SNT1/YCR033W Protein Information Help

Standard Name Snt1p 1
Systematic Name Ycr033wp
ORF Classification Verified
Description Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein; mutant has increased aneuploidy tolerance (1, 2, 3)
Name Description SaNT domains 1
Experimental Data
Molecules/cell 396 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,226
Molecular Weight (Da) 138,396
Isoelectric Point (pI) 9.95

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Snt1p (InterPro)
Physical Interactions There are 47 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000052F4A | P25357
MIPS: YCR033W
NCBI: 10383795 | 14588944 | 244239 | 32363488 | 4807 | NP_009962.2
GenBank/EMBL/DDBJ: DAA07512.1 | S78624 | X59075 | X59720
Amino Acid Sequence (or in FASTA format)
 
       1  MGYPPPTRRL GDKKRYHYSN NPNRRHPSAV YSKNSFPKSS NNGFVSSPTA
      51  DNSTNPSVTP STASVPLPTA APGSTFGIEA PRPSRYDPSS VSRPSSSSYS
     101  STRKIGSRYN PDVERSSSTT SSTPESMNTS TITHTNTDIG NSRYSRKTMS
     151  RYNPQSTSST NVTHFPSALS NAPPFYVANG SSRRPRSMDD YSPDVTNKLE
     201  TNNVSSVNNN SPHSYYSRSN KWRSIGTPSR PPFDNHVGNM TTTSNTNSIH
     251  QREPFWKANS TTILKSTHSQ SSPSLHTKKF HDANKLDKPE ASVKVETPSK
     301  DETKAISYHD NNFPPRKSVS KPNAPLEPDN IKVGEEDALG KKEVHKSGRE
     351  IAKEHPTPVK MKEHDELEAR AKKVSKINID GKQDEIWTTA KTVASAVEVS
     401  KESQKELTRS VERKESPEIR DYERAYDPKA LKTDVTKLTV DNDNKSYEEP
     451  LEKVEGCIFP LPKAETRLWE LKNQKRNKII SEQKYLLKKA IRNFSEYPFY
     501  AQNKLIHQQA TGLILTKIIS KIKKEEHLKK INLKHDYFDL QKKYEKECEI
     551  LTKLSENLRK EEIENKRKEH ELMEQKRREE GIETEKEKSL RHPSSSSSSR
     601  RRNRADFVDD AEMENVLLQI DPNYKHYQAA ATIPPLILDP IRKHSYKFCD
     651  VNNLVTDKKL WASRILKDAS DNFTDHEHSL FLEGYLIHPK KFGKISHYMG
     701  GLRSPEECVL HYYRTKKTVN YKQLLIDKNK KRKMSAAAKR RKRKERSNDE
     751  EVEVDESKEE STNTIEKEEK SENNAEENVQ PVLVQGSEVK GDPLGTPEKV
     801  ENMIEQRGEE FAGELENAER VNDLKRAHDE VGEESNKSSV IETNNGVQIM
     851  DPKGAVQNGY YPEETKELDF SLENALQRKK HKSAPEHKTS YWSVRESQLF
     901  PELLKEFGSQ WSLISEKLGT KSTTMVRNYY QRNAARNGWK LLVDETDLKR
     951  DGTSSESVQQ SQILIQPERP NINAYSNIPP QQRPALGYFV GQPTHGHNTS
    1001  ISSIDGSIRP FGPDFHRDTF SKISAPLTTL PPPRLPSIQF PRSEMAEPTV
    1051  TDLRNRPLDH IDTLADAASS VTNNQNFSNE RNAIDIGRKS TTISNLLNNS
    1101  DRSMKSSFQS ASRHEAQLED TPSMNNIVVQ EIKPNITTPR SSSISALLNP
    1151  VNGNGQSNPD GRPLLPFQHA ISQGTPTFPL PAPRTSPISR APPKFNFSND
    1201  PLAALAAVAS APDAMSSFLS KKENNN*

external links for Snt1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
YGOB BioPIXIE MIPS YeastGFP
YOGY CYC2008 (complexes) Pfam domains YeastRC Public Image Repository

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Snt1p
1) Pijnappel WW, et al.  (2001) The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Genes Dev 15(22):2991-3004
2) Cerna D and Wilson DK  (2005) The structure of Sif2p, a WD repeat protein functioning in the SET3 corepressor complex. J Mol Biol 351(4):923-35
3) Torres EM, et al.  (2010) Identification of aneuploidy-tolerating mutations. Cell 143(1):71-83
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41