UTR2/YEL040W Protein Information Help

Standard Name Utr2p 1
Systematic Name Yel040wp
Alias Crh2p 2
ORF Classification Verified
Description Chitin transglycosylase that functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar to and functionally redundant with Crh1; glycosylphosphatidylinositol (GPI)-anchored protein localized to bud neck (2, 3, 4, 5, 6)
Name Description Unidentified TRanscript 7
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 467
Molecular Weight (Da) 49,906
Isoelectric Point (pI) 4.45

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Utr2p (InterPro)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 7 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000168308 | P32623
MIPS: YEL040W
NCBI: 347502 | 398364247 | 4261675 | 430830 | 51013479 | 586175 | 603639 | 93141247 | NP_010874.3
GenBank/EMBL/DDBJ: DAA07613.1 | AY693014 | L22173 | S65964 | S66130 | U18779
External Classifications EC: 3.2.-.- [Glycosylases]
Amino Acid Sequence (or in FASTA format)
 
       1  MAIVNSWLIC LVSIFSFVVR VEAATFCNAT QACPEDKPCC SQYGECGTGQ
      51  YCLNNCDVRY SFSHDSCMPV PICKSSSTKF KDYSSKLGNA NTFLGNVSEA
     101  DWLYTGDVLD YDDEESLILA MPKNSGGTVL SSTRAVWYGK VSARIKTSHL
     151  AGVVTGFILY SGAGDELDYE FVGADLETAQ TNFYWESVLN YTNSANISTT
     201  DTFENYHTYE LDWHEDYVTW SIDGVVGRTL YKNETYNATT QKYQYPQTPS
     251  KVDISIWPGG NSTNAPGTIA WSGGEINWDA SDISNPGYYY AIVNEVNITC
     301  YDPPSDTKKN GTSAYVYTSS SEFLAKDIAI TDDEVMMDSD EGSGLDPHKG
     351  ATTSSTQKSS SSTATSSSKT SSDHSSSTKK SSKTSSTASS SSSSSSSSSS
     401  SSSTATKNGD KVVSSVSSSV TSQTQTTSSV SGSASSSTSS MSGNNAGANV
     451  AANWRLTVLC VILGYVL*

external links for Utr2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB GeneMANIA

YOGY


References cited on this page View Complete Literature Guide for Utr2p
1) Melnick L and Sherman F  (1993) The gene clusters ARC and COR on chromosomes 5 and 10, respectively, of Saccharomyces cerevisiae share a common ancestry. J Mol Biol 233(3):372-88
2) Rodriguez-Pena JM, et al.  (2000) A novel family of cell wall-related proteins regulated differently during the yeast life cycle. Mol Cell Biol 20(9):3245-55
3) Rodriguez-Pena JM, et al.  (2002) Mechanisms for targeting of the Saccharomyces cerevisiae GPI-anchored cell wall protein Crh2p to polarised growth sites. J Cell Sci 115(Pt 12):2549-58
4) Cabib E, et al.  (2007) Crh1p and Crh2p are required for the cross-linking of chitin to beta(1-6)glucan in the Saccharomyces cerevisiae cell wall. Mol Microbiol 63(3):921-35
5) Cabib E, et al.  (2008) Assembly of the Yeast Cell Wall: Crh1p AND Crh2p ACT AS TRANSGLYCOSYLASES IN VIVO AND IN VITRO. J Biol Chem 283(44):29859-72
6) Cabib E  (2009) Two novel techniques for determination of polysaccharide cross-links show that Crh1p and Crh2p attach chitin to both beta(1-6)- and beta(1-3)glucan in the Saccharomyces cerevisiae cell wall. Eukaryot Cell 8(11):1626-36
7) Barry K, et al.  (1987) Physical analysis of the COR region: a cluster of six genes in Saccharomyces cerevisiae. Mol Cell Biol 7(2):632-8