FLO1/YAR050W Protein Information

Standard Name	Flo1p
Systematic Name	Yar050wp
Alias	Flo2p , Flo4p
ORF Classification	Verified
Description	Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p (1, 2)
Name Description	FLOcculation

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	1,537
Molecular Weight (Da)	160,667
Isoelectric Point (pI)	3.93

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Flo1p (InterPro)
Transmembrane Domains	There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 2 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001682A7 \| P32768 MIPS: YAR050W NCBI: 119370495 \| 1346018 \| 154816264 \| 535934 \| 61612127 \| 61612133 \| 61612139 \| 61612142 \| 6319341 \| 694125 \| NP_009424.1 GenBank/EMBL/DDBJ: DAA07007.1 \| AY949845 \| AY949846 \| AY949847 \| AY949848 \| EF670005 \| L28920 \| X78160

Amino Acid Sequence (or in FASTA format)
1 MTMPHRYMFL AVFTLLALTS VASGATEACL PAGQRKSGMN INFYQYSLKD 51 SSTYSNAAYM AYGYASKTKL GSVGGQTDIS IDYNIPCVSS SGTFPCPQED 101 SYGNWGCKGM GACSNSQGIA YWSTDLFGFY TTPTNVTLEM TGYFLPPQTG 151 SYTFKFATVD DSAILSVGGA TAFNCCAQQQ PPITSTNFTI DGIKPWGGSL 201 PPNIEGTVYM YAGYYYPMKV VYSNAVSWGT LPISVTLPDG TTVSDDFEGY 251 VYSFDDDLSQ SNCTVPDPSN YAVSTTTTTT EPWTGTFTST STEMTTVTGT 301 NGVPTDETVI VIRTPTTAST IITTTEPWNS TFTSTSTELT TVTGTNGVRT 351 DETIIVIRTP TTATTAITTT EPWNSTFTST STELTTVTGT NGLPTDETII 401 VIRTPTTATT AMTTTQPWND TFTSTSTELT TVTGTNGLPT DETIIVIRTP 451 TTATTAMTTT QPWNDTFTST STELTTVTGT NGLPTDETII VIRTPTTATT 501 AMTTTQPWND TFTSTSTEIT TVTGTNGLPT DETIIVIRTP TTATTAMTTP 551 QPWNDTFTST STEMTTVTGT NGLPTDETII VIRTPTTATT AITTTEPWNS 601 TFTSTSTEMT TVTGTNGLPT DETIIVIRTP TTATTAITTT QPWNDTFTST 651 STEMTTVTGT NGLPTDETII VIRTPTTATT AMTTTQPWND TFTSTSTEIT 701 TVTGTTGLPT DETIIVIRTP TTATTAMTTT QPWNDTFTST STEMTTVTGT 751 NGVPTDETVI VIRTPTSEGL ISTTTEPWTG TFTSTSTEMT TVTGTNGQPT 801 DETVIVIRTP TSEGLVTTTT EPWTGTFTST STEMTTITGT NGVPTDETVI 851 VIRTPTSEGL ISTTTEPWTG TFTSTSTEMT TITGTNGQPT DETVIVIRTP 901 TSEGLISTTT EPWTGTFTST STEMTHVTGT NGVPTDETVI VIRTPTSEGL 951 ISTTTEPWTG TFTSTSTEVT TITGTNGQPT DETVIVIRTP TSEGLISTTT 1001 EPWTGTFTST STEMTTVTGT NGQPTDETVI VIRTPTSEGL VTTTTEPWTG 1051 TFTSTSTEMS TVTGTNGLPT DETVIVVKTP TTAISSSLSS SSSGQITSSI 1101 TSSRPIITPF YPSNGTSVIS SSVISSSVTS SLFTSSPVIS SSVISSSTTT 1151 STSIFSESSK SSVIPTSSST SGSSESETSS AGSVSSSSFI SSESSKSPTY 1201 SSSSLPLVTS ATTSQETASS LPPATTTKTS EQTTLVTVTS CESHVCTESI 1251 SPAIVSTATV TVSGVTTEYT TWCPISTTET TKQTKGTTEQ TTETTKQTTV 1301 VTISSCESDV CSKTASPAIV STSTATINGV TTEYTTWCPI STTESRQQTT 1351 LVTVTSCESG VCSETASPAI VSTATATVND VVTVYPTWRP QTANEESVSS 1401 KMNSATGETT TNTLAAETTT NTVAAETITN TGAAETKTVV TSSLSRSNHA 1451 ETQTASATDV IGHSSSVVSV SETGNTKSLT SSGLSTMSQQ PRSTPASSMV 1501 GYSTASLEIS TYAGSANSLL AGSGLSVFIA SLLLAII*

