BUD31/YCR063W Protein Information Help

Standard Name Bud31p 1
Systematic Name Ycr063wp
Alias Cwc14p 2
ORF Classification Verified
Description Component of the SF3b subcomplex of the U2 snRNP; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern; facilitates passage through G1/S Start, but is not required for G2/M transition or exit from mitosis (1, 3, 4, 5)
Name Description BUD site selection 1
Experimental Data
Molecules/cell 1900 6
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 157
Molecular Weight (Da) 18,447
Isoelectric Point (pI) 10.19

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Bud31p (InterPro)
Physical Interactions There are 46 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00000531F8 | P25337
MIPS: YCR063W
NCBI: 120626 | 1907203 | 6319908 | NP_009990.1
GenBank/EMBL/DDBJ: DAA07536.1 | X59720
Amino Acid Sequence (or in FASTA format)
 
       1  MPRIKTRRSK PAPDGFEKIK PTLTDFEIQL RDAQKDKSSK LAAKSNEQLW
      51  EIMQLHHQRS RYIYTLYYKR KAISKDLYDW LIKEKYADKL LIAKWRKTGY
     101  EKLCCLRCIQ KNETNNGSTC ICRVPRAQLE EEARKKGTQV SFHQCVHCGC
     151  RGCASTD*

external links for Bud31p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) BioPIXIE MIPS YeastGFP
Candida (CGD) CYC2008 (complexes) Pfam domains YeastRC Public Image Repository
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA


YeastRC Mass Spec (Seattle)


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Bud31p
1) Ni L and Snyder M  (2001) A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Mol Biol Cell 12(7):2147-70
2) Ohi MD, et al.  (2002) Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol Cell Biol 22(7):2011-24
3) Troyanskaya OG, et al.  (2003) A Bayesian framework for combining heterogeneous data sources for gene function prediction (in Saccharomyces cerevisiae). Proc Natl Acad Sci U S A 100(14):8348-53
4) Wang Q, et al.  (2005) Interactions of the yeast SF3b splicing factor. Mol Cell Biol 25(24):10745-54
5) Saha D, et al.  (2012) Context dependent splicing functions of Bud31/Ycr063w define its role in budding and cell cycle progression. Biochem Biophys Res Commun 424(3):579-85
6) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41