GDA1/YEL042W Protein Information

Standard Name	Gda1p
Systematic Name	Yel042wp
ORF Classification	Verified
Description	Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate (1)
Name Description	Guanosine DiphosphatAse

Experimental Data
Molecules/cell	8680 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	518
Molecular Weight (Da)	56,821
Isoelectric Point (pI)	5.07

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Gda1p (InterPro)
Transmembrane Domains	There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 9 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012B37F \| P32621 MIPS: YEL042W NCBI: 349393 \| 418404 \| 51830299 \| 603637 \| 6320793 \| NP_010872.1 GenBank/EMBL/DDBJ: DAA07611.1 \| AY723798 \| L19560 \| U18779
External Classifications	EC: 3.6.1.42 [Guanosine-diphosphatase]

Amino Acid Sequence (or in FASTA format)
1 MAPIFRNYRF AIGAFAVIML ILLIKTSSIG PPSIARTVTP NASIPKTPED 51 ISILPVNDEP GYLQDSKTEQ NYPELADAVK SQTSQTCSEE HKYVIMIDAG 101 STGSRVHIYK FDVCTSPPTL LDEKFDMLEP GLSSFDTDSV GAANSLDPLL 151 KVAMNYVPIK ARSCTPVAVK ATAGLRLLGD AKSSKILSAV RDHLEKDYPF 201 PVVEGDGVSI MGGDEEGVFA WITTNYLLGN IGANGPKLPT AAVFDLGGGS 251 TQIVFEPTFP INEKMVDGEH KFDLKFGDEN YTLYQFSHLG YGLKEGRNKV 301 NSVLVENALK DGKILKGDNT KTHQLSSPCL PPKVNATNEK VTLESKETYT 351 IDFIGPDEPS GAQCRFLTDE ILNKDAQCQS PPCSFNGVHQ PSLVRTFKES 401 NDIYIFSYFY DRTRPLGMPL SFTLNELNDL ARIVCKGEET WNSVFSGIAG 451 SLDELESDSH FCLDLSFQVS LLHTGYDIPL QRELRTGKKI ANKEIGWCLG 501 ASLPLLKADN WKCKIQSA*

Amino Acid Sequence (or in FASTA format)

       1  MAPIFRNYRF AIGAFAVIML ILLIKTSSIG PPSIARTVTP NASIPKTPED
      51  ISILPVNDEP GYLQDSKTEQ NYPELADAVK SQTSQTCSEE HKYVIMIDAG
     101  STGSRVHIYK FDVCTSPPTL LDEKFDMLEP GLSSFDTDSV GAANSLDPLL
     151  KVAMNYVPIK ARSCTPVAVK ATAGLRLLGD AKSSKILSAV RDHLEKDYPF
     201  PVVEGDGVSI MGGDEEGVFA WITTNYLLGN IGANGPKLPT AAVFDLGGGS
     251  TQIVFEPTFP INEKMVDGEH KFDLKFGDEN YTLYQFSHLG YGLKEGRNKV
     301  NSVLVENALK DGKILKGDNT KTHQLSSPCL PPKVNATNEK VTLESKETYT
     351  IDFIGPDEPS GAQCRFLTDE ILNKDAQCQS PPCSFNGVHQ PSLVRTFKES
     401  NDIYIFSYFY DRTRPLGMPL SFTLNELNDL ARIVCKGEET WNSVFSGIAG
     451  SLDELESDSH FCLDLSFQVS LLHTGYDIPL QRELRTGKKI ANKEIGWCLG
     501  ASLPLLKADN WKCKIQSA*

external links for Gda1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA
	YeastRC Mass Spec (Seattle)

References cited on this page View Complete Literature Guide for Gda1p

1)	Berninsone P, et al. (1994) The Golgi guanosine diphosphatase is required for transport of GDP-mannose into the lumen of Saccharomyces cerevisiae Golgi vesicles. J Biol Chem 269(1):207-11
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41