HTA2/YBL003C Protein Information Help

Standard Name Hta2p
Systematic Name Ybl003cp
Alias H2a2p 1
ORF Classification Verified
Description Histone H2A, core histone protein required for chromatin assembly and chromosome function; one of two nearly identical (see also HTA1) subtypes; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p (1, 2, 3, 4, 5)
Name Description Histone h Two A 1
Experimental Data
Molecules/cell 32100 6
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 132
Molecular Weight (Da) 13,989
Isoelectric Point (pI) 11.43

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Hta2p (InterPro)
Physical Interactions There are 374 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000036CFA | P04912
MIPS: YBL003C
NCBI: 121976 | 3753 | 403313 | 51013681 | 535978 | 6319470 | NP_009552.1
GenBank/EMBL/DDBJ: DAA07119.1 | AY693115 | V01305 | Z26494 | Z35764
Amino Acid Sequence (or in FASTA format)
 
       1  MSGGKGGKAG SAAKASQSRS AKAGLTFPVG RVHRLLRRGN YAQRIGSGAP
      51  VYLTAVLEYL AAEILELAGN AARDNKKTRI IPRHLQLAIR NDDELNKLLG
     101  NVTIAQGGVL PNIHQNLLPK KSAKTAKASQ EL*

external links for Hta2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
YGOB BioPIXIE MIPS YeastGFP
YOGY CYC2008 (complexes) Pfam domains YeastRC Public Image Repository

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA


YeastRC Mass Spec (Seattle)

References cited on this page View Complete Literature Guide for Hta2p
1) Choe J, et al.  (1982) The two yeast histone H2A genes encode similar protein subtypes. Proc Natl Acad Sci U S A 79(5):1484-7
2) Norris D, et al.  (1988) The effect of histone gene deletions on chromatin structure in Saccharomyces cerevisiae. Science 242(4879):759-61
3) Downs JA, et al.  (2000) A role for Saccharomyces cerevisiae histone H2A in DNA repair. Nature 408(6815):1001-4
4) Meeks-Wagner D and Hartwell LH  (1986) Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission. Cell 44(1):43-52
5) Song OK, et al.  (2003) An Nalpha-acetyltransferase responsible for acetylation of the N-terminal residues of histones H4 and H2A. J Biol Chem 278(40):38109-12
6) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41