YEL045C Protein Information Help

Systematic Name Yel045cp
ORF Classification Dubious
Description Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; deletion gives MMS sensitivity, growth defect under alkaline conditions, less than optimal growth upon citric acid stress (1, 2, 3)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 141
Molecular Weight (Da) 16,468
Isoelectric Point (pI) 10.49

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Post-translational Modifications PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Yel045cp (InterPro)
Transmembrane Domains There are 3 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013AC27 | P32616
MIPS: YEL045C
NCBI: 418417 | 45270776 | 603633
GenBank/EMBL/DDBJ: AY558443 | U18779
Amino Acid Sequence (or in FASTA format)
 
       1  MKCHAKRTLA FLATALPLSG KSRACTRTPQ SFASGFRAAA PFLFSRCFAL
      51  CITHCALFHL PYSFTGFSFY FFVFFRLFLH WIYAFCICNS TYVYIYKQVL
     101  SLPVKSSMCP SRLSCSVWYR VILTYIYVHC FRWLVRNHLL S*

external links for Yel045cp
Homologs Interaction Resources Protein databases/Other Localization Resources
Ashbya (AGD) BOND SCOP Superfamily YPL+
YGOB BioPIXIE GPMdb (Mass Spec.) YeastGFP
YOGY CYC2008 (complexes) MIPS

Complexome Pfam domains

GeneMANIA

References cited on this page View Complete Literature Guide for Yel045cp
1) Lawrence CL, et al.  (2004) Evidence of a new role for the high-osmolarity glycerol mitogen-activated protein kinase pathway in yeast: regulating adaptation to citric acid stress. Mol Cell Biol 24(8):3307-23
2) Chang M, et al.  (2002) A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage. Proc Natl Acad Sci U S A 99(26):16934-9
3) Serrano R, et al.  (2004) Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. J Biol Chem 279(19):19698-704