SAT4/YCR008W Protein Information Help

Standard Name Sat4p
Systematic Name Ycr008wp
Alias Hal4p 1
ORF Classification Verified
Description Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; partially redundant with Hal5p; has similarity to Npr1p (1, 2)
Experimental Data
Molecules/cell 1030 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 603
Molecular Weight (Da) 66,665
Isoelectric Point (pI) 9.89

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Sat4p (InterPro)
Physical Interactions There are 58 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000135580 | P25333
MIPS: YCR008W
NCBI: 125291 | 1907151 | 242395 | 6319853 | 951308 | NP_009934.1 | NM_001178721.1
GenBank/EMBL/DDBJ: AAB20894.1 | CAA42325.1 | CAA77445.1 | DAA07486.1 | S76380 | X59720 | Z11114
External Classifications EC: 2.7.11.1 [Non-specific serine/threonine protein kinase]
Amino Acid Sequence (or in FASTA format)
       1  MTGMNDNNAA IPQQTPRKHA LSSKVMQLFR SGSRSSRQGK ASSNIQPPSN
      51  INTNVPSASK SAKFGLHTPT TATPRVVSNP SNTAGVSKPG MYMPEYYQSA
     101  SPSHSSSSAS LNNHIDINTS KSSSAASLTS SVSALSLSPT SAINISSKSL
     151  SPKFSHHSNS NTAITPAPTP TASNINNVNK ITNTSAPICG RFLVHKDGTH
     201  EHHLKNAKRQ EKLSTMIKNM VGASKLRGEA KSAVPDIIMD PKTTLKSNKN
     251  PPTLFAGFMK QVVDMDDKYP EGAPTSGALN CPERDIYRSD QKDSKNNTHN
     301  ITTTKKDRQC FAEKYGRCQE VLGKGAFGVV RICQKKNVSS QDGNKSEKLY
     351  AVKEFKRRTS ESAEKYSKRL TSEFCISSSL HHTNIVTTLD LFQDAKGEYC
     401  EVMEYCAGGD LFTLVVAAGK LEYMEADCFF KQLIRGVVYM HEMGVCHRDL
     451  KPENLLLTHD GVLKITDFGN SECFKMAWEK NIHLSGGVCG SSPYIAPEEY
     501  IKEEFDPRPV DIWACGVIYM AMRTGRQLWS SAEKDDPFYM NYLKGRKEKG
     551  GYEPIESLKR ARCRNVIYSM LDPVPYRRIN GKQILNSEWG REIKCCHNGR
     601  ALK*                                                  

external links for Sat4p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) CYC2008 (complexes) MIPS YeastGFP
YGOB Complexome Pfam domains
YOGY DIP YeastRC Structure Prediction (Seattle)

GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Sat4p
1) Mulet JM, et al.  (1999) A novel mechanism of ion homeostasis and salt tolerance in yeast: the Hal4 and Hal5 protein kinases modulate the Trk1-Trk2 potassium transporter. Mol Cell Biol 19(5):3328-37
2) Skala J, et al.  (1991) The open reading frame YCR101 located on chromosome III from Saccharomyces cerevisiae is a putative protein kinase. Yeast 7(6):651-5
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41