ILV6/YCL009C Protein Information

Standard Name	Ilv6p 1
Systematic Name	Ycl009cp
ORF Classification	Verified
Description	Regulatory subunit of acetolactate synthase, which catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria (1, 2)
Name Description	IsoLeucine Valine 1

Experimental Data
Molecules/cell	15800 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	309
Molecular Weight (Da)	33,986
Isoelectric Point (pI)	6.51

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ilv6p (InterPro)
Physical Interactions	There are 18 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012D52A \| P25605 MIPS: YCL009C NCBI: 1907135 \| 3041696 \| 6319837 \| NP_009918.1 \| NM_001178658.1 GenBank/EMBL/DDBJ: DAA07472.1 \| X59720
External Classifications	EC: 2.2.1.6 [Acetolactate synthase]

Amino Acid Sequence (or in FASTA format)
1 MLRSLLQSGH RRVVASSCAT MVRCSSSSTS ALAYKQMHRH ATRPPLPTLD 51 TPSWNANSAV SSIIYETPAP SRQPRKQHVL NCLVQNEPGV LSRVSGTLAA 101 RGFNIDSLVV CNTEVKDLSR MTIVLQGQDG VVEQARRQIE DLVPVYAVLD 151 YTNSEIIKRE LVMARISLLG TEYFEDLLLH HHTSTNAGAA DSQELVAEIR 201 EKQFHPANLP ASEVLRLKHE HLNDITNLTN NFGGRVVDIS ETSCIVELSA 251 KPTRISAFLK LVEPFGVLEC ARSGMMALPR TPLKTSTEEA ADEDEKISEI 301 VDISQLPPG*

Amino Acid Sequence (or in FASTA format)

       1  MLRSLLQSGH RRVVASSCAT MVRCSSSSTS ALAYKQMHRH ATRPPLPTLD
      51  TPSWNANSAV SSIIYETPAP SRQPRKQHVL NCLVQNEPGV LSRVSGTLAA
     101  RGFNIDSLVV CNTEVKDLSR MTIVLQGQDG VVEQARRQIE DLVPVYAVLD
     151  YTNSEIIKRE LVMARISLLG TEYFEDLLLH HHTSTNAGAA DSQELVAEIR
     201  EKQFHPANLP ASEVLRLKHE HLNDITNLTN NFGGRVVDIS ETSCIVELSA
     251  KPTRISAFLK LVEPFGVLEC ARSGMMALPR TPLKTSTEEA ADEDEKISEI
     301  VDISQLPPG*

external links for Ilv6p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Ilv6p

1)	Cullin C, et al. (1996) Functional analysis of YCL09C: evidence for a role as the regulatory subunit of acetolactate synthase. Yeast 12(15):1511-8
2)	Pang SS and Duggleby RG (1999) Expression, purification, characterization, and reconstitution of the large and small subunits of yeast acetohydroxyacid synthase. Biochemistry 38(16):5222-31
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41