FIG1/YBR040W Protein Information

Standard Name	Fig1p 1
Systematic Name	Ybr040wp
ORF Classification	Verified
Description	Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating (1, 2)
Name Description	Factor-Induced Gene 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	298
Molecular Weight (Da)	33,775
Isoelectric Point (pI)	10.3

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Fig1p (InterPro)
Transmembrane Domains	There are 4 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 2 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012A7A8 \| P38224 MIPS: YBR040W NCBI: 45269619 \| 45719804 \| 45719806 \| 45719808 \| 45719810 \| 45719812 \| 45719814 \| 45719816 \| 45719818 \| 45719820 \| 45719822 \| 45719824 \| 45719826 \| 45719828 \| 45719830 \| 45719832 \| 45719834 \| 45719836 \| 45719838 \| 45719840 \| 45719842 \| 536262 \| 586483 \| 6319514 \| NP_009596.1 \| NM_001178388.1 GenBank/EMBL/DDBJ: DAA07160.1 \| AJ585600 \| AJ585601 \| AJ585602 \| AJ585603 \| AJ585604 \| AJ585605 \| AJ585606 \| AJ585607 \| AJ585608 \| AJ585609 \| AJ585610 \| AJ585611 \| AJ585612 \| AJ585613 \| AJ585614 \| AJ585615 \| AJ585616 \| AJ585617 \| AJ585618 \| AJ585619 \| AY557864 \| Z35909

Amino Acid Sequence (or in FASTA format)
1 MVAISMIWFF TKRMPRIFAL AFNLISIFLL IFLLIGCYNP SNQSTFLVKY 51 KFDDNSPFYT IIEKSYEKSN TTLGLEEVII RSGYMGVCID NIPSQYSSYN 101 NMTTFSNSIC YARKNLSSVP LYRDLEIQLS NIASSSSKTQ SSVVLNILKL 151 AQLTSVNVIH PYVLMATVIL TILMFLFILY VTVPKLPFKL AVNKFLLLLS 201 STIVLTWGIG AMWTHVGINA SYRLVPSSSM NIITVKKGKK AAVMAWFSFA 251 FLLLDSVVLW LIFLRDRKSL KDEIDNVPCA QNRYNNYSSD SSTLHSKV*

Amino Acid Sequence (or in FASTA format)

       1  MVAISMIWFF TKRMPRIFAL AFNLISIFLL IFLLIGCYNP SNQSTFLVKY
      51  KFDDNSPFYT IIEKSYEKSN TTLGLEEVII RSGYMGVCID NIPSQYSSYN
     101  NMTTFSNSIC YARKNLSSVP LYRDLEIQLS NIASSSSKTQ SSVVLNILKL
     151  AQLTSVNVIH PYVLMATVIL TILMFLFILY VTVPKLPFKL AVNKFLLLLS
     201  STIVLTWGIG AMWTHVGINA SYRLVPSSSM NIITVKKGKK AAVMAWFSFA
     251  FLLLDSVVLW LIFLRDRKSL KDEIDNVPCA QNRYNNYSSD SSTLHSKV*

external links for Fig1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Fig1p

1)	Erdman S, et al. (1998) Pheromone-regulated genes required for yeast mating differentiation. J Cell Biol 140(3):461-83
2)	Muller EM, et al. (2003) Fig1p facilitates Ca2+ influx and cell fusion during mating of Saccharomyces cerevisiae. J Biol Chem 278(40):38461-9