KIN82/YCR091W Protein Information Help

Standard Name Kin82p
Systematic Name Ycr091wp
Alias Fpk2p 1
ORF Classification Verified
Description Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases) Lem3p-Dnf1p/Dnf2p; KIN82 has a paralog, FPK1, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description protein KINase
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 720
Molecular Weight (Da) 81,462
Isoelectric Point (pI) 8.72

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Kin82p (InterPro)
Physical Interactions There are 37 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000158E847 | P25341
MIPS: YCR091W
NCBI: 14588960 | 330443488 | 341941029 | 45644960 | NP_010015.3
GenBank/EMBL/DDBJ: DAA07560.2 | X59720
External Classifications EC: 2.7.11.1 [Non-specific serine/threonine protein kinase]
Amino Acid Sequence (or in FASTA format)
 
       1  MTQQEYRSPS QRLSKGRSMS LPKIFARNLR SLQNNAPPGK NINVNCLNVN
      51  SCSLSASPSS QINMACNGNK QDLPIPFPLH VECNDSWSSS KLNKFKSMFN
     101  HNRSKSSGTT DASTSEKGTH KREPRSTIHT ELLQSSIIGE PNVHSTTSST
     151  LIPNEAICST PNEISGSSSP DAELFTFDMP TDPSSFHTPS SPSYIAKDSR
     201  NLSNGSLNDI NENEELQNFH RKISENGSAS PLANLSLSNS PIDSPRKNSE
     251  TRKDQIPMNI TPRLRRAASE PFNTAKDGLM REDYIALKQP PSLGDIVEPR
     301  RSRRLRTKSF GNKFQDITVE PQSFEKIRLL GQGDVGKVYL VRERDTNQIF
     351  ALKVLNKHEM IKRKKIKRVL TEQEILATSD HPFIVTLYHS FQTKDYLYLC
     401  MEYCMGGEFF RALQTRKSKC IAEEDAKFYA SEVVAALEYL HLLGFIYRDL
     451  KPENILLHQS GHVMLSDFDL SIQATGSKKP TMKDSTYLDT KICSDGFRTN
     501  SFVGTEEYLA PEVIRGNGHT AAVDWWTLGI LIYEMLFGCT PFKGDNSNET
     551  FSNILTKDVK FPHDKEVSKN CKDLIKKLLN KNEAKRLGSK SGAADIKRHP
     601  FFKKVQWSFL RNQDPPLIPA LNDNGCELPF ILSCNKHPKR NSVSEQETKM
     651  FCEKVANDDE IDEADPFHDF NSMSLTKKDH NILTYSENYT YGKILYKATC
     701  TRPRHNSSHR SFFKDIIPEL *

external links for Kin82p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
YGOB BioPIXIE MIPS YeastGFP
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Kin82p
1) Nakano K, et al.  (2008) Protein kinases Fpk1p and Fpk2p are novel regulators of phospholipid asymmetry. Mol Biol Cell 19(4):1783-97
2) Wilson C, et al.  (1992) A putative serine/threonine protein kinase gene on chromosome III of Saccharomyces cerevisiae. Yeast 8(1):71-7
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Roelants FM, et al.  (2010) A protein kinase network regulates the function of aminophospholipid flippases. Proc Natl Acad Sci U S A 107(1):34-9