ADH5/YBR145W Protein Information

Standard Name	Adh5p
Systematic Name	Ybr145wp
ORF Classification	Verified
Description	Alcohol dehydrogenase isoenzyme V; involved in ethanol production; ADH5 has a paralog, ADH1, that arose from the whole genome duplication (1, 2)
Name Description	Alcohol DeHydrogenase

Experimental Data
Molecules/cell	1310 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	351
Molecular Weight (Da)	37,648
Isoelectric Point (pI)	6.34

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Adh5p (InterPro)
Physical Interactions	There are 3 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000125588 \| P38113 MIPS: YBR145W NCBI: 398365069 \| 536448 \| 584729 \| NP_009703.3 GenBank/EMBL/DDBJ: DAA07260.1 \| Z36014
External Classifications	EC: 1.1.1.1 [Alcohol dehydrogenase] EC: 1.1.1.190 [Indole-3-acetaldehyde reductase (NADH)]

Amino Acid Sequence (or in FASTA format)
1 MPSQVIPEKQ KAIVFYETDG KLEYKDVTVP EPKPNEILVH VKYSGVCHSD 51 LHAWHGDWPF QLKFPLIGGH EGAGVVVKLG SNVKGWKVGD FAGIKWLNGT 101 CMSCEYCEVG NESQCPYLDG TGFTHDGTFQ EYATADAVQA AHIPPNVNLA 151 EVAPILCAGI TVYKALKRAN VIPGQWVTIS GACGGLGSLA IQYALAMGYR 201 VIGIDGGNAK RKLFEQLGGE IFIDFTEEKD IVGAIIKATN GGSHGVINVS 251 VSEAAIEAST RYCRPNGTVV LVGMPAHAYC NSDVFNQVVK SISIVGSCVG 301 NRADTREALD FFARGLIKSP IHLAGLSDVP EIFAKMEKGE IVGRYVVETS 351 K*

Amino Acid Sequence (or in FASTA format)

       1  MPSQVIPEKQ KAIVFYETDG KLEYKDVTVP EPKPNEILVH VKYSGVCHSD
      51  LHAWHGDWPF QLKFPLIGGH EGAGVVVKLG SNVKGWKVGD FAGIKWLNGT
     101  CMSCEYCEVG NESQCPYLDG TGFTHDGTFQ EYATADAVQA AHIPPNVNLA
     151  EVAPILCAGI TVYKALKRAN VIPGQWVTIS GACGGLGSLA IQYALAMGYR
     201  VIGIDGGNAK RKLFEQLGGE IFIDFTEEKD IVGAIIKATN GGSHGVINVS
     251  VSEAAIEAST RYCRPNGTVV LVGMPAHAYC NSDVFNQVVK SISIVGSCVG
     301  NRADTREALD FFARGLIKSP IHLAGLSDVP EIFAKMEKGE IVGRYVVETS
     351  K*

external links for Adh5p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Adh5p

1)	Smith MG, et al. (2004) Microbial synergy via an ethanol-triggered pathway. Mol Cell Biol 24(9):3874-84
2)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41