TEC1/YBR083W Protein Information Help

Standard Name Tec1p 1
Systematic Name Ybr083wp
Alias Roc1p 2
ORF Classification Verified
Description Transcription factor targeting filamentation genes and Ty1 expression; Ste12p activation of most filamentation gene promoters depends on Tec1p and Tec1p transcriptional activity is dependent on its association with Ste12p; binds to TCS elements upstream of filamentation genes, which are regulated by Tec1p/Ste12p/Dig1p complex; competes with Dig2p for binding to Ste12p/Dig1p; positive regulator of chronological life span; TEA/ATTS DNA-binding domain family member (1, 3, 4, 5, 6)
Name Description Transposon Enhancement Control 1
Experimental Data
Molecules/cell 530 7
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 486
Molecular Weight (Da) 55,157
Isoelectric Point (pI) 7.71

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Tec1p (InterPro)
Physical Interactions There are 38 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000136B88 | P18412
MIPS: YBR083W
NCBI: 135565 | 172882 | 398364681 | 536346 | NP_009639.3
GenBank/EMBL/DDBJ: DAA07202.1 | M32797 | Z35952
Amino Acid Sequence (or in FASTA format)
 
       1  MSLKEDDFGK DNSRNIESYT GRIFDVYIQK DSYSQSALDD MFPEAVVSTA
      51  ACVKNEAEDN INLIDTHPQF ELVNTGLGAK SDDLKSPSAK ATFTDKQRKN
     101  EVPNISVSNY FPGQSSETSS TTESWTIGCD KWSEKVEEAF LEALRLIMKN
     151  GTTKIKIRNA NFGRNELISL YIKHKTNEFR TKKQISSHIQ VWKKTIQNKI
     201  KDSLTLSSKE KELLHLIEHG AEQTTENSNL FYDIFEEIID SLPSVSDSGS
     251  LTPKNLYVSN NSSGLSVHSK LLTPITASNE KKIENFIKTN AASQAKTPLI
     301  YAKHIYENID GYKCVPSKRP LEQLSPTELH QGDRPNKASF SNKKAILESA
     351  KKIEIEQRKI INKYQRISRI QEHESNPEFS SNSNSGSEYE SEEEVVPRSA
     401  TVTQLQSRPV PYYKNNGMPY SLSKVRGRPM YPRPAEDAYN ANYIQGLPQY
     451  QTSYFSQLLL SSPQHYEHSP HQRNFTPSNQ SHGNFY*

external links for Tec1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
YGOB BioPIXIE MIPS YeastGFP
YOGY CYC2008 (complexes) Pfam domains YeastRC Public Image Repository

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Tec1p
1) Laloux I, et al.  (1990) TEC1, a gene involved in the activation of Ty1 and Ty1-mediated gene expression in Saccharomyces cerevisiae: cloning and molecular analysis. Mol Cell Biol 10(7):3541-50
2) Dubois E, et al.  (1982) Expression of the ROAM mutations in Saccharomyces cerevisiae: involvement of trans-acting regulatory elements and relation with the Ty1 transcription. EMBO J 1(9):1133-9
3) Kohler T, et al.  (2002) Dual role of the Saccharomyces cerevisiae TEA/ATTS family transcription factor Tec1p in regulation of gene expression and cellular development. Eukaryot Cell 1(5):673-86
4) Zeitlinger J, et al.  (2003) Program-specific distribution of a transcription factor dependent on partner transcription factor and MAPK signaling. Cell 113(3):395-404
5) Chou S, et al.  (2006) Regulation of mating and filamentation genes by two distinct Ste12 complexes in Saccharomyces cerevisiae. Mol Cell Biol 26(13):4794-805
6) Bruckner S, et al.  (2011) The TEA transcription factor Tec1 links TOR and MAPK pathways to coordinate yeast development. Genetics 189(2):479-94
7) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41