KTR4/YBR199W Protein Information

Standard Name	Ktr4p
Systematic Name	Ybr199wp
ORF Classification	Verified
Description	Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family (1)
Name Description	Kre Two Related 2

Experimental Data
Molecules/cell	5240 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	464
Molecular Weight (Da)	54,556
Isoelectric Point (pI)	4.56

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ktr4p (InterPro)
Transmembrane Domains	There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 7 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012E11E \| P38131 MIPS: YBR199W NCBI: 1870115 \| 311675 \| 398365437 \| 51013247 \| 536571 \| 585377 \| NP_009758.3 GenBank/EMBL/DDBJ: DAA07315.1 \| AY692898 \| Z21487 \| Z36068 \| Z36069
External Classifications	EC: 2.4.1.- [Hexosyltransferases] EC: 2.4.1.131 [GDP-Man:Man(3)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase]

Amino Acid Sequence (or in FASTA format)
1 MRFLSKRILK PVLSVIILIS IAVTVVLYFL TANENYLQAV KDSAKSQYAS 51 LRESYKSITG KTESADELPD HDAEVLDSIM DRLHEPLYEK DTFDPNEVLA 101 ENKQLYEEFL LQEISEPKVD NLVRSGDPLA GKAKGTILSL VRNSDLEDII 151 SSIQQLEEEY NKNFGYPYTF LNDEEFTDEF KDGIKSILPK DRVVEFGTIG 201 PDNWNMPDSI DRERYDQEMD KMSKENIQYA EVESYHNMCR FYSKEFYHHP 251 LLSKYKYVWR LEPNVNFYCK INYDVFQFMN KNDKIYGFVL NLYDSPQTIE 301 TLWTSTMDFV EEHPNYLNVN GAFAWLKDNS QNPKNYDYTQ GYSTCHFWTN 351 FEIVDLDFLR SEPYEKYMQY LEEKGGFYYE RWGDAPVRSL ALALFADKSS 401 IHWFRDIGYH HTPYTNCPTC PADSDRCNGN CVPGKFTPWS DLDNQNCQAT 451 WIRHSMSEEE LEMY*

Amino Acid Sequence (or in FASTA format)

       1  MRFLSKRILK PVLSVIILIS IAVTVVLYFL TANENYLQAV KDSAKSQYAS
      51  LRESYKSITG KTESADELPD HDAEVLDSIM DRLHEPLYEK DTFDPNEVLA
     101  ENKQLYEEFL LQEISEPKVD NLVRSGDPLA GKAKGTILSL VRNSDLEDII
     151  SSIQQLEEEY NKNFGYPYTF LNDEEFTDEF KDGIKSILPK DRVVEFGTIG
     201  PDNWNMPDSI DRERYDQEMD KMSKENIQYA EVESYHNMCR FYSKEFYHHP
     251  LLSKYKYVWR LEPNVNFYCK INYDVFQFMN KNDKIYGFVL NLYDSPQTIE
     301  TLWTSTMDFV EEHPNYLNVN GAFAWLKDNS QNPKNYDYTQ GYSTCHFWTN
     351  FEIVDLDFLR SEPYEKYMQY LEEKGGFYYE RWGDAPVRSL ALALFADKSS
     401  IHWFRDIGYH HTPYTNCPTC PADSDRCNGN CVPGKFTPWS DLDNQNCQAT
     451  WIRHSMSEEE LEMY*

external links for Ktr4p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ktr4p

1)	Lussier M, et al. (1996) Functional characterization of the YUR1, KTR1, and KTR2 genes as members of the yeast KRE2/MNT1 mannosyltransferase gene family. J Biol Chem 271(18):11001-8
2)	Lussier M, et al. (1997) Completion of the Saccharomyces cerevisiae genome sequence allows identification of KTR5, KTR6 and KTR7 and definition of the nine-membered KRE2/MNT1 mannosyltransferase gene family in this organism. Yeast 13(3):267-74
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41