RIB1/YBL033C Protein Information

Standard Name	Rib1p 1, 2
Systematic Name	Ybl033cp
ORF Classification	Verified
Description	GTP cyclohydrolase II; catalyzes the first step of the riboflavin biosynthesis pathway (1, 3, 4)
Name Description	RIBoflavin biosynthesis 1

Experimental Data
Molecules/cell	9520 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	345
Molecular Weight (Da)	38,332
Isoelectric Point (pI)	6.3

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rib1p (InterPro)
Physical Interactions	There are 6 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000011DD23 \| P38066 MIPS: YBL033C NCBI: 3915708 \| 4388560 \| 511141 \| 6319438 \| 642219 \| NP_009520.1 GenBank/EMBL/DDBJ: DAA07086.1 \| X74738 \| Z21617 \| Z35794
External Classifications	EC: 3.5.4.25 [GTP cyclohydrolase II]

Amino Acid Sequence (or in FASTA format)
1 MTIDNYDNSK QDSSKYEVSG TGDGRNGDGG LPLVQCVARA RIPTTQGPDI 51 FLHLYSNNRD NKEHLAIVFG EDIRSRSLFR RRQCETQQDR MIRGAYIGKL 101 YPGRTVADED DRLGLALEFD DSTGELLASK ATTWDAHNDT LVRIHSECYT 151 GENAWSARCD CGEQFDRAGR LIACDHEPTS NIKGGNGHGV IVYLRQEGRG 201 IGLGEKLKAY NLQDLGADTV QANLMLKHPV DARDFSLGKA ILLDLGIGNV 251 RLLTNNPEKI KQVDHAPYLK CVERVPMVPI HWTNSSEGID SKEIEGYLRT 301 KIERMGHLLT EPLKLHTNPQ PTETSEAQNQ NRMNSALSST STLAI*

Amino Acid Sequence (or in FASTA format)

       1  MTIDNYDNSK QDSSKYEVSG TGDGRNGDGG LPLVQCVARA RIPTTQGPDI
      51  FLHLYSNNRD NKEHLAIVFG EDIRSRSLFR RRQCETQQDR MIRGAYIGKL
     101  YPGRTVADED DRLGLALEFD DSTGELLASK ATTWDAHNDT LVRIHSECYT
     151  GENAWSARCD CGEQFDRAGR LIACDHEPTS NIKGGNGHGV IVYLRQEGRG
     201  IGLGEKLKAY NLQDLGADTV QANLMLKHPV DARDFSLGKA ILLDLGIGNV
     251  RLLTNNPEKI KQVDHAPYLK CVERVPMVPI HWTNSSEGID SKEIEGYLRT
     301  KIERMGHLLT EPLKLHTNPQ PTETSEAQNQ NRMNSALSST STLAI*

external links for Rib1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Rib1p

1)	Oltmanns O and Bacher A (1972) Biosynthesis of riboflavine in Saccharomyces cerevisiae: the role of genes rib 1 and rib 7. J Bacteriol 110(3):818-22
2)	Revuelta, J.L., et al. (1992) ; Personal Communication, Mortimer Map Edition 11
3)	Buitrago MJ, et al. (1993) Mapping of the RIB1 and RIB7 genes involved in the biosynthesis of riboflavin in Saccharomyces cerevisiae. Yeast 9(10):1099-102
4)	Richter G, et al. (1997) Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis. J Bacteriol 179(6):2022-8
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41