OCA4/YCR095C Protein Information

Standard Name	Oca4p 1, 2
Systematic Name	Ycr095cp
ORF Classification	Uncharacterized
Description	Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts (3, 4)
Name Description	Oxidant-induced Cell-cycle Arrest 1

Experimental Data
Molecules/cell	5370 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	362
Molecular Weight (Da)	41,647
Isoelectric Point (pI)	8.78

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Oca4p (InterPro)
Physical Interactions	There are 15 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013A7A2 \| P25366 MIPS: YCR095C NCBI: 140556 \| 1907233 \| 6319938 \| NP_010019.1 GenBank/EMBL/DDBJ: DAA07564.1 \| X59720

Amino Acid Sequence (or in FASTA format)
1 MLVPPANFGI AEEGIYRCSK VETLNLSFLE TLNLKTAIFI GGQEPSKFFK 51 DFFTRSSIKW IVLRMSDFSA AAVPVKSSSV SNANLYSNNN STLSLQEEKK 101 KSTANGSQNS TTGDPVIQEE LAYHLTDNDD LMLIKSTCLK RTFKTLLNVD 151 NYNVLLVDKT ALVIGILRKI QKWNIASIIN EYRLFSGKNR NYFAETFLEI 201 INIEIEQEKD NKTIVDNKAK KLPLENNRTH SIEYKANSGK LIRVNEDDLC 251 REPEVPQRLL TLINQIETKV KNNKVLQVSG VLGDDLKKTS SDLGIFGHRY 301 RLAFNKKENG DYGYYKARGK DNVKIRIPCD SELPDWFRFQ RDLWEKENVP 351 EEHHFYREHI FT*

Amino Acid Sequence (or in FASTA format)

       1  MLVPPANFGI AEEGIYRCSK VETLNLSFLE TLNLKTAIFI GGQEPSKFFK
      51  DFFTRSSIKW IVLRMSDFSA AAVPVKSSSV SNANLYSNNN STLSLQEEKK
     101  KSTANGSQNS TTGDPVIQEE LAYHLTDNDD LMLIKSTCLK RTFKTLLNVD
     151  NYNVLLVDKT ALVIGILRKI QKWNIASIIN EYRLFSGKNR NYFAETFLEI
     201  INIEIEQEKD NKTIVDNKAK KLPLENNRTH SIEYKANSGK LIRVNEDDLC
     251  REPEVPQRLL TLINQIETKV KNNKVLQVSG VLGDDLKKTS SDLGIFGHRY
     301  RLAFNKKENG DYGYYKARGK DNVKIRIPCD SELPDWFRFQ RDLWEKENVP
     351  EEHHFYREHI FT*

external links for Oca4p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Oca4p

1)	Warringer, J, et al. (2006) personal communication
2)	Addinall SG, et al. (2008) A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae. Genetics 180(4):2251-66
3)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4)	Kushner DB, et al. (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41