ARC40/YBR234C Protein Information

Standard Name	Arc40p 1
Systematic Name	Ybr234cp
ORF Classification	Verified
Description	Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches (1, 2)
Name Description	ARp2/3 Complex subunit 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	384
Molecular Weight (Da)	42,475
Isoelectric Point (pI)	7.03

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Arc40p (InterPro)
Physical Interactions	There are 99 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00000531DA \| P38328 MIPS: YBR234C NCBI: 51012967 \| 536635 \| 586351 \| 6319711 \| NP_009793.1 GenBank/EMBL/DDBJ: DAA07350.1 \| AY692758 \| Z36103

Amino Acid Sequence (or in FASTA format)
1 MSFSNSKDKS VVAVYKLVKA PIYSHCFSQD KSILAVTCET DCLVYRVSNN 51 TPPVLFATLK DHDKTITAVD ISIHGRIVTC SQDRNAYVWE PLSDGTYKPT 101 LVLLRINRAA TSVTWAPNGY KFAVGSSARI IAVCYYEHEN NWWVSKHIKK 151 PIKSTINCLS WHANGVLLAA GGTDGFMRVF SGFIKGLDSK ESVAGSPWGQ 201 KFPFGCLIRE WYQGSYIHDV EWRSQMERIA YVAHDGTLNV VDYQSPVQSV 251 NAPEGLPYRS LVWINDHEIV CGGYSCHPVL FSEASEGWKF AKNLDKSDNN 301 KSSALTASGN TDELSGNNDE SSTFGISALR KFKELDLKGK VSTDVQESAH 351 ENAIVELRPF AESNGQITQV SSCGLDGKIV IYTI*

Amino Acid Sequence (or in FASTA format)

       1  MSFSNSKDKS VVAVYKLVKA PIYSHCFSQD KSILAVTCET DCLVYRVSNN
      51  TPPVLFATLK DHDKTITAVD ISIHGRIVTC SQDRNAYVWE PLSDGTYKPT
     101  LVLLRINRAA TSVTWAPNGY KFAVGSSARI IAVCYYEHEN NWWVSKHIKK
     151  PIKSTINCLS WHANGVLLAA GGTDGFMRVF SGFIKGLDSK ESVAGSPWGQ
     201  KFPFGCLIRE WYQGSYIHDV EWRSQMERIA YVAHDGTLNV VDYQSPVQSV
     251  NAPEGLPYRS LVWINDHEIV CGGYSCHPVL FSEASEGWKF AKNLDKSDNN
     301  KSSALTASGN TDELSGNNDE SSTFGISALR KFKELDLKGK VSTDVQESAH
     351  ENAIVELRPF AESNGQITQV SSCGLDGKIV IYTI*

external links for Arc40p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Arc40p

1)	Winter DC, et al. (1999) Genetic dissection of the budding yeast Arp2/3 complex: a comparison of the in vivo and structural roles of individual subunits. Proc Natl Acad Sci U S A 96(13):7288-93
2)	Pan F, et al. (2004) ARPC1/Arc40 mediates the interaction of the actin-related protein 2 and 3 complex with Wiskott-Aldrich syndrome protein family activators. J Biol Chem 279(52):54629-36