RPL19B/YBL027W Protein Information

Standard Name	Rpl19bp
Systematic Name	Ybl027wp
ORF Classification	Verified
Description	Ribosomal 60S subunit protein L19B; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal; homologous to mammalian ribosomal protein L19, no bacterial homolog; RPL19B has a paralog, RPL19A, that arose from the whole genome duplication (1, 2, 3, 4, 5)
Name Description	Ribosomal Protein of the Large subunit
Gene Product	L19B 2 , L19e 5 , L23B 2 , YL14 2 , rpl5L 2

Experimental Data
Molecules/cell	225000 6

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	189
Molecular Weight (Da)	21,704
Isoelectric Point (pI)	11.93

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rpl19bp (InterPro)
Physical Interactions	There are 82 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001682B3 \| P0CX83 MIPS: YBL027W NCBI: 338819278 \| 410562496 \| 431846 \| 536029 \| 559805 \| 602897 \| 6319444 \| 6319559 \| NP_009526.1 \| NP_009641.1 \| NM_001178267.1 \| NM_001180057.1 GenBank/EMBL/DDBJ: DAA07093.1 \| D17338 \| U16015 \| X77291 \| Z35788

Amino Acid Sequence (or in FASTA format)
1 MANLRTQKRL AASVVGVGKR KVWLDPNETS EIAQANSRNA IRKLVKNGTI 51 VKKAVTVHSK SRTRAHAQSK REGRHSGYGK RKGTREARLP SQVVWIRRLR 101 VLRRLLAKYR DAGKIDKHLY HVLYKESKGN AFKHKRALVE HIIQAKADAQ 151 REKALNEEAE ARRLKNRAAR DRRAQRVAEK RDALLKEDA*

Amino Acid Sequence (or in FASTA format)

       1  MANLRTQKRL AASVVGVGKR KVWLDPNETS EIAQANSRNA IRKLVKNGTI
      51  VKKAVTVHSK SRTRAHAQSK REGRHSGYGK RKGTREARLP SQVVWIRRLR
     101  VLRRLLAKYR DAGKIDKHLY HVLYKESKGN AFKHKRALVE HIIQAKADAQ
     151  REKALNEEAE ARRLKNRAAR DRRAQRVAEK RDALLKEDA*

external links for Rpl19bp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	GeneMANIA
YOGY

References cited on this page View Complete Literature Guide for Rpl19bp

1)	Song JM, et al. (1996) Organization and characterization of the two yeast ribosomal protein YL19 genes. Curr Genet 30(4):273-8
2)	Planta RJ and Mager WH (1998) The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14(5):471-7
3)	Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90
4)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5)	Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol 22(6):759-67
6)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41