MATALPHA2/YCR039C Protein Information

Standard Name	Matalpha2p 1
Systematic Name	Ycr039cp
Alias	Alpha2p
ORF Classification	Verified
Description	Homeobox-domain protein that, with Mcm1p, represses a-specific genes in haploids; acts with A1p to repress transcription of haploid-specific genes in diploids; one of two genes encoded by the MATalpha mating type cassette (2, 3)
Name Description	MATing type protein ALPHA

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	210
Molecular Weight (Da)	24,282
Isoelectric Point (pI)	10.24

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Matalpha2p (InterPro)
Physical Interactions	There are 20 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012EBF8 \| P0CY08 MIPS: YCR039C NCBI: 1000052 \| 1000053 \| 1310758 \| 171903 \| 1907181 \| 21466067 \| 27573686 \| 27573687 \| 27573688 \| 27573689 \| 2981795 \| 2981796 \| 3212446 \| 338818297 \| 499332 \| 51013071 \| 6319785 \| 63536787 \| NP_009866.1 \| NP_009868.3 GenBank/EMBL/DDBJ: DAA07518.1 \| AY692810 \| L00060 \| X59720 \| X63853

Amino Acid Sequence (or in FASTA format)
1 MNKIPIKDLL NPQITDEFKS SILDINKKLF SICCNLPKLP ESVTTEEEVE 51 LRDILGFLSR ANKNRKISDE EKKLLQTTSQ LTTTITVLLK EMRSIENDRS 101 NYQLTQKNKS ADGLVFNVVT QDMINKSTKP YRGHRFTKEN VRILESWFAK 151 NIENPYLDTK GLENLMKNTS LSRIQIKNWV SNRRRKEKTI TIAPELADLL 201 SGEPLAKKKE *

Amino Acid Sequence (or in FASTA format)

       1  MNKIPIKDLL NPQITDEFKS SILDINKKLF SICCNLPKLP ESVTTEEEVE
      51  LRDILGFLSR ANKNRKISDE EKKLLQTTSQ LTTTITVLLK EMRSIENDRS
     101  NYQLTQKNKS ADGLVFNVVT QDMINKSTKP YRGHRFTKEN VRILESWFAK
     151  NIENPYLDTK GLENLMKNTS LSRIQIKNWV SNRRRKEKTI TIAPELADLL
     201  SGEPLAKKKE *

external links for Matalpha2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Matalpha2p

1)	Nasmyth KA, et al. (1981) A position effect in the control of transcription at yeast mating type loci. Nature 289(5795):244-50
2)	Porter SD and Smith M (1986) Homoeo-domain homology in yeast MAT alpha 2 is essential for repressor activity. Nature 320(6064):766-8
3)	Siliciano PG and Tatchell K (1986) Identification of the DNA sequences controlling the expression of the MAT alpha locus of yeast. Proc Natl Acad Sci U S A 83(8):2320-4