RIB5/YBR256C Protein Information

Standard Name	Rib5p 1
Systematic Name	Ybr256cp
ORF Classification	Verified
Description	Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway (2)
Name Description	RIBoflavin biosynthesis 1

Experimental Data
Molecules/cell	7300 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	238
Molecular Weight (Da)	26,196
Isoelectric Point (pI)	4.9

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rib5p (InterPro)
Physical Interactions	There are 6 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000002FB22 \| P38145 MIPS: YBR256C NCBI: 1907247 \| 536679 \| 585862 \| 6319733 \| 639975 \| NP_009815.1 GenBank/EMBL/DDBJ: DAA07373.1 \| X70529 \| Z21621 \| Z36125
External Classifications	EC: 2.5.1.9 [Riboflavin synthase]

Amino Acid Sequence (or in FASTA format)
1 MFTGIVECMG TVLENNPYDD SESGGQGVSI TIGNAGSILT DCHVGDSIAV 51 NGVCLTVTEF NNDSFKVGIS PETIKRSNVA SWIQGTQVNL ERAVSQDVRF 101 GGHYVQGHVD TVANIVSRRP EGNSIIFGFQ LRDQEYFKYI VEKGFICIDG 151 TSLTIIKVDP LSQGGAFYIS MIKHTQDNVI MPLKKIGDEV NIEVDLTGKI 201 IEKQILLTLE NQISKKDSTL NTMISNIIEE KVRNYLNK*

Amino Acid Sequence (or in FASTA format)

       1  MFTGIVECMG TVLENNPYDD SESGGQGVSI TIGNAGSILT DCHVGDSIAV
      51  NGVCLTVTEF NNDSFKVGIS PETIKRSNVA SWIQGTQVNL ERAVSQDVRF
     101  GGHYVQGHVD TVANIVSRRP EGNSIIFGFQ LRDQEYFKYI VEKGFICIDG
     151  TSLTIIKVDP LSQGGAFYIS MIKHTQDNVI MPLKKIGDEV NIEVDLTGKI
     201  IEKQILLTLE NQISKKDSTL NTMISNIIEE KVRNYLNK*

external links for Rib5p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	GeneMANIA
YOGY

References cited on this page View Complete Literature Guide for Rib5p

1)	Oltmanns O and Bacher A (1972) Biosynthesis of riboflavine in Saccharomyces cerevisiae: the role of genes rib 1 and rib 7. J Bacteriol 110(3):818-22
2)	Santos MA, et al. (1995) Riboflavin biosynthesis in Saccharomyces cerevisiae. Cloning, characterization, and expression of the RIB5 gene encoding riboflavin synthase. J Biol Chem 270(1):437-44
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41