TYR1/YBR166C Protein Information Help

Standard Name Tyr1p
Systematic Name Ybr166cp
ORF Classification Verified
Description Prephenate dehydrogenase involved in tyrosine biosynthesis, expression is dependent on phenylalanine levels (1)
Name Description TYRosine requiring
Experimental Data
Molecules/cell 2180 2
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 452
Molecular Weight (Da) 50,923
Isoelectric Point (pI) 6.57

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Tyr1p (InterPro)
Physical Interactions There are 8 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000004BBD9 | P20049
MIPS: YBR166C
NCBI: 536506 | 586139 | 6319643 | NP_009725.1
GenBank/EMBL/DDBJ: DAA07282.1 | Z36035
External Classifications EC: 1.3.1.13 [Prephenate dehydrogenase (NADP(+))]
Amino Acid Sequence (or in FASTA format)
 
       1  MVSEDKIEQW KATKVIGIIG LGDMGLLYAN KFTDAGWGVI CCDREEYYDE
      51  LKEKYASAKF ELVKNGHLVS RQSDYIIYSV EASNISKIVA TYGPSSKVGT
     101  IVGGQTSCKL PEIEAFEKYL PKDCDIITVH SLHGPKVNTE GQPLVIINHR
     151  SQYPESFEFV NSVMACLKSK QVYLTYEEHD KITADTQAVT HAAFLSMGSA
     201  WAKIKIYPWT LGVNKWYGGL ENVKVNISLR IYSNKWHVYA GLAITNPSAH
     251  QQILQYATSA TELFSLMIDN KEQELTDRLL KAKQFVFGKH TGLLLLDDTI
     301  LEKYSLSKSS IGNSNNCKPV PNSHLSLLAI VDSWFQLGID PYDHMICSTP
     351  LFRIFLGVSE YLFLKPGLLE QTIDAAIHDK SFIKDDLEFV ISAREWSSVV
     401  SFANFDIYKK QFQSVQKFFE PMLPEANLIG NEMIKTILSH SSDRSAAEKR
     451  NT*

external links for Tyr1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Tyr1p
1) Mannhaupt G, et al.  (1989) Characterization of the prephenate dehydrogenase-encoding gene, TYR1, from Saccharomyces cerevisiae. Gene 85(2):303-11
2) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41