RNQ1/YCL028W Protein Information

Standard Name	Rnq1p 1
Systematic Name	Ycl028wp
ORF Classification	Verified
Description	[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate (1, 2) Also known as: [PIN(+)]
Name Description	Rich in asparagine (N) and glutamine (Q) 1

Experimental Data
Molecules/cell	1140 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	405
Molecular Weight (Da)	42,580
Isoelectric Point (pI)	6.63

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rnq1p (InterPro)
Physical Interactions	There are 86 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006C035 \| P25367 MIPS: YCL028W NCBI: 10383762 \| 171536 \| 19568016 \| 19568018 \| 19568020 \| 19568022 \| 19568024 \| 19568026 \| 19568028 \| 19568030 \| 19568032 \| 19568034 \| 19568036 \| 19568038 \| 46577685 \| NP_009902.2 GenBank/EMBL/DDBJ: DAA07456.1 \| AY028674 \| AY028675 \| AY028676 \| AY028677 \| AY028678 \| AY028679 \| AY028680 \| AY028681 \| AY028682 \| AY028683 \| AY028684 \| AY028685 \| M16717 \| X59720

Amino Acid Sequence (or in FASTA format)
1 MDTDKLISEA ESHFSQGNHA EAVAKLTSAA QSNPNDEQMS TIESLIQKIA 51 GYVMDNRSGG SDASQDRAAG GGSSFMNTLM ADSKGSSQTQ LGKLALLATV 101 MTHSSNKGSS NRGFDVGTVM SMLSGSGGGS QSMGASGLAA LASQFFKSGN 151 NSQGQGQGQG QGQGQGQGQG QGSFTALASL ASSFMNSNNN NQQGQNQSSG 201 GSSFGALASM ASSFMHSNNN QNSNNSQQGY NQSYQNGNQN SQGYNNQQYQ 251 GGNGGYQQQQ GQSGGAFSSL ASMAQSYLGG GQTQSNQQQY NQQGQNNQQQ 301 YQQQGQNYQH QQQGQQQQQG HSSSFSALAS MASSYLGNNS NSNSSYGGQQ 351 QANEYGRPQQ NGQQQSNEYG RPQYGGNQNS NGQHESFNFS GNFSQQNNNG 401 NQNRY*

Amino Acid Sequence (or in FASTA format)

       1  MDTDKLISEA ESHFSQGNHA EAVAKLTSAA QSNPNDEQMS TIESLIQKIA
      51  GYVMDNRSGG SDASQDRAAG GGSSFMNTLM ADSKGSSQTQ LGKLALLATV
     101  MTHSSNKGSS NRGFDVGTVM SMLSGSGGGS QSMGASGLAA LASQFFKSGN
     151  NSQGQGQGQG QGQGQGQGQG QGSFTALASL ASSFMNSNNN NQQGQNQSSG
     201  GSSFGALASM ASSFMHSNNN QNSNNSQQGY NQSYQNGNQN SQGYNNQQYQ
     251  GGNGGYQQQQ GQSGGAFSSL ASMAQSYLGG GQTQSNQQQY NQQGQNNQQQ
     301  YQQQGQNYQH QQQGQQQQQG HSSSFSALAS MASSYLGNNS NSNSSYGGQQ
     351  QANEYGRPQQ NGQQQSNEYG RPQYGGNQNS NGQHESFNFS GNFSQQNNNG
     401  NQNRY*

external links for Rnq1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Rnq1p

1)	Sondheimer N and Lindquist S (2000) Rnq1: an epigenetic modifier of protein function in yeast. Mol Cell 5(1):163-72
2)	Derkatch IL, et al. (2004) Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro. Proc Natl Acad Sci U S A 101(35):12934-9
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41