TBS1/YBR150C Protein Information Help

Standard Name Tbs1p 1
Systematic Name Ybr150cp
ORF Classification Verified
Description Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; TBS1 has a paralog, HAL9, that arose from the whole genome duplication (2, 3, 4, 5)
Name Description ThiaBendazole Sensitive 1
Experimental Data
Molecules/cell 573 6
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,094
Molecular Weight (Da) 126,902
Isoelectric Point (pI) 5.15

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Tbs1p (InterPro)
Physical Interactions There are 9 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013A1A4 | P38114
MIPS: YBR150C
NCBI: 1870111 | 536476 | 586293 | 6319626 | NP_009708.1
GenBank/EMBL/DDBJ: DAA07265.1 | Z36019 | Z36020
Amino Acid Sequence (or in FASTA format)
 
       1  MNMDSGITSS HGSMDKTQKQ SSEWAANQKH NQRVENTRVL MGPAVPAMPP
      51  VPSNFPPVPT GTIMSPQLSP FPDHRLRHHP LAHMMPADKN FLAYNMESFK
     101  SRVTKACDYC RKRKIRCTEI EPISGKCRNC IKYNKDCTFH FHEELKRRRE
     151  EALNNKGNGK SVKKPRLDKE NKFKDENFDI AVRSRNTSST DSSPKLHTNL
     201  SQEYIGVSAG KSASDKEDTW PDFVPIDRTV LEKIELNHTK VAGKVFVLEE
     251  ICKNMKGTIE KLAEKSKIDV IDKEYMKRPK RKQYSKALLT KQKMFHFRQN
     301  VLSHLTDEEF LSPINEMFTT TFKYSILQTK LVLDFSFRSA SSPSSDNILY
     351  PLPRLAIAKR LLKNIKCPSL ASLLHIVDVD QCLQFADVHF DPAKGRLTSS
     401  QAFLLNICLC LGATVTNFEE KQELVDEDNH ETYYFEKFEL WRLRSFTFLN
     451  SVYYYHKLSV ARADMTALKA LLLLAKFAQQ KISASSAVKV LSVAIKVALD
     501  LRLNLHSTYE DLELDEIIKR RRLWCYCFST DKFFSVVLSR PPFLKEENTD
     551  VLTDESYVEL FRDKILPNLS IKYDDSKLEG VKDIVSVVNL LANHLEYVPY
     601  IQSYFLSRLS LIESQIYYSC FSIRTTLDDT LDEIIENVLE NQKALDRMRD
     651  DLPTILSLEN YKENMRILSL DSSKLDFEVS CCTTILLHLR WYHQKITLSL
     701  FVISIIGDNL DQRESSRHDI AEIIRRSRLD FKRNCIEVLN ILKDFEYYPT
     751  VQNEFLYFSL TTVFSMFLYL SEIMVNDEHA METGYIIGLL RDTHTRMLGS
     801  EERCLSVHNL KWQTSLFFYT FFLRSTMEKF NLTSKYAKFY AFDSNYYEGV
     851  LNRLVKHTRE SKDDMVELLK TSFINKEKMA AFGSFVTEDQ EKMEVSFNIF
     901  NEITIQDLNF LQFSSIPKLW ENKTLEPGEE YHHSNGTNTD NNETTGADDT
     951  DDNNNNNNNN NKNGNNSSST INNNNNNYSN SNNNDNDNNI NDDDDDDDDD
    1001  DDDDDDDDDD DDNDDDYSNN GADDDEEDDD YDRSLFPTGL ASLLDASYPE
    1051  RTANDYRDEN EQSNKLFEKI EGHLEHGVFF YDRDFFFKNV CVKM*

external links for Tbs1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS YeastRC Public Image Repository
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Tbs1p
1) Entian KD, et al.  (1999) Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 262(4-5):683-702
2) Feldmann H, et al.  (1994) Complete DNA sequence of yeast chromosome II. EMBO J 13(24):5795-809
3) Sickmann A, et al.  (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
6) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41