CTR86/YCR054C Protein Information

Standard Name	Ctr86p 1
Systematic Name	Ycr054cp
ORF Classification	Verified
Description	Essential protein of unknown function; with orthologs in Ashbya gossypii and Candida albicans; similar to human ATXN10, mutations in which cause spinocerebellar ataxia type 10; codon usage corresponds to that observed for yeast genes expressed at low levels; relative distribution to the nucleus increases upon DNA replication stress (1, 2, 3, 4)
Name Description	Copper TRansport protein

Experimental Data
Molecules/cell	8970 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	563
Molecular Weight (Da)	65,205
Isoelectric Point (pI)	4.67

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ctr86p (InterPro)
Physical Interactions	There are 1 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013A721 \| P25355 MIPS: YCR054C NCBI: 140514 \| 1907197 \| 6319902 \| NP_009983.1 GenBank/EMBL/DDBJ: DAA07531.1 \| X59720

Amino Acid Sequence (or in FASTA format)
1 MPMNNFLDEF NLFDSIITMM KNDPCCVEDY EPIVENLNRI FQRTFNDEEH 51 RKSMANSQLF WERLRDTLEA MLLPASLNEN SSIPYTRTVR GLILMMRNLA 101 AENQEIPQKL LLQNLVIRGF LHATSEYVVD TPLIKHLYIA CLTCLFNIQQ 151 NYSTVDMTTF PALLQFLQYP YGIKLEDGEE EEHFWLPYLF LFKTYLNNDE 201 FSNEFFRDND TPQKDYYCVR DRIFFDIVTA KFIQDQENSF LIEKGRNYLD 251 DSKLEITSID LSVLECISKS LTTASFGKYL NGLEERQPGK FTTLLQILQL 301 VVTSKEDWNT YELTAIMSWC YPILQRLACK DIPAFFNKSC NDYAPSVAIQ 351 LHSTLLSCLD IISDLCKFNH VRKFLISYDS VKILVSLLDT FQKNLLRINF 401 LKGNGDTVNE IKITDHEGNK IEDRLLIFNR VNTNESFIRA DNFPHCKLVI 451 IEILASLVYA HPEIQDQIRE LGGLALILSN CVIDDNDPFI KERSIVCLKF 501 LLKNNAKNQE YVKKMEAQDV VQDDALSKAG FEISVEKGGK VRLVSKEEDP 551 GNENSEIISI DED*

Amino Acid Sequence (or in FASTA format)

       1  MPMNNFLDEF NLFDSIITMM KNDPCCVEDY EPIVENLNRI FQRTFNDEEH
      51  RKSMANSQLF WERLRDTLEA MLLPASLNEN SSIPYTRTVR GLILMMRNLA
     101  AENQEIPQKL LLQNLVIRGF LHATSEYVVD TPLIKHLYIA CLTCLFNIQQ
     151  NYSTVDMTTF PALLQFLQYP YGIKLEDGEE EEHFWLPYLF LFKTYLNNDE
     201  FSNEFFRDND TPQKDYYCVR DRIFFDIVTA KFIQDQENSF LIEKGRNYLD
     251  DSKLEITSID LSVLECISKS LTTASFGKYL NGLEERQPGK FTTLLQILQL
     301  VVTSKEDWNT YELTAIMSWC YPILQRLACK DIPAFFNKSC NDYAPSVAIQ
     351  LHSTLLSCLD IISDLCKFNH VRKFLISYDS VKILVSLLDT FQKNLLRINF
     401  LKGNGDTVNE IKITDHEGNK IEDRLLIFNR VNTNESFIRA DNFPHCKLVI
     451  IEILASLVYA HPEIQDQIRE LGGLALILSN CVIDDNDPFI KERSIVCLKF
     501  LLKNNAKNQE YVKKMEAQDV VQDDALSKAG FEISVEKGGK VRLVSKEEDP
     551  GNENSEIISI DED*

external links for Ctr86p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Ctr86p

1)	Mannhaupt G, et al. (1990) Analysis of the THR4 region on chromosome III of the yeast Saccharomyces cerevisiae. Yeast 6(4):353-61
2)	Rieger KJ, et al. (1997) Large-scale phenotypic analysis--the pilot project on yeast chromosome III. Yeast 13(16):1547-62
3)	Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
4)	Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41