POP8/YBL018C Protein Information Help

Standard Name Pop8p 1
Systematic Name Ybl018cp
ORF Classification Verified
Description Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs (1, 2, 3)
Name Description Processing Of Precursor RNAs
Experimental Data
Molecules/cell 4870 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 133
Molecular Weight (Da) 15,512
Isoelectric Point (pI) 4.55

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Pop8p (InterPro)
Physical Interactions There are 22 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000131F3D | P38208
MIPS: YBL018C
NCBI: 536011 | 586405 | 6319453 | NP_009535.1
GenBank/EMBL/DDBJ: DAA07102.1 | Z35779
External Classifications EC: 3.1.26.5 [Ribonuclease P]
Amino Acid Sequence (or in FASTA format)
 
       1  MGKKTFREWQ YFKLSITSFD QDVDDAHAID QMTWRQWLNN ALKRSYGIFG
      51  EGVEYSFLHV DDKLAYIRVN HADKDTFSSS ISTYISTDEL VGSPLTVSIL
     101  QESSSLRLLE VTDDDRLWLK KVMEEEEQDC KCI*

external links for Pop8p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS YeastRC Public Image Repository
YOGY CYC2008 (complexes) Pfam domains

Complexome


DIP


GeneMANIA


YeastRC Mass Spec (Seattle)


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Pop8p
1) Chamberlain JR, et al.  (1998) Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP. Genes Dev 12(11):1678-90
2) Houser-Scott F, et al.  (2002) Interactions among the protein and RNA subunits of Saccharomyces cerevisiae nuclear RNase P. Proc Natl Acad Sci U S A 99(5):2684-9
3) Marvin MC, et al.  (2011) Accumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae. RNA 17(8):1441-50
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41