ECM31/YBR176W Protein Information Help

Standard Name Ecm31p 1
Systematic Name Ybr176wp
ORF Classification Verified
Description Ketopantoate hydroxymethyltransferase; required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate (1, 2, 3)
Name Description ExtraCellular Mutant 1
Experimental Data
Molecules/cell 1420 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 312
Molecular Weight (Da) 34,465
Isoelectric Point (pI) 8.12

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ecm31p (InterPro)
Physical Interactions There are 9 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013128B | P38122
MIPS: YBR176W
NCBI: 398365289 | 536525 | 585643 | NP_009735.3 | NM_001178524.3
GenBank/EMBL/DDBJ: CAA85137.1 | DAA07291.1 | Z36045
External Classifications EC: 2.1.2.11 [3-methyl-2-oxobutanoate hydroxymethyltransferase]
Amino Acid Sequence (or in FASTA format)
       1  MNIMKRQLCT SSKRFFSTAK NVVKYNTIQD IRNKYFTGTP LSMCTAYDFI
      51  TATWVNKANC DLLLVGDSLA MTSLGYDSTI TLSLNEFKYH VASVCRAEGS
     101  SMVVVDMPFG TFESGISDGL KNAIDIMKLD SKVTSVKVEV GSYTKDKYAM
     151  KFIEELCSRG IPVMAHIGLT PQKVHSLGGY KVQGSKSLLQ MQELYETAMQ
     201  LQKIGCWSIL IECVPHKMAQ FITSKLSVPT IGIGAGNGTS GQVLVISDLL
     251  GMQGDSVPKF VKQAVNMTDI ATQGLKEYIA SVEDRTFPER GTHTFKVKED
     301  LWNEFLSSIN EK*                                        

external links for Ecm31p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) CYC2008 (complexes) MIPS YeastGFP
Candida (CGD) Complexome Pfam domains YeastRC Public Image Repository
YGOB DIP YeastRC Structure Prediction (Seattle)
YOGY GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Ecm31p
1) Lussier M, et al.  (1997) Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics 147(2):435-50
2) Entian KD, et al.  (1999) Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 262(4-5):683-702
3) White WH, et al.  (2001) Saccharomyces cerevisiae is capable of de Novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine. J Biol Chem 276(14):10794-800
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41