GCN4/YEL009C Protein Information 
| Standard Name | Gcn4p |
|---|---|
| Systematic Name | Yel009cp |
| Alias | Aas3p 1 , Arg9p 1 , Aas101p 2 |
| ORF Classification | Verified |
| Description | Basic leucine zipper (bZIP) transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels (3, 4) |
| Name Description | General Control Nonderepressible 5 |
| Click on image for expanded interactive view |
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external links for Gcn4p
| Homologs | Interaction Resources | Protein databases/Other | Localization Resources |
|---|---|---|---|
| BLASTP (NCBI) | BioGRID | SCOP Superfamily | Organelle DB |
| Ashbya (AGD) | BOND | GPMdb (Mass Spec.) | YPL+ |
| YGOB | BioPIXIE | MIPS | YeastGFP |
| YOGY | CYC2008 (complexes) | Pfam domains | YeastRC Public Image Repository |
| Complexome | YeastRC Structure Prediction (Seattle) | ||
| DIP | |||
| GeneMANIA | |||
| YeastRC Two-Hybrid (Seattle) |
References cited on this page View Complete Literature Guide for Gcn4p
| 1) | Hinnebusch AG and Fink GR (1983) Positive regulation in the general amino acid control of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 80(17):5374-8 |
| 2) | Thireos G, et al. (1984) 5' untranslated sequences are required for the translational control of a yeast regulatory gene. Proc Natl Acad Sci U S A 81(16):5096-100 |
| 3) | Hinnebusch A (1992) "General and Pathway-specific Regulatory Mechanisms Controlling the Synthesis of Amino Acid Biosynthetic Enzymes in Saccharomyces cerevisiae". Pp. 319-414 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by Jones EW, Pringle JR and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press |
| 4) | Hinnebusch AG and Natarajan K (2002) Gcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress. Eukaryot Cell 1(1):22-32 |
| 5) | Lucchini G, et al. (1984) Positive regulatory interactions of the HIS4 gene of Saccharomyces cerevisiae. Mol Cell Biol 4(7):1326-33 |
