HXT13/YEL069C Protein Information

Standard Name	Hxt13p
Systematic Name	Yel069cp
ORF Classification	Verified
Description	Hexose transporter; induced in the presence of non-fermentable carbon sources, induced by low levels of glucose, repressed by high levels of glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication (1, 2, 3)
Name Description	HeXose Transporter

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	564
Molecular Weight (Da)	62,734
Isoelectric Point (pI)	7.19

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Hxt13p (InterPro)
Transmembrane Domains	There are 12 total predicted transmembrane domains (TMHMM)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012CFBE \| P39924 MIPS: YEL069C NCBI: 51830305 \| 603249 \| 6320766 \| 729784 \| NP_010845.1 \| NM_001178884.1 GenBank/EMBL/DDBJ: DAA07586.1 \| AY723801 \| U18795
External Classifications	TC: 2.A.1.1 [The Sugar Porter (SP) Family]

Amino Acid Sequence (or in FASTA format)
1 MSSAQSSIDS DGDVRDADIH VAPPVEKEWS DGFDDNEVIN GDNVEPPKRG 51 LIGYLVIYLL CYPISFGGFL PGWDSGITAG FINMDNFKMN FGSYKHSTGE 101 YYLSNVRMGL LVAMFSIGCA IGGLIFARLA DTLGRRLAIV IVVLVYMVGA 151 IIQISSNHKW YQYFVGKIIY GLGAGGCSVL CPMLLSEIAP TDLRGGLVSL 201 YQLNMTFGIF LGYCSVYGTR KYDNTAQWRV PLGLCFLWAL IIIIGMLLVP 251 ESPRYLIECE RHEEARASIA KINKVSPEDP WVLKQADEIN AGVLAQRELG 301 EASWKELFSV KTKVLQRLIT GILVQTFLQL TGENYFFFYG TTIFKSVGLT 351 DGFETSIVLG TVNFFSTIIA VMVVDKIGRR KCLLFGAAGM MACMVIFASI 401 GVKCLYPHGQ DGPSSKGAGN AMIVFTCFYI FCFATTWAPV AYIVVAESFP 451 SKVKSRAMSI STACNWLWQF LIGFFTPFIT GSIHFYYGYV FVGCLVAMFL 501 YVFFFLPETI GLSLEEIQLL YEEGIKPWKS ASWVPPSRRG ISSEESKTEK 551 KDWKKFLKFS KNSD*

Amino Acid Sequence (or in FASTA format)

       1  MSSAQSSIDS DGDVRDADIH VAPPVEKEWS DGFDDNEVIN GDNVEPPKRG
      51  LIGYLVIYLL CYPISFGGFL PGWDSGITAG FINMDNFKMN FGSYKHSTGE
     101  YYLSNVRMGL LVAMFSIGCA IGGLIFARLA DTLGRRLAIV IVVLVYMVGA
     151  IIQISSNHKW YQYFVGKIIY GLGAGGCSVL CPMLLSEIAP TDLRGGLVSL
     201  YQLNMTFGIF LGYCSVYGTR KYDNTAQWRV PLGLCFLWAL IIIIGMLLVP
     251  ESPRYLIECE RHEEARASIA KINKVSPEDP WVLKQADEIN AGVLAQRELG
     301  EASWKELFSV KTKVLQRLIT GILVQTFLQL TGENYFFFYG TTIFKSVGLT
     351  DGFETSIVLG TVNFFSTIIA VMVVDKIGRR KCLLFGAAGM MACMVIFASI
     401  GVKCLYPHGQ DGPSSKGAGN AMIVFTCFYI FCFATTWAPV AYIVVAESFP
     451  SKVKSRAMSI STACNWLWQF LIGFFTPFIT GSIHFYYGYV FVGCLVAMFL
     501  YVFFFLPETI GLSLEEIQLL YEEGIKPWKS ASWVPPSRRG ISSEESKTEK
     551  KDWKKFLKFS KNSD*

external links for Hxt13p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	TCDB
	DIP	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Hxt13p

1)	Ozcan S and Johnston M (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69
2)	Greatrix BW and van Vuuren HJ (2006) Expression of the HXT13, HXT15 and HXT17 genes in Saccharomyces cerevisiae and stabilization of the HXT1 gene transcript by sugar-induced osmotic stress. Curr Genet 49(4):205-17
3)	Katju V, et al. (2009) Variation in gene duplicates with low synonymous divergence in Saccharomyces cerevisiae relative to Caenorhabditis elegans. Genome Biol 10(7):R75