Amino Acid Sequence (or in FASTA format)

       1  MTMPHRYMFL AVFTLLALTS VASGATEACL PAGQRKSGMN INFYQYSLKD
      51  SSTYSNAAYM AYGYASKTKL GSVGGQTDIS IDYNIPCVSS SGTFPCPQED
     101  SYGNWGCKGM GACSNSQGIA YWSTDLFGFY TTPTNVTLEM TGYFLPPQTG
     151  SYTFKFATVD DSAILSVGGA TAFNCCAQQQ PPITSTNFTI DGIKPWGGSL
     201  PPNIEGTVYM YAGYYYPMKV VYSNAVSWGT LPISVTLPDG TTVSDDFEGY
     251  VYSFDDDLSQ SNCTVPDPSN YAVSTTTTTT EPWTGTFTST STEMTTVTGT
     301  NGVPTDETVI VIRTPTTAST IITTTEPWNS TFTSTSTELT TVTGTNGVRT
     351  DETIIVIRTP TTATTAITTT EPWNSTFTST STELTTVTGT NGLPTDETII
     401  VIRTPTTATT AMTTTQPWND TFTSTSTELT TVTGTNGLPT DETIIVIRTP
     451  TTATTAMTTT QPWNDTFTST STELTTVTGT NGLPTDETII VIRTPTTATT
     501  AMTTTQPWND TFTSTSTEIT TVTGTNGLPT DETIIVIRTP TTATTAMTTP
     551  QPWNDTFTST STEMTTVTGT NGLPTDETII VIRTPTTATT AITTTEPWNS
     601  TFTSTSTEMT TVTGTNGLPT DETIIVIRTP TTATTAITTT QPWNDTFTST
     651  STEMTTVTGT NGLPTDETII VIRTPTTATT AMTTTQPWND TFTSTSTEIT
     701  TVTGTTGLPT DETIIVIRTP TTATTAMTTT QPWNDTFTST STEMTTVTGT
     751  NGVPTDETVI VIRTPTSEGL ISTTTEPWTG TFTSTSTEMT TVTGTNGQPT
     801  DETVIVIRTP TSEGLVTTTT EPWTGTFTST STEMTTITGT NGVPTDETVI
     851  VIRTPTSEGL ISTTTEPWTG TFTSTSTEMT TITGTNGQPT DETVIVIRTP
     901  TSEGLISTTT EPWTGTFTST STEMTHVTGT NGVPTDETVI VIRTPTSEGL
     951  ISTTTEPWTG TFTSTSTEVT TITGTNGQPT DETVIVIRTP TSEGLISTTT
    1001  EPWTGTFTST STEMTTVTGT NGQPTDETVI VIRTPTSEGL VTTTTEPWTG
    1051  TFTSTSTEMS TVTGTNGLPT DETVIVVKTP TTAISSSLSS SSSGQITSSI
    1101  TSSRPIITPF YPSNGTSVIS SSVISSSVTS SLFTSSPVIS SSVISSSTTT
    1151  STSIFSESSK SSVIPTSSST SGSSESETSS AGSVSSSSFI SSESSKSPTY
    1201  SSSSLPLVTS ATTSQETASS LPPATTTKTS EQTTLVTVTS CESHVCTESI
    1251  SPAIVSTATV TVSGVTTEYT TWCPISTTET TKQTKGTTEQ TTETTKQTTV
    1301  VTISSCESDV CSKTASPAIV STSTATINGV TTEYTTWCPI STTESRQQTT
    1351  LVTVTSCESG VCSETASPAI VSTATATVND VVTVYPTWRP QTANEESVSS
    1401  KMNSATGETT TNTLAAETTT NTVAAETITN TGAAETKTVV TSSLSRSNHA
    1451  ETQTASATDV IGHSSSVVSV SETGNTKSLT SSGLSTMSQQ PRSTPASSMV
    1501  GYSTASLEIS TYAGSANSLL AGSGLSVFIA SLLLAII*

external links for Flo1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Flo1p

1)	Hodgson JA, et al. (1985) Discrimination by heat and proteinase treatments between flocculent phenotypes conferred on Saccharomyces cerevisiae by the genes FLO1 and FLO5. J Gen Microbiol 131(12):3219-27
2)	Kobayashi O, et al. (1998) Region of FLO1 proteins responsible for sugar recognition. J Bacteriol 180(24):6503-10