SAT4/YCR008W Protein Information

Standard Name	Sat4p
Systematic Name	Ycr008wp
Alias	Hal4p 1
ORF Classification	Verified
Description	Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; partially redundant with Hal5p; has similarity to Npr1p (1, 2)

Experimental Data
Molecules/cell	1030 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	603
Molecular Weight (Da)	66,665
Isoelectric Point (pI)	9.89

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Sat4p (InterPro)
Physical Interactions	There are 58 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000135580 \| P25333 MIPS: YCR008W NCBI: 125291 \| 1907151 \| 242395 \| 6319853 \| 951308 \| NP_009934.1 GenBank/EMBL/DDBJ: DAA07486.1 \| S76380 \| X59720 \| Z11114
External Classifications	EC: 2.7.11.1 [Non-specific serine/threonine protein kinase]

Amino Acid Sequence (or in FASTA format)
1 MTGMNDNNAA IPQQTPRKHA LSSKVMQLFR SGSRSSRQGK ASSNIQPPSN 51 INTNVPSASK SAKFGLHTPT TATPRVVSNP SNTAGVSKPG MYMPEYYQSA 101 SPSHSSSSAS LNNHIDINTS KSSSAASLTS SVSALSLSPT SAINISSKSL 151 SPKFSHHSNS NTAITPAPTP TASNINNVNK ITNTSAPICG RFLVHKDGTH 201 EHHLKNAKRQ EKLSTMIKNM VGASKLRGEA KSAVPDIIMD PKTTLKSNKN 251 PPTLFAGFMK QVVDMDDKYP EGAPTSGALN CPERDIYRSD QKDSKNNTHN 301 ITTTKKDRQC FAEKYGRCQE VLGKGAFGVV RICQKKNVSS QDGNKSEKLY 351 AVKEFKRRTS ESAEKYSKRL TSEFCISSSL HHTNIVTTLD LFQDAKGEYC 401 EVMEYCAGGD LFTLVVAAGK LEYMEADCFF KQLIRGVVYM HEMGVCHRDL 451 KPENLLLTHD GVLKITDFGN SECFKMAWEK NIHLSGGVCG SSPYIAPEEY 501 IKEEFDPRPV DIWACGVIYM AMRTGRQLWS SAEKDDPFYM NYLKGRKEKG 551 GYEPIESLKR ARCRNVIYSM LDPVPYRRIN GKQILNSEWG REIKCCHNGR 601 ALK*

Amino Acid Sequence (or in FASTA format)

       1  MTGMNDNNAA IPQQTPRKHA LSSKVMQLFR SGSRSSRQGK ASSNIQPPSN
      51  INTNVPSASK SAKFGLHTPT TATPRVVSNP SNTAGVSKPG MYMPEYYQSA
     101  SPSHSSSSAS LNNHIDINTS KSSSAASLTS SVSALSLSPT SAINISSKSL
     151  SPKFSHHSNS NTAITPAPTP TASNINNVNK ITNTSAPICG RFLVHKDGTH
     201  EHHLKNAKRQ EKLSTMIKNM VGASKLRGEA KSAVPDIIMD PKTTLKSNKN
     251  PPTLFAGFMK QVVDMDDKYP EGAPTSGALN CPERDIYRSD QKDSKNNTHN
     301  ITTTKKDRQC FAEKYGRCQE VLGKGAFGVV RICQKKNVSS QDGNKSEKLY
     351  AVKEFKRRTS ESAEKYSKRL TSEFCISSSL HHTNIVTTLD LFQDAKGEYC
     401  EVMEYCAGGD LFTLVVAAGK LEYMEADCFF KQLIRGVVYM HEMGVCHRDL
     451  KPENLLLTHD GVLKITDFGN SECFKMAWEK NIHLSGGVCG SSPYIAPEEY
     501  IKEEFDPRPV DIWACGVIYM AMRTGRQLWS SAEKDDPFYM NYLKGRKEKG
     551  GYEPIESLKR ARCRNVIYSM LDPVPYRRIN GKQILNSEWG REIKCCHNGR
     601  ALK*

external links for Sat4p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Sat4p

1)	Mulet JM, et al. (1999) A novel mechanism of ion homeostasis and salt tolerance in yeast: the Hal4 and Hal5 protein kinases modulate the Trk1-Trk2 potassium transporter. Mol Cell Biol 19(5):3328-37
2)	Skala J, et al. (1991) The open reading frame YCR101 located on chromosome III from Saccharomyces cerevisiae is a putative protein kinase. Yeast 7(6):651-5
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41