PMI40/YER003C Protein Information

Standard Name	Pmi40p 1
Systematic Name	Yer003cp
ORF Classification	Verified
Description	Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation (1) Also known as: PMI
Name Description	PhosphoMannose Isomerase 1

Experimental Data
Molecules/cell	5220 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	429
Molecular Weight (Da)	48,188
Isoelectric Point (pI)	5.86

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Pmi40p (InterPro)
Physical Interactions	There are 9 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000016830A \| P29952 MIPS: YER003C NCBI: 172166 \| 603595 \| 6320839 \| 729984 \| NP_010918.1 \| NM_001178894.1 GenBank/EMBL/DDBJ: DAA07653.1 \| M85238 \| U18778
External Classifications	EC: 5.3.1.8 [Mannose-6-phosphate isomerase]

Amino Acid Sequence (or in FASTA format)
1 MSNKLFRLDA GYQQYDWGKI GSSSAVAQFA AHSDPSVQIE QDKPYAELWM 51 GTHSKMPSYN HESKESLRDI ISKNPSAMLG KDIIDKFHAT NELPFLFKVL 101 SIEKVLSIQA HPDKALGKIL HAQDPKNYPD DNHKPEMAIA VTDFEGFCGF 151 KPLQEIADEL KRIPELRNIV GEETSRNFIE NIQPSAQKGS PEDEQNKKLL 201 QAVFSRVMNA SDDKIKIQAR SLVERSKNSP SDFNKPDLPE LIQRLNKQFP 251 DDVGLFCGCL LLNHCRLNAG EAIFLRAKDP HAYISGDIME CMAASDNVVR 301 AGFTPKFKDV KNLVSMLTYT YDPVEKQKMQ PLKFDRSSGN GKSVLYNPPI 351 EEFAVLETTF DEKLGQRHFE GVDGPSILIT TKGNGYIKAD GQKLKAEPGF 401 VFFIAPHLPV DLEAEDEAFT TYRAFVEPN*

Amino Acid Sequence (or in FASTA format)

       1  MSNKLFRLDA GYQQYDWGKI GSSSAVAQFA AHSDPSVQIE QDKPYAELWM
      51  GTHSKMPSYN HESKESLRDI ISKNPSAMLG KDIIDKFHAT NELPFLFKVL
     101  SIEKVLSIQA HPDKALGKIL HAQDPKNYPD DNHKPEMAIA VTDFEGFCGF
     151  KPLQEIADEL KRIPELRNIV GEETSRNFIE NIQPSAQKGS PEDEQNKKLL
     201  QAVFSRVMNA SDDKIKIQAR SLVERSKNSP SDFNKPDLPE LIQRLNKQFP
     251  DDVGLFCGCL LLNHCRLNAG EAIFLRAKDP HAYISGDIME CMAASDNVVR
     301  AGFTPKFKDV KNLVSMLTYT YDPVEKQKMQ PLKFDRSSGN GKSVLYNPPI
     351  EEFAVLETTF DEKLGQRHFE GVDGPSILIT TKGNGYIKAD GQKLKAEPGF
     401  VFFIAPHLPV DLEAEDEAFT TYRAFVEPN*

external links for Pmi40p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Pmi40p

1)	Smith DJ, et al. (1992) PMI40, an intron-containing gene required for early steps in yeast mannosylation. Mol Cell Biol 12(7):2924-30
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41