VBA3/YCL069W Protein Information Help

Standard Name Vba3p 1
Systematic Name Ycl069wp
ORF Classification Verified
Description Permease of basic amino acids in the vacuolar membrane; VBA3 has a paralog, VBA5, that arose from a segmental duplication (1, 2)
Name Description Vacuolar Basic Amino acid transporter 1
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 458
Molecular Weight (Da) 50,225
Isoelectric Point (pI) 9.83

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Vba3p (InterPro)
Transmembrane Domains There are 11 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 2 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013A68B | P25594
MIPS: YCL069W
NCBI: 140412 | 5290 | 6319783 | NP_009864.1 | NM_001178710.1
GenBank/EMBL/DDBJ: DAA07419.1 | X59720
External Classifications TC: 2.A.1.3 [The Drug:H+ Antiporter-2 (14 Spanner) (DHA2) Family]
Amino Acid Sequence (or in FASTA format)
 
       1  MNMLIVGRVV ASVGGSGLQT LCFVIGCTMV GERSRPLVIS ILSCAFAVAA
      51  IVGPIIGGAF TTHVTWRWCF YINLPIGGLA IIMFLLTYKA ENKGILQQIK
     101  DAIGTISSFT FSKFRHQVNF KRLMNGIIFK FDFFGFALCS AGLVLFLLGL
     151  TFGGNKYSWN SGQVIAYLVL GVLLFIFSLV YDFFLFDKFN PEPDNISYRP
     201  LLLRRLVAKP AIIIINMVTF LLCTGYNGQM IYSVQFFQLI FASSAWKAGL
     251  HLIPIVITNV IAAIASGVIT KKLGLVKPLL IFGGVLGVIG AGLMTLMTNT
     301  STKSTQIGVL LLPGFSLGFA LQASLMSAQL QITKDRPEAA MDFIEVTAFN
     351  TFMKSLGTTL GGVLSTTVFS ASFHNKVSRA HLEPYEGKTV DDMILYRLQN
     401  YDGSHSTIGN ILSDSIKNVF WMDLGFYALG FLFCSFSSNK KLIIPKKDET
     451  PEDNLEDK*

external links for Vba3p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS
YOGY CYC2008 (complexes) Pfam domains

Complexome TCDB

DIP YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Vba3p
1) Shimazu M, et al.  (2005) A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae. J Biol Chem 280(6):4851-7
2) Katju V, et al.  (2009) Variation in gene duplicates with low synonymous divergence in Saccharomyces cerevisiae relative to Caenorhabditis elegans. Genome Biol 10(7):R75