CIN8/YEL061C Protein Information Help

Standard Name Cin8p
Systematic Name Yel061cp
Alias Ksl2p , Sds15p 1
ORF Classification Verified
Description Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation (2, 3, 4)
Name Description Chromosome INstability 5
Experimental Data
Molecules/cell 238 6
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,000
Molecular Weight (Da) 113,310
Isoelectric Point (pI) 8.17

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Cin8p (InterPro)
Physical Interactions There are 29 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001D4779 | P27895
MIPS: YEL061C
NCBI: 171225 | 3542 | 37362641 | 485971 | 603257 | 85681922 | NP_010853.2
GenBank/EMBL/DDBJ: DAA07593.1 | M90522 | U18795 | X79105 | Z11859
Amino Acid Sequence (or in FASTA format)
 
       1  MPAENQNTGQ DRSSNSISKN GNSQVGCHTV PNEELNITVA VRCRGRNERE
      51  ISMKSSVVVN VPDITGSKEI SINTTGDTGI TAQMNAKRYT VDKVFGPGAS
     101  QDLIFDEVAG PLFQDFIKGY NCTVLVYGMT STGKTYTMTG DEKLYNGELS
     151  DAAGIIPRVL LKLFDTLELQ QNDYVVKCSF IELYNEELKD LLDSNSNGSS
     201  NTGFDGQFMK KLRIFDSSTA NNTTSNSASS SRSNSRNSSP RSLNDLTPKA
     251  ALLRKRLRTK SLPNTIKQQY QQQQAVNSRN NSSSNSGSTT NNASSNTNTN
     301  NGQRSSMAPN DQTNGIYIQN LQEFHITNAM EGLNLLQKGL KHRQVASTKM
     351  NDFSSRSHTI FTITLYKKHQ DELFRISKMN LVDLAGSENI NRSGALNQRA
     401  KEAGSINQSL LTLGRVINAL VDKSGHIPFR ESKLTRLLQD SLGGNTKTAL
     451  IATISPAKVT SEETCSTLEY ASKAKNIKNK PQLGSFIMKD ILVKNITMEL
     501  AKIKSDLLST KSKEGIYMSQ DHYKNLNSDL ESYKNEVQEC KREIESLTSK
     551  NALLVKDKLK SKETIQSQNC QIESLKTTID HLRAQLDKQH KTEIEISDFN
     601  NKLQKLTEVM QMALHDYKKR ELDLNQKFEM HITKEIKKLK STLFLQLNTM
     651  QQESILQETN IQPNLDMIKN EVLTLMRTMQ EKAELMYKDC VKKILNESPK
     701  FFNVVIEKID IIRVDFQKFY KNIAENLSDI SEENNNMKQY LKNHFFKNNH
     751  QELLNRHVDS TYENIEKRTN EFVENFKKVL NDHLDENKKL IMQNLTTATS
     801  AVIDQEMDLF EPKRVKWENS FDLINDCDSM NNEFYNSMAA TLSQIKSTVD
     851  TSSNSMNESI SVMKGQVEES ENAISLLKNN TKFNDQFEQL INKHNMLKDN
     901  IKNSITSTHS HITNVDDIYN TIENIMKNYG NKENATKDEM IENILKEIPN
     951  LSKKMPLRLS NINSNSVQSV ISPKKHAIED ENKSSENVDN EGSRKMLKIE
    1001  *

external links for Cin8p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) BioPIXIE MIPS YeastGFP
Candida (CandidaDB) CYC2008 (complexes) Pfam domains YeastRC Public Image Repository
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Cin8p
1) Sussel L, et al.  (1995) Suppressors of defective silencing in yeast: effects on transcriptional repression at the HMR locus, cell growth and telomere structure. Genetics 141(3):873-88
2) Hoyt MA, et al.  (1992) Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly. J Cell Biol 118(1):109-20
3) Saunders WS and Hoyt MA  (1992) Kinesin-related proteins required for structural integrity of the mitotic spindle. Cell 70(3):451-8
4) Roof DM, et al.  (1992) Kinesin-related proteins required for assembly of the mitotic spindle. J Cell Biol 118(1):95-108
5) Stearns T, et al.  (1990) Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function. Genetics 124(2):251-62
6) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41