TAE1/YBR261C Protein Information

Standard Name	Tae1p 1
Systematic Name	Ybr261cp
Alias	Ntm1p 2
ORF Classification	Verified
Description	AdoMet-dependent proline methyltransferase; catalyzes the dimethylation of ribosomal proteins Rpl12 and Rps25 at N-terminal proline residues; has a role in protein synthesis; fusion protein localizes to the cytoplasm (1, 2, 3)
Name Description	Translation Associated Element 1

Experimental Data
Molecules/cell	3060 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	232
Molecular Weight (Da)	26,068
Isoelectric Point (pI)	4.96

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Tae1p (InterPro)
Physical Interactions	There are 50 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013A299 \| P38340 MIPS: YBR261C NCBI: 296560 \| 536689 \| 586379 \| 6319738 \| NP_009820.1 \| NM_001178609.1 GenBank/EMBL/DDBJ: DAA07378.1 \| X70529 \| Z36130
External Classifications	EC: 2.1.1.244 [Protein N-terminal methyltransferase]

Amino Acid Sequence (or in FASTA format)
1 MDVPADSHIK YEDAIDYWTD VDATVDGVLG GYGEGTVVPT MDVLGSNNFL 51 RKLKSRMLPQ ENNVKYAVDI GAGIGRVSKT MLHKHAAKID LVEPVKPFIE 101 QMHVELAELK DKGQIGQIYE VGMQDWTPDA GKYWLIWCQW CVGHLPDAEL 151 VAFLKRCIVG LQPNGTIVVK ENNTPTDTDD FDETDSSVTR SDAKFRQIFE 201 EAGLKLIASE RQRGLPRELY PVRMYALKPM PN*

Amino Acid Sequence (or in FASTA format)

       1  MDVPADSHIK YEDAIDYWTD VDATVDGVLG GYGEGTVVPT MDVLGSNNFL
      51  RKLKSRMLPQ ENNVKYAVDI GAGIGRVSKT MLHKHAAKID LVEPVKPFIE
     101  QMHVELAELK DKGQIGQIYE VGMQDWTPDA GKYWLIWCQW CVGHLPDAEL
     151  VAFLKRCIVG LQPNGTIVVK ENNTPTDTDD FDETDSSVTR SDAKFRQIFE
     201  EAGLKLIASE RQRGLPRELY PVRMYALKPM PN*

external links for Tae1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Tae1p

1)	Alamgir M, et al. (2008) Chemical-genetic profile analysis in yeast suggests that a previously uncharacterized open reading frame, YBR261C, affects protein synthesis. BMC Genomics 9:583
2)	Webb KJ, et al. (2010) Identification of protein N-terminal methyltransferases in yeast and humans. Biochemistry 49(25):5225-35
3)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41