UTP20/YBL004W Protein Information

Standard Name	Utp20p 1
Systematic Name	Ybl004wp
ORF Classification	Verified
Description	Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA (2)
Name Description	U Three Protein 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	2,493
Molecular Weight (Da)	287,557
Isoelectric Point (pI)	7.03

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Utp20p (InterPro)
Physical Interactions	There are 151 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001682B7 \| P35194 MIPS: YBL004W NCBI: 14270688 \| 147744598 \| 403312 \| 4388558 \| 586397 \| NP_009551.2 GenBank/EMBL/DDBJ: DAA07118.1 \| Z26494 \| Z35765

Amino Acid Sequence (or in FASTA format)
1 MAKQRQTTKS SKRYRYSSFK ARIDDLKIEP ARNLEKRVHD YVESSHFLAS 51 FDQWKEINLS AKFTEFAAEI EHDVQTLPQI LYHDKKIFNS LVSFINFHDE 101 FSLQPLLDLL AQFCHDLGPD FLKFYEEAIK TLINLLDAAI EFESSNVFEW 151 GFNCLAYIFK YLSKFLVKKL VLTCDLLIPL LSHSKEYLSR FSAEALSFLV 201 RKCPVSNLRE FVRSVFEKLE GDDEQTNLYE GLLILFTESM TSTQETLHSK 251 AKAIMSVLLH EALTKSSPER SVSLLSDIWM NISKYASIES LLPVYEVMYQ 301 DFNDSLDATN IDRILKVLTT IVFSESGRKI PDWNKITILI ERIMSQSENC 351 ASLSQDKVAF LFALFIRNSD VKTLTLFHQK LFNYALTNIS DCFLEFFQFA 401 LRLSYERVFS FNGLKFLQLF LKKNWQSQGK KIALFFLEVD DKPELQKVRE 451 VNFPEEFILS IRDFFVTAEI NDSNDLFEIY WRAIIFKYSK LQNTEIIIPL 501 LERIFSTFAS PDNFTKDMVG TLLKIYRKED DASGNNLLKT ILDNYENYKE 551 SLNFLRGWNK LVSNLHPSES LKGLMSHYPS LLLSLTDNFM LPDGKIRYET 601 LELMKTLMIL QGMQVPDLLS SCMVIEEIPL TLQNARDLTI RIKNVGAEFG 651 KTKTDKLVSS FFLKYLFGLL TVRFSPVWTG VFDTLPNVYT KDEALVWKLV 701 LSFIKLPDEN QNLDYYQPLL EDGANKVLWD SSVVRLRDTI DTFSHIWSKY 751 STQNTSIIST TIERRGNTTY PILIRNQALK VMLSIPQVAE NHFVDIAPFV 801 YNDFKTYKDE EDMENERVIT GSWTEVDRNV FLKTLSKFKN IKNVYSATEL 851 HDHLMVLLGS RNTDVQKLAL DALLAYKNPT LNKYRDNLKN LLDDTLFKDE 901 ITTFLTENGS QSIKAEDEKV VMPYVLRIFF GRAQVPPTSG QKRSRKIAVI 951 SVLPNFKKPY INDFLSLASE