ZTA1/YBR046C Protein Information

Standard Name	Zta1p
Systematic Name	Ybr046cp
ORF Classification	Verified
Description	NADPH-dependent quinone reductase, GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin (1, 2, 3)
Name Description	ZeTA-crystallin

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	334
Molecular Weight (Da)	37,018
Isoelectric Point (pI)	9.46

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Zta1p (InterPro)
Physical Interactions	There are 6 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000132E64 \| P38230 MIPS: YBR046C NCBI: 374977578 \| 374977579 \| 374977580 \| 374977581 \| 374977582 \| 374977583 \| 45269623 \| 536274 \| 586489 \| 6319520 \| NP_009602.1 \| NM_001178394.1 GenBank/EMBL/DDBJ: DAA07166.1 \| AY557866 \| Z35915
External Classifications	EC: 1.6.5.5 [NADPH:quinone reductase]

Amino Acid Sequence (or in FASTA format)
1 MKCTIPEQQK VILIDEIGGY DVIKYEDYPV PSISEEELLI KNKYTGVNYI 51 ESYFRKGIYP CEKPYVLGRE ASGTVVAKGK GVTNFEVGDQ VAYISNSTFA 101 QYSKISSQGP VMKLPKGTSD EELKLYAAGL LQVLTALSFT NEAYHVKKGD 151 YVLLFAAAGG VGLILNQLLK MKGAHTIAVA STDEKLKIAK EYGAEYLINA 201 SKEDILRQVL KFTNGKGVDA SFDSVGKDTF EISLAALKRK GVFVSFGNAS 251 GLIPPFSITR LSPKNITLVR PQLYGYIADP EEWKYYSDEF FGLVNSKKLN 301 IKIYKTYPLR DYRTAAADIE SRKTVGKLVL EIPQ*

Amino Acid Sequence (or in FASTA format)

       1  MKCTIPEQQK VILIDEIGGY DVIKYEDYPV PSISEEELLI KNKYTGVNYI
      51  ESYFRKGIYP CEKPYVLGRE ASGTVVAKGK GVTNFEVGDQ VAYISNSTFA
     101  QYSKISSQGP VMKLPKGTSD EELKLYAAGL LQVLTALSFT NEAYHVKKGD
     151  YVLLFAAAGG VGLILNQLLK MKGAHTIAVA STDEKLKIAK EYGAEYLINA
     201  SKEDILRQVL KFTNGKGVDA SFDSVGKDTF EISLAALKRK GVFVSFGNAS
     251  GLIPPFSITR LSPKNITLVR PQLYGYIADP EEWKYYSDEF FGLVNSKKLN
     301  IKIYKTYPLR DYRTAAADIE SRKTVGKLVL EIPQ*

external links for Zta1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	GeneMANIA
YOGY

References cited on this page View Complete Literature Guide for Zta1p

1)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
2)	Fernandez MR, et al. (2007) Human and yeast zeta-crystallins bind AU-rich elements in RNA. Cell Mol Life Sci 64(11):1419-27
3)	Porte S, et al. (2009) MDR quinone oxidoreductases: the human and yeast zeta-crystallins. Chem Biol Interact 178(1-3):288-94