COS2/YBR302C Protein Information Help

Standard Name Cos2p
Systematic Name Ybr302cp
ORF Classification Verified
Description Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (1, 2)
Name Description COnserved Sequence
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 379
Molecular Weight (Da) 45,165
Isoelectric Point (pI) 8.64

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Cos2p (InterPro)
Transmembrane Domains There are 4 total predicted transmembrane domains (TMHMM)
Physical Interactions There are 2 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000004F952 | P0CX12
MIPS: YBR302C
NCBI: 338817766 | 536767 | 6319779 | 6323503 | NP_009861.1 | NP_013574.1 | NM_001178650.1 | NM_001182495.1
GenBank/EMBL/DDBJ: DAA07417.1 | Z36171
Amino Acid Sequence (or in FASTA format)
 
       1  MKENELKNEK SVDVLSFKQL ESQKIVLPQD LFRSSFTWFC YEIYKSLAFR
      51  IWMLLWLPLS VWWKLSNNCI YPLIVSLLVL FLGPIFVLVI CGLSRKRSLS
     101  KQLIQFCKEI TENTPSSDPH DWEVVAANLN SYLYENNVWN TKYFFFNAMV
     151  CQEAFRTTLL EPFSLKKDKA AKVKSFKDSV PYIEEALGVY FTEVEKQWKL
     201  FNTEKSWSPV GLEDAKLPKE AYRFKLTWFL KRISNIFMLI PFLNFLCCIY
     251  VSRGMCLLLR TLYLGWILFM LVQGFQNIRV LIMSMEHKMQ FLSTIINEQE
     301  SGANGWDEIA RKMNRYLFEK KAWKNEEFFF DGIDCEWFFN HFFYRVLSAK
     351  KSMWPLPLNV ELWPYIKEAQ LSRSEVLLV*

external links for Cos2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS YeastRC Public Image Repository
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Cos2p
1) Spode I, et al.  (2002) ATF/CREB sites present in sub-telomeric regions of Saccharomyces cerevisiae chromosomes are part of promoters and act as UAS/URS of highly conserved COS genes. J Mol Biol 319(2):407-20
2) Despons L, et al.  (2006) An evolutionary scenario for one of the largest yeast gene families. Trends Genet 22(1):10-5