RAD16/YBR114W Protein Information Help

Standard Name Rad16p 1
Systematic Name Ybr114wp
Alias Pso5p
ORF Classification Verified
Description Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad7p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex (2, 3)
Name Description RADiation sensitive
Experimental Data
Molecules/cell 358 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 790
Molecular Weight (Da) 91,430
Isoelectric Point (pI) 8.27

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rad16p (InterPro)
Physical Interactions There are 59 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00000531CA | P31244
MIPS: YBR114W
NCBI: 172320 | 3551 | 400920 | 476069 | 487900 | 536453 | 6319590 | NP_009672.1
GenBank/EMBL/DDBJ: DAA07233.1 | M83553 | M86929 | X66247 | X78993 | Z35983
External Classifications EC: 3.6.1.- [Hydrolases acting on acid anhydrides in phosphorous-containing anhydrides]
Amino Acid Sequence (or in FASTA format)
 
       1  MQEGGFIRRR RTRSTKKSVN YNELSDDDTA VKNSKTLQLK GNSENVNDSQ
      51  DEEYRDDATL VKSPDDDDKD FIIDLTGSDK ERTATDENTH AIKNDNDEII
     101  EIKEERDVSD DDEPLTKKRK TTARKKKKKT STKKKSPKVT PYERNTLRLY
     151  EHHPELRNVF TDLKNAPPYV PQRSKQPDGM TIKLLPFQLE GLHWLISQEE
     201  SIYAGGVLAD EMGMGKTIQT IALLMNDLTK SPSLVVAPTV ALMQWKNEIE
     251  QHTKGQLKIY IYHGASRTTD IKDLQGYDVV LTTYAVLESV FRKQNYGFRR
     301  KNGLFKQPSV LHNIDFYRVI LDEAHNIKDR QSNTARAVNN LKTQKRWCLS
     351  GTPLQNRIGE MYSLIRFLNI NPFTKYFCTK CDCASKDWKF TDRMHCDHCS
     401  HVIMQHTNFF NHFMLKNIQK FGVEGPGLES FNNIQTLLKN IMLRRTKVER
     451  ADDLGLPPRI VTVRRDFFNE EEKDLYRSLY TDSKRKYNSF VEEGVVLNNY
     501  ANIFTLITRM RQLADHPDLV LKRLNNFPGD DIGVVICQLC NDEAEEPIES
     551  KCHHKFCRLC IKEYVESFME NNNKLTCPVC HIGLSIDLSQ PALEVDLDSF
     601  KKQSIVSRLN MSGKWQSSTK IEALVEELYK LRSNKRTIKS IVFSQFTSML
     651  DLVEWRLKRA GFQTVKLQGS MSPTQRDETI KYFMNNIQCE VFLVSLKAGG
     701  VALNLCEASQ VFILDPWWNP SVEWQSGDRV HRIGQYRPVK ITRFCIEDSI
     751  EARIIELQEK KANMIHATIN QDEAAISRLT PADLQFLFNN *

external links for Rad16p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Rad16p
1) Game, J.  (1989) Personal Communication, Mortimer Map Edition 10
2) Prakash S and Prakash L  (2000) Nucleotide excision repair in yeast. Mutat Res 451(1-2):13-24
3) Gillette TG, et al.  (2006) Distinct functions of the ubiquitin-proteasome pathway influence nucleotide excision repair. EMBO J 25(11):2529-38
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41