RLDYNYFFGN SHQINSSKAT LKTIRRMTGF 1001 VNIVNSTLSV LRTNFPLHTN SVLQPLIYSI AMAYYVLDTE STEEVHLRKM 1051 ASNLRQQGLK CLSSVFEFVG NTFDWSTSME DIYAVVVKPR ISHFSDENLQ 1101 QPSSLLRLFL YWAHNPSLYQ FLYYDEFATA TALMDTISNQ HVKEAVIGPI 1151 IEAADSIIRN PVNDDHYVDL VTLICTSCLK ILPSLYVKLS DSNSISTFLN 1201 LLVSITEMGF IQDDHVRSRL ISSLISILKG KLKKLQENDT QKILKILKLI 1251 VFNYNCSWSD IEELYTTISS LFKTFDERNL RVSLTELFIE LGRKVPELES 1301 ISKLVADLNS YSSSRMHEYD FPRILSTFKG LIEDGYKSYS ELEWLPLLFT 1351 FLHFINNKEE LALRTNASHA IMKFIDFINE KPNLNEASKS ISMLKDILLP 1401 NIRIGLRDSL EEVQSEYVSV LSYMVKNTKY FTDFEDMAIL LYNGDEEADF 1451 FTNVNHIQLH RRQRAIKRLG EHAHQLKDNS ISHYLIPMIE HYVFSDDERY 1501 RNIGNETQIA IGGLAQHMSW NQYKALLRRY ISMLKTKPNQ MKQAVQLIVQ 1551 LSVPLRETLR IVRDGAESKL TLSKFPSNLD EPSNFIKQEL YPTLSKILGT 1601 RDDETIIERM PIAEALVNIV LGLTNDDITN FLPSILTNIC QVLRSKSEEL 1651 RDAVRVTLGK ISIILGAEYL VFVIKELMAT LKRGSQIHVL SYTVHYILKS 1701 MHGVLKHSDL DTSSSMIVKI IMENIFGFAG EEKDSENYHT KVKEIKSNKS 1751 YDAGEILASN ISLTEFGTLL SPVKALLMVR INLRNQNKLS ELLRRYLLGL 1801 NHNSDSESES ILKFCHQLFQ ESEMSNSPQI PKKKVKDQVD EKEDFFLVNL 1851 ESKSYTINSN SLLLNSTLQK FALDLLRNVI TRHRSFLTVS HLEGFIPFLR 1901 DSLLSENEGV VISTLRILIT LIRLDFSDES SEIFKNCARK VLNIIKVSPS 1951 TSSELCQMGL KFLSAFIRHT DSTLKDTALS YVLGRVLPDL NEPSRQGLAF 2001 NFLKALVSKH IMLPELYDIA DTTREIMVTN HSKEIRDVSR SVYYQFLMEY 2051 DQSKGRLEKQ FKFMVDNLQY PTESGRQSVM ELINLIITKA NPALLSKLSS 2101 SFFLALVNVS FNDDAPRCRE MASVLISTML PKLENKDLEI VEKYIAAWLK 2151 QVDNASFLNL GLRTYKVYLK SIGFEHTIEL DELAIKRIRY ILSDTSVGSE 2201 HQWDLVYSAL NTFSSYMEAT ESVYKHGFKD IWDGIITCLL YPHSWVRQSA 2251 ANLVHQLIAN KDKLEISLTN LEIQTIATRI LHQLGAPSIP ENLANVSIKT 2301 LVNISILWKE QRTPFIMDVS KQTGEDLKYT TAIDYMVTRI GGIIRSDEHR 2351 MDSFMSKKAC IQLLALLVQV LDEDEVIAEG EKILLPLYGY LETYYSRAVD 2401 EEQEELRTLS NECLKILEDK LQVSDFTKIY TAVKQTVLER RKERRSKRAI 2451 LAVNAPQISA DKKLRKHARS REKRKHEKDE NGYYQRRNKR KRA*

