FYV5/YCL058C Protein Information Help

Standard Name Fyv5p
Systematic Name Ycl058cp
Alias Mdf1p 1
ORF Classification Verified
Description Protein involved in regulation of the mating pathway; binds with Matalpha2p to promoters of haploid-specific genes; required for survival upon exposure to K1 killer toxin; involved in ion homeostasis (1, 2, 3)
Name Description Function required for Yeast Viability 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 152
Molecular Weight (Da) 17,139
Isoelectric Point (pI) 7.25

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Post-translational Modifications PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Fyv5p (InterPro)
Transmembrane Domains There are 2 total predicted transmembrane domains (TMHMM)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013A65E | P25585
MIPS: YCL058C
NCBI: 140399 | 45270178 | 5302 | 6319792 | NP_009873.1
GenBank/EMBL/DDBJ: DAA33856.1 | AY558144 | X59720
Amino Acid Sequence (or in FASTA format)
       1  MQYHSALYVY IYVTFTTIPY KEKPDIISIC FSMLSFVFDF SVRICSRTLE
      51  SFSWSLISSS AFKVVSAFSL AGSCVLASRS SVGIIVSLLL FNFSTCNFVL
     101  FLSAVLIDLF FCTFLPTPTF LPTPFFFMLH LPIFSLLNAL ELLYLIIAGL
     151  HI*                                                   

external links for Fyv5p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BOND SCOP Superfamily YPL+
Ashbya (AGD) BioPIXIE GPMdb (Mass Spec.) YeastGFP
YGOB CYC2008 (complexes) MIPS
YOGY Complexome Pfam domains

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Fyv5p
1) Li D, et al.  (2010) A de novo originated gene depresses budding yeast mating pathway and is repressed by the protein encoded by its antisense strand. Cell Res 20(4):408-20
2) Bianchi MM, et al.  (1999) How to bring orphan genes into functional families. Yeast 15(6):513-26
3) Page N, et al.  (2003) A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer toxin. Genetics 163(3):875-94