MCX1/YBR227C Protein Information

Standard Name	Mcx1p
Systematic Name	Ybr227cp
ORF Classification	Verified
Description	Mitochondrial matrix protein; putative ATP-binding chaperone with non-proteolytic function; similar to bacterial ClpX proteins (1)
Name Description	Mitochondrial ClpX 1

Experimental Data
Molecules/cell	10900 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	520
Molecular Weight (Da)	57,945
Isoelectric Point (pI)	7.8

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mcx1p (InterPro)
Physical Interactions	There are 4 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012EDFA \| P38323 MIPS: YBR227C NCBI: 536622 \| 586344 \| 6319704 \| NP_009786.1 \| NM_001178575.1 GenBank/EMBL/DDBJ: DAA07342.1 \| Z36096

Amino Acid Sequence (or in FASTA format)
1 MLKSASQNFF RAYSSRIGRY AATASGKLAQ SRLSNIPTPK ALKKFLDEYI 51 VGQEIGKKVL SVAVYNHYLR INDKQKKGEL QRQRELMERE KIADDRDEPI 101 FSGNSESKAG WRNLQRQFNL AGREVDEDLE LSKSNVLVVG PSGSGKTLLA 151 TTLAKILNVP IAITDCTQLT QAGYIGEDVE VCIERLLVNA EFDVARAEKG 201 IIVLDEIDKL AKPAASIGTK DVSGEGVQQS LLKIIEGHKV EITVKRPVKH 251 DIDGQKNQTT TKKDEVFVVD TSNILFMIMG AFVGLDKHIV KRIEDMKKIQ 301 KAGESVESSN SKEVEKERAK KFRFSNTLEQ VELDNGKKVC ALDLTTPTDL 351 VSFGLIPELI GRVPIITALQ PLQRDDLFHI LKEPKNALLD QYEYIFKQFG 401 VRLCVTQKAL KKVAQFALKE GTGARGLRGI MERLLLNVNY DCPGSNIAYV 451 LIDEATVDSL QETEHSLASQ VDVKYYSGDE KDSLIRDVSE EDKKLGVMLE 501 KELGHSANIH TPTIPKRSLT *

Amino Acid Sequence (or in FASTA format)

       1  MLKSASQNFF RAYSSRIGRY AATASGKLAQ SRLSNIPTPK ALKKFLDEYI
      51  VGQEIGKKVL SVAVYNHYLR INDKQKKGEL QRQRELMERE KIADDRDEPI
     101  FSGNSESKAG WRNLQRQFNL AGREVDEDLE LSKSNVLVVG PSGSGKTLLA
     151  TTLAKILNVP IAITDCTQLT QAGYIGEDVE VCIERLLVNA EFDVARAEKG
     201  IIVLDEIDKL AKPAASIGTK DVSGEGVQQS LLKIIEGHKV EITVKRPVKH
     251  DIDGQKNQTT TKKDEVFVVD TSNILFMIMG AFVGLDKHIV KRIEDMKKIQ
     301  KAGESVESSN SKEVEKERAK KFRFSNTLEQ VELDNGKKVC ALDLTTPTDL
     351  VSFGLIPELI GRVPIITALQ PLQRDDLFHI LKEPKNALLD QYEYIFKQFG
     401  VRLCVTQKAL KKVAQFALKE GTGARGLRGI MERLLLNVNY DCPGSNIAYV
     451  LIDEATVDSL QETEHSLASQ VDVKYYSGDE KDSLIRDVSE EDKKLGVMLE
     501  KELGHSANIH TPTIPKRSLT *

external links for Mcx1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
YGOB	CYC2008 (complexes)	Pfam domains
YOGY	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Mcx1p

1)	van Dyck L, et al. (1998) Mcx1p, a ClpX homologue in mitochondria of Saccharomyces cerevisiae. FEBS Lett 438(3):250-4
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41