Amino Acid Sequence (or in FASTA format)

       1  MAKQRQTTKS SKRYRYSSFK ARIDDLKIEP ARNLEKRVHD YVESSHFLAS
      51  FDQWKEINLS AKFTEFAAEI EHDVQTLPQI LYHDKKIFNS LVSFINFHDE
     101  FSLQPLLDLL AQFCHDLGPD FLKFYEEAIK TLINLLDAAI EFESSNVFEW
     151  GFNCLAYIFK YLSKFLVKKL VLTCDLLIPL LSHSKEYLSR FSAEALSFLV
     201  RKCPVSNLRE FVRSVFEKLE GDDEQTNLYE GLLILFTESM TSTQETLHSK
     251  AKAIMSVLLH EALTKSSPER SVSLLSDIWM NISKYASIES LLPVYEVMYQ
     301  DFNDSLDATN IDRILKVLTT IVFSESGRKI PDWNKITILI ERIMSQSENC
     351  ASLSQDKVAF LFALFIRNSD VKTLTLFHQK LFNYALTNIS DCFLEFFQFA
     401  LRLSYERVFS FNGLKFLQLF LKKNWQSQGK KIALFFLEVD DKPELQKVRE
     451  VNFPEEFILS IRDFFVTAEI NDSNDLFEIY WRAIIFKYSK LQNTEIIIPL
     501  LERIFSTFAS PDNFTKDMVG TLLKIYRKED DASGNNLLKT ILDNYENYKE
     551  SLNFLRGWNK LVSNLHPSES LKGLMSHYPS LLLSLTDNFM LPDGKIRYET
     601  LELMKTLMIL QGMQVPDLLS SCMVIEEIPL TLQNARDLTI RIKNVGAEFG
     651  KTKTDKLVSS FFLKYLFGLL TVRFSPVWTG VFDTLPNVYT KDEALVWKLV
     701  LSFIKLPDEN QNLDYYQPLL EDGANKVLWD SSVVRLRDTI DTFSHIWSKY
     751  STQNTSIIST TIERRGNTTY PILIRNQALK VMLSIPQVAE NHFVDIAPFV
     801  YNDFKTYKDE EDMENERVIT GSWTEVDRNV FLKTLSKFKN IKNVYSATEL
     851  HDHLMVLLGS RNTDVQKLAL DALLAYKNPT LNKYRDNLKN LLDDTLFKDE
     901  ITTFLTENGS QSIKAEDEKV VMPYVLRIFF GRAQVPPTSG QKRSRKIAVI
     951  SVLPNFKKPY INDFLSLASE RLDYNYFFGN SHQINSSKAT LKTIRRMTGF
    1001  VNIVNSTLSV LRTNFPLHTN SVLQPLIYSI AMAYYVLDTE STEEVHLRKM
    1051  ASNLRQQGLK CLSSVFEFVG NTFDWSTSME DIYAVVVKPR ISHFSDENLQ
    1101  QPSSLLRLFL YWAHNPSLYQ FLYYDEFATA TALMDTISNQ HVKEAVIGPI
    1151  IEAADSIIRN PVNDDHYVDL VTLICTSCLK ILPSLYVKLS DSNSISTFLN
    1201  LLVSITEMGF IQDDHVRSRL ISSLISILKG KLKKLQENDT QKILKILKLI
    1251  VFNYNCSWSD IEELYTTISS LFKTFDERNL RVSLTELFIE LGRKVPELES
    1301  ISKLVADLNS YSSSRMHEYD FPRILSTFKG LIEDGYKSYS ELEWLPLLFT
    1351  FLHFINNKEE LALRTNASHA IMKFIDFINE KPNLNEASKS ISMLKDILLP
    1401  NIRIGLRDSL EEVQSEYVSV LSYMVKNTKY FTDFEDMAIL LYNGDEEADF
    1451  FTNVNHIQLH RRQRAIKRLG EHAHQLKDNS ISHYLIPMIE HYVFSDDERY
    1501  RNIGNETQIA IGGLAQHMSW NQYKALLRRY ISMLKTKPNQ MKQAVQLIVQ
    1551  LSVPLRETLR IVRDGAESKL TLSKFPSNLD EPSNFIKQEL YPTLSKILGT
    1601  RDDETIIERM PIAEALVNIV LGLTNDDITN FLPSILTNIC QVLRSKSEEL
    1651  RDAVRVTLGK ISIILGAEYL VFVIKELMAT LKRGSQIHVL SYTVHYILKS
    1701  MHGVLKHSDL DTSSSMIVKI IMENIFGFAG EEKDSENYHT KVKEIKSNKS
    1751  YDAGEILASN ISLTEFGTLL SPVKALLMVR INLRNQNKLS ELLRRYLLGL
    1801  NHNSDSESES ILKFCHQLFQ ESEMSNSPQI PKKKVKDQVD EKEDFFLVNL
    1851  ESKSYTINSN SLLLNSTLQK FALDLLRNVI TRHRSFLTVS HLEGFIPFLR
    1901  DSLLSENEGV VISTLRILIT LIRLDFSDES SEIFKNCARK VLNIIKVSPS
    1951  TSSELCQMGL KFLSAFIRHT DSTLKDTALS YVLGRVLPDL NEPSRQGLAF
    2001  NFLKALVSKH IMLPELYDIA DTTREIMVTN HSKEIRDVSR SVYYQFLMEY
    2051  DQSKGRLEKQ FKFMVDNLQY PTESGRQSVM ELINLIITKA NPALLSKLSS
    2101  SFFLALVNVS FNDDAPRCRE MASVLISTML PKLENKDLEI VEKYIAAWLK
    2151  QVDNASFLNL GLRTYKVYLK SIGFEHTIEL DELAIKRIRY ILSDTSVGSE
    2201  HQWDLVYSAL NTFSSYMEAT ESVYKHGFKD IWDGIITCLL YPHSWVRQSA
    2251  ANLVHQLIAN KDKLEISLTN LEIQTIATRI LHQLGAPSIP ENLANVSIKT
    2301  LVNISILWKE QRTPFIMDVS KQTGEDLKYT TAIDYMVTRI GGIIRSDEHR
    2351  MDSFMSKKAC IQLLALLVQV LDEDEVIAEG EKILLPLYGY LETYYSRAVD
    2401  EEQEELRTLS NECLKILEDK LQVSDFTKIY TAVKQTVLER RKERRSKRAI
    2451  LAVNAPQISA DKKLRKHARS REKRKHEKDE NGYYQRRNKR KRA*

external links for Utp20p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
YGOB	CYC2008 (complexes)	Pfam domains
YOGY	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Utp20p

1)	Samanta MP and Liang S (2003) Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci U S A 100(22):12579-83
2)	Bernstein KA, et al. (2004) The small-subunit processome is a ribosome assembly intermediate. Eukaryot Cell 3(6):1619-26