POF1/YCL047C Protein Information

Standard Name	Pof1p 1
Systematic Name	Ycl047cp
ORF Classification	Verified
Description	ATPase involved in the protein quality control and filamentation pathways; interacts physically with Kss1p and suppresses the filamentation defect of a kss1 deletion; also interacts with Ubc7p (1, 2)
Name Description	Promoter Of Filamentation 1

Experimental Data
Molecules/cell	830 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	258
Molecular Weight (Da)	29,673
Isoelectric Point (pI)	8

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Pof1p (InterPro)
Physical Interactions	There are 5 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013A5FB \| P25576 MIPS: YCL047C NCBI: 140380 \| 5315 \| 6319802 \| NP_009883.1 GenBank/EMBL/DDBJ: DAA07439.1 \| X59720

Amino Acid Sequence (or in FASTA format)
1 MKKTFEQFRK SNLLFQVLKG PQHLECQKLF VLDSSFNPPH LAHFQLLSQT 51 IKNFKLKDTR SHVLLLLAVN NADKLPKPAS FPTRLEMMCL FADYLQEKLP 101 QSVVSVGLTV FSKFIDKDKI LHEQFVKGCS ADIGYLVGFD TIARIFDEKY 151 YHPLKISDVM ESFMSGSQLY CLARGDCHLS AESQLRYASD ILEGKFEPVI 201 PREWGARIHV MQNDYPALRN VSSSEIRNKL KNGQVESLKD ELPLCIYDYL 251 INNKTIFD*

Amino Acid Sequence (or in FASTA format)

       1  MKKTFEQFRK SNLLFQVLKG PQHLECQKLF VLDSSFNPPH LAHFQLLSQT
      51  IKNFKLKDTR SHVLLLLAVN NADKLPKPAS FPTRLEMMCL FADYLQEKLP
     101  QSVVSVGLTV FSKFIDKDKI LHEQFVKGCS ADIGYLVGFD TIARIFDEKY
     151  YHPLKISDVM ESFMSGSQLY CLARGDCHLS AESQLRYASD ILEGKFEPVI
     201  PREWGARIHV MQNDYPALRN VSSSEIRNKL KNGQVESLKD ELPLCIYDYL
     251  INNKTIFD*

external links for Pof1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	GeneMANIA
YOGY

References cited on this page View Complete Literature Guide for Pof1p

1)	Fasolo J, et al. (2011) Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes. Genes Dev 25(7):767-78
2)	Costa IM, et al. (2011) The promoter of filamentation (POF1) protein from Saccharomyces cerevisiae is an ATPase involved in the protein quality control process. BMC Microbiol 11(1):268
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41