KIP1/YBL063W Protein Information

Standard Name	Kip1p 1
Systematic Name	Ybl063wp
Alias	Cin9p
ORF Classification	Verified
Description	Kinesin-related motor protein required for mitotic spindle assembly, chromosome segregation, and 2 micron plasmid partitioning; functionally redundant with Cin8p for chromosomal but not plasmid functions (1, 2, 3)
Name Description	KInesin related Protein 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	1,111
Molecular Weight (Da)	125,793
Isoelectric Point (pI)	6.85

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Kip1p (InterPro)
Physical Interactions	There are 15 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012DE71 \| P28742 MIPS: YBL063W NCBI: 125417 \| 313736 \| 3851 \| 536099 \| 6319408 \| NP_009490.1 GenBank/EMBL/DDBJ: DAA07057.1 \| Z11962 \| Z23261 \| Z35824

Amino Acid Sequence (or in FASTA format)
1 MARSSLPNRR TAQFEANKRR TIAHAPSPSL SNGMHTLTPP TCNNGAATSD 51 SNIHVYVRCR SRNKREIEEK SSVVISTLGP QGKEIILSNG SHQSYSSSKK 101 TYQFDQVFGA ESDQETVFNA TAKNYIKEML HGYNCTIFAY GQTGTGKTYT 151 MSGDINILGD VQSTDNLLLG EHAGIIPRVL VDLFKELSSL NKEYSVKISF 201 LELYNENLKD LLSDSEDDDP AVNDPKRQIR IFDNNNNNSS IMVKGMQEIF 251 INSAHEGLNL LMQGSLKRKV AATKCNDLSS RSHTVFTITT NIVEQDSKDH 301 GQNKNFVKIG KLNLVDLAGS ENINRSGAEN KRAQEAGLIN KSLLTLGRVI 351 NALVDHSNHI PYRESKLTRL LQDSLGGMTK TCIIATISPA KISMEETAST 401 LEYATRAKSI KNTPQVNQSL SKDTCLKDYI QEIEKLRNDL KNSRNKQGIF 451 ITQDQLDLYE SNSILIDEQN LKIHNLREQI KKFKENYLNQ LDINNLLQSE 501 KEKLIAIIQN FNVDFSNFYS EIQKIHHTNL ELMNEVIQQR DFSLENSQKQ 551 YNTNQNMQLK ISQQVLQTLN TLQGSLNNYN SKCSEVIKGV TEELTRNVNT 601 HKAKHDSTLK SLLNITTNLL MNQMNELVRS ISTSLEIFQS DSTSHYRKDL 651 NEIYQSHQQF LKNLQNDIKS CLDSIGSSIL TSINEISQNC TTNLNSMNVL 701 IENQQSGSSK LIKEQDLEIK KLKNDLINER RISNQFNQQL AEMKRYFQDH 751 VSRTRSEFHD ELNKCIDNLK DKQSKLDQDI WQKTASIFNE TDIVVNKIHS 801 DSIASLAHNA ENTLKTVSQN NESFTNDLIS LSRGMNMDIS SKLRSLPINE 851 FLNKISQTIC ETCGDDNTIA SNPVLTSIKK FQNIICSDIA LTNEKIMSLI 901 DEIQSQIETI SNENNINLIA INENFNSLCN FILTDYDENI MQISKTQDEV 951 LSEHCEKLQS LKILGMDIFT AHSIEKPLHE HTRPEASVIK ALPLLDYPKQ 1001 FQIYRDAENK SKDDTSNSRT CIPNLSTNEN FPLSQFSPKT PVPVPDQPLP 1051 KVLIPKSINS AKSNRSKTLP NTEGTGRESQ NNLKRRFTTE PILKGEETEN 1101 NDILQNKKLH Q*

Amino Acid Sequence (or in FASTA format)

       1  MARSSLPNRR TAQFEANKRR TIAHAPSPSL SNGMHTLTPP TCNNGAATSD
      51  SNIHVYVRCR SRNKREIEEK SSVVISTLGP QGKEIILSNG SHQSYSSSKK
     101  TYQFDQVFGA ESDQETVFNA TAKNYIKEML HGYNCTIFAY GQTGTGKTYT
     151  MSGDINILGD VQSTDNLLLG EHAGIIPRVL VDLFKELSSL NKEYSVKISF
     201  LELYNENLKD LLSDSEDDDP AVNDPKRQIR IFDNNNNNSS IMVKGMQEIF
     251  INSAHEGLNL LMQGSLKRKV AATKCNDLSS RSHTVFTITT NIVEQDSKDH
     301  GQNKNFVKIG KLNLVDLAGS ENINRSGAEN KRAQEAGLIN KSLLTLGRVI
     351  NALVDHSNHI PYRESKLTRL LQDSLGGMTK TCIIATISPA KISMEETAST
     401  LEYATRAKSI KNTPQVNQSL SKDTCLKDYI QEIEKLRNDL KNSRNKQGIF
     451  ITQDQLDLYE SNSILIDEQN LKIHNLREQI KKFKENYLNQ LDINNLLQSE
     501  KEKLIAIIQN FNVDFSNFYS EIQKIHHTNL ELMNEVIQQR DFSLENSQKQ
     551  YNTNQNMQLK ISQQVLQTLN TLQGSLNNYN SKCSEVIKGV TEELTRNVNT
     601  HKAKHDSTLK SLLNITTNLL MNQMNELVRS ISTSLEIFQS DSTSHYRKDL
     651  NEIYQSHQQF LKNLQNDIKS CLDSIGSSIL TSINEISQNC TTNLNSMNVL
     701  IENQQSGSSK LIKEQDLEIK KLKNDLINER RISNQFNQQL AEMKRYFQDH
     751  VSRTRSEFHD ELNKCIDNLK DKQSKLDQDI WQKTASIFNE TDIVVNKIHS
     801  DSIASLAHNA ENTLKTVSQN NESFTNDLIS LSRGMNMDIS SKLRSLPINE
     851  FLNKISQTIC ETCGDDNTIA SNPVLTSIKK FQNIICSDIA LTNEKIMSLI
     901  DEIQSQIETI SNENNINLIA INENFNSLCN FILTDYDENI MQISKTQDEV
     951  LSEHCEKLQS LKILGMDIFT AHSIEKPLHE HTRPEASVIK ALPLLDYPKQ
    1001  FQIYRDAENK SKDDTSNSRT CIPNLSTNEN FPLSQFSPKT PVPVPDQPLP
    1051  KVLIPKSINS AKSNRSKTLP NTEGTGRESQ NNLKRRFTTE PILKGEETEN
    1101  NDILQNKKLH Q*

external links for Kip1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Kip1p

1)	Roof DM, et al. (1992) Kinesin-related proteins required for assembly of the mitotic spindle. J Cell Biol 118(1):95-108
2)	Hoyt MA, et al. (1992) Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly. J Cell Biol 118(1):109-20
3)	Cui H, et al. (2009) The selfish yeast plasmid uses the nuclear motor Kip1p but not Cin8p for its localization and equal segregation. J Cell Biol 185(2):251-64