YAR009C Protein Information Help

Systematic Name Yar009cp
Description Retrotransposon TYA Gag and TYB Pol genes; in YARCTY1-1 TYB is mutant and probably non-functional; protein product forms cytoplasmic foci upon DNA replication stress (1, 2, 3) Also known as: YARCTyB1-1
Experimental Data
Molecules/cell 2220 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,196
Molecular Weight (Da) 136,731
Isoelectric Point (pI) 9.1

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Post-translational Modifications PhosphoGRID
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Yar009cp (InterPro)
Physical Interactions There are 11 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000006AADF | O13527 | A5JYZ4
NCBI: 2564964 | 311033527 | 6319323 | NP_009406.1
GenBank/EMBL/DDBJ: DAA06991.1 | L22015
External Classifications EC: 2.7.7.49 [RNA-directed DNA polymerase]
EC: 2.7.7.7 [DNA-directed DNA polymerase]
EC: 3.1.26.4 [Ribonuclease H]
Amino Acid Sequence (or in FASTA format)
 
       1  METFTGYLKS TCFHQISPYP PSIMSIQVKV HANILILSFI ECLRMPMHRQ
      51  IRYSLKNNTI TYFNESDVDW SSAIDYQCPD CLIGKSTKHR HIKGSRLKYQ
     101  NSYEPFQYLH TDIFGPVHNL PKSAPSYFIS FTDETTKLRW VYPLHDRRED
     151  SILDVFTTIL AFIKNQFQAS VLVIQMDRGS EYTNRTLHKF LEKNGITPCY
     201  TTTADSRAHG VAERLNRTLL DDCRTQLQCS GLPNHLWFSA IEFSTIVRNS
     251  LASPKSKKSA RQHAGLAGLD ISTLLPFGQP VIVNDHNPNS KIHPRGIPGY
     301  ALHPSRNSYG YIIYLPSLKK TVDTTNYVIL QGKESRLDQF NYDALTFDED
     351  LNRLTASYHS FIASNEIQES NDLNIESDHD FQSDIELHPE QPRNVLSKAV
     401  SPTDSTPPST HTEDSKRVSK TNIRAPREVD PNISESNILP SKKRSSTPQI
     451  SNIESTGSGG MHKLNVPLLA PMSQSNTHES SHASKSKDFR HSDSYSENET
     501  NHTNVPISST GGTNNKTVPQ ISDQETEKRI IHRSPSIDAS PPENNSSHNI
     551  VPIKTPTTVS EQNTEESIIA DLPLPDLPPE SPTEFPDPFK ELPPINSHQT
     601  NSSLGGIGDS NAYTTINSKK RSLEDNETEI KVSRDTWNTK NMRSLEPPRS
     651  KKRIHLIAAV KAVKSIKPIR TTLRYDEAIT YNKDIKEKEK YIEAYHKEVN
     701  QLLKMNTWDT DKYYDRKEID PKRVINSMFI FNKKRDGTHK ARFVARGDIQ
     751  HPDTYDTGMQ SNTVHHYALM TSLSLALDNN YYITQLDISS AYLYADIKEE
     801  LYIRPPPHLG MNDKLIRLKK SLYGLKQSGA NWYETIKSYL IKQCGMEEVR
     851  GWSCVFKNSQ VTICLFVDDM ILFSKDLNAN KKIITTLKKQ YDTKIINLGE
     901  SDNEIQYDIL GLEIKYQRGK YMKLGMEKSL TEKLPKLNVP LNPKGKKLRA
     951  PGQPGLYIDQ DELEIDