ZTA1/YBR046C Protein Information Help

Standard Name Zta1p
Systematic Name Ybr046cp
ORF Classification Verified
Description NADPH-dependent quinone reductase; GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin (1, 2, 3)
Name Description ZeTA-crystallin
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 334
Molecular Weight (Da) 37,018
Isoelectric Point (pI) 9.46

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Zta1p (InterPro)
Physical Interactions There are 7 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000132E64 | P38230
MIPS: YBR046C
NCBI: 45269623 | 536274 | 586489 | 6319520 | NP_009602.1 | NM_001178394.1
GenBank/EMBL/DDBJ: AAS56192.1 | CAA84988.1 | DAA07166.1 | AY557866 | Z35915
External Classifications EC: 1.6.5.5 [NADPH:quinone reductase]
Amino Acid Sequence (or in FASTA format)
       1  MKCTIPEQQK VILIDEIGGY DVIKYEDYPV PSISEEELLI KNKYTGVNYI
      51  ESYFRKGIYP CEKPYVLGRE ASGTVVAKGK GVTNFEVGDQ VAYISNSTFA
     101  QYSKISSQGP VMKLPKGTSD EELKLYAAGL LQVLTALSFT NEAYHVKKGD
     151  YVLLFAAAGG VGLILNQLLK MKGAHTIAVA STDEKLKIAK EYGAEYLINA
     201  SKEDILRQVL KFTNGKGVDA SFDSVGKDTF EISLAALKRK GVFVSFGNAS
     251  GLIPPFSITR LSPKNITLVR PQLYGYIADP EEWKYYSDEF FGLVNSKKLN
     301  IKIYKTYPLR DYRTAAADIE SRKTVGKLVL EIPQ*                

external links for Zta1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) CYC2008 (complexes) MIPS YeastGFP
Candida (CGD) Complexome Pfam domains YeastRC Public Image Repository
YGOB GeneMANIA YeastRC Structure Prediction (Seattle)
YOGY IMP

References cited on this page View Complete Literature Guide for Zta1p
1) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
2) Fernandez MR, et al.  (2007) Human and yeast zeta-crystallins bind AU-rich elements in RNA. Cell Mol Life Sci 64(11):1419-27
3) Porte S, et al.  (2009) MDR quinone oxidoreductases: the human and yeast zeta-crystallins. Chem Biol Interact 178(1-3):288-94