MATALPHA2/YCR039C Protein Information Help

Standard Name Matalpha2p 1
Systematic Name Ycr039cp
Alias Alpha2p
ORF Classification Verified
Description Homeobox-domain protein; with Mcm1p, represses a-specific genes in haploids; acts with A1p to repress transcription of haploid-specific genes in diploids; one of two genes encoded by the MATalpha mating type cassette (2, 3)
Name Description MATing type protein ALPHA
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 210
Molecular Weight (Da) 24,282
Isoelectric Point (pI) 10.24

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Matalpha2p (InterPro)
Physical Interactions There are 20 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000012EBF8 | P0CY08
MIPS: YCR039C
NCBI: 1000052 | 171903 | 1907181 | 21466067 | 27573686 | 2981795 | 338818297 | 499332 | 51013071 | 6319785 | 63536787 | NP_009866.1 | NP_009868.3 | NM_001178708.1 | NM_001178753.1
GenBank/EMBL/DDBJ: AAA34762.1 | AAT92829.1 | CAA42306.1 | CAA45335.1 | DAA07518.1 | AY692810 | L00060 | X59720 | X63853
Amino Acid Sequence (or in FASTA format)
       1  MNKIPIKDLL NPQITDEFKS SILDINKKLF SICCNLPKLP ESVTTEEEVE
      51  LRDILGFLSR ANKNRKISDE EKKLLQTTSQ LTTTITVLLK EMRSIENDRS
     101  NYQLTQKNKS ADGLVFNVVT QDMINKSTKP YRGHRFTKEN VRILESWFAK
     151  NIENPYLDTK GLENLMKNTS LSRIQIKNWV SNRRRKEKTI TIAPELADLL
     201  SGEPLAKKKE *                                          

external links for Matalpha2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) Organelle DB
YGOB CYC2008 (complexes) MIPS YPL+
YOGY Complexome Pfam domains YeastGFP

GeneMANIA YeastRC Structure Prediction (Seattle)

IMP

1) Nasmyth KA, et al.  (1981) A position effect in the control of transcription at yeast mating type loci. Nature 289(5795):244-50
2) Porter SD and Smith M  (1986) Homoeo-domain homology in yeast MAT alpha 2 is essential for repressor activity. Nature 320(6064):766-8
3) Siliciano PG and Tatchell K  (1986) Identification of the DNA sequences controlling the expression of the MAT alpha locus of yeast. Proc Natl Acad Sci U S A 83(8):2320-4