protein Information

Standard Name	Bim1p 1
Systematic Name	Yer016wp
Alias	Yeb1p
ORF Classification	Verified
Description	Microtubule-binding protein that together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally (2) Also known as: EB1 3
Name Description	BInding to Microtubules 1

Experimental Data
Molecules/cell	3630 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	344
Molecular Weight (Da)	38,361
Isoelectric Point (pI)	5.16

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Bim1p (InterPro)
Physical Interactions	There are 72 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012693D \| P40013 MIPS: YER016W NCBI: 158430240 \| 383875739 \| 383875740 \| 603608 \| 6320853 \| 731441 \| NP_010932.1 GenBank/EMBL/DDBJ: DAA07668.1 \| U18778

Amino Acid Sequence (or in FASTA format)
1 MSAGIGESRT ELLTWLNGLL NLNYKKIEEC GTGAAYCQIM DSIYGDLPMN 51 RVKFNATAEY EFQTNYKILQ SCFSRHGIEK TVYVDKLIRC KFQDNLEFLQ 101 WLKKHWIRHK DESVYDPDAR RKYRPIITNN SATKPRTVSN PTTAKRSSST 151 GTGSAMSGGL ATRHSSLGIN GSRKTSVTQG QLVAIQAELT KSQETIGSLN 201 EEIEQYKGTV STLEIEREFY FNKLRDIEIL VHTTQDLINE GVYKFNDETI 251 TGHGNGNGGA LLRFVKKVES ILYATAEGFE MNDGEDELND KNLGEHGTVP 301 NQGGYANSNG EVNGNEGSNH DVIMQNDEGE VGVSNNLIID EETF*

Amino Acid Sequence (or in FASTA format)

       1  MSAGIGESRT ELLTWLNGLL NLNYKKIEEC GTGAAYCQIM DSIYGDLPMN
      51  RVKFNATAEY EFQTNYKILQ SCFSRHGIEK TVYVDKLIRC KFQDNLEFLQ
     101  WLKKHWIRHK DESVYDPDAR RKYRPIITNN SATKPRTVSN PTTAKRSSST
     151  GTGSAMSGGL ATRHSSLGIN GSRKTSVTQG QLVAIQAELT KSQETIGSLN
     201  EEIEQYKGTV STLEIEREFY FNKLRDIEIL VHTTQDLINE GVYKFNDETI
     251  TGHGNGNGGA LLRFVKKVES ILYATAEGFE MNDGEDELND KNLGEHGTVP
     301  NQGGYANSNG EVNGNEGSNH DVIMQNDEGE VGVSNNLIID EETF*

external links for Bim1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA
	YeastRC Mass Spec (Seattle)
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Bim1p

1)	Schwartz K, et al. (1997) BIM1 encodes a microtubule-binding protein in yeast. Mol Biol Cell 8(12):2677-91
2)	Miller RK, et al. (2000) Bim1p/Yeb1p mediates the Kar9p-dependent cortical attachment of cytoplasmic microtubules. Mol Biol Cell 11(9):2949-59
3)	Su LK, et al. (1995) APC binds to the novel protein EB1. Cancer Res 55(14):2972-7
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41