UBX7/YBR273C Protein Information

Standard Name	Ubx7p 1
Systematic Name	Ybr273cp
Alias	Cui3p 2
ORF Classification	Verified
Description	UBX (ubiquitin regulatory X) domain-containing protein; interacts with Cdc48p; UBX7 has a paralog, UBX6, that arose from the whole genome duplication (1, 3)
Name Description	UBiquitin regulatory X 1

Experimental Data
Molecules/cell	2190 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	436
Molecular Weight (Da)	50,030
Isoelectric Point (pI)	6.3

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ubx7p (InterPro)
Physical Interactions	There are 21 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013A29F \| P38349 MIPS: YBR273C NCBI: 536711 \| 586389 \| 6319750 \| NP_009832.1 GenBank/EMBL/DDBJ: DAA07389.1 \| Z36142

Amino Acid Sequence (or in FASTA format)
1 MLEALFRDSV EEAINDSIKE GVVLAVYNTA RDDQWLKSWF KGDDVSLDTL 51 AEHSIWLRLV KDTEQFQLFE QVFPNVVVPS IYLIRAGKIE LIIQGEDDRH 101 WEKLLACIGI KDKKAGESSS RETNPGLARE EKSSRDVHRK NARERIAETT 151 LEIQRREQLK QRKLAEEERE RIIRLVRADR AERKALDETH HRTLDDDKPL 201 DVHDYIKDAQ KLHSSKCVLQ IRMTDGKTLK HEFNSSETLN DVRKWVDVNR 251 TDGDCPYSFH RGIPRVTFKD SDELKTLETL ELTPRSALLL KPLETQNSGL 301 SVTGMEGPSL LGRLYKGFST WWHNDKDPEV TSQREETSKP NRHEVRSSTP 351 LSGAASSSCF QYNNVREPVQ SSAHASPMLT PSGTRYPSET NLTTSRSVSP 401 NVFQFVNNDH QEDPEDPTTF NGNNVHLEKK KDEDKK*

Amino Acid Sequence (or in FASTA format)

       1  MLEALFRDSV EEAINDSIKE GVVLAVYNTA RDDQWLKSWF KGDDVSLDTL
      51  AEHSIWLRLV KDTEQFQLFE QVFPNVVVPS IYLIRAGKIE LIIQGEDDRH
     101  WEKLLACIGI KDKKAGESSS RETNPGLARE EKSSRDVHRK NARERIAETT
     151  LEIQRREQLK QRKLAEEERE RIIRLVRADR AERKALDETH HRTLDDDKPL
     201  DVHDYIKDAQ KLHSSKCVLQ IRMTDGKTLK HEFNSSETLN DVRKWVDVNR
     251  TDGDCPYSFH RGIPRVTFKD SDELKTLETL ELTPRSALLL KPLETQNSGL
     301  SVTGMEGPSL LGRLYKGFST WWHNDKDPEV TSQREETSKP NRHEVRSSTP
     351  LSGAASSSCF QYNNVREPVQ SSAHASPMLT PSGTRYPSET NLTTSRSVSP
     401  NVFQFVNNDH QEDPEDPTTF NGNNVHLEKK KDEDKK*

external links for Ubx7p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ubx7p

1)	Schuberth C, et al. (2004) Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation. EMBO Rep 5(8):818-24
2)	Decottignies A, et al. (2004) Binding of Cdc48p to a ubiquitin-related UBX domain from novel yeast proteins involved in intracellular proteolysis and sporulation. Yeast 21(2):127-39
3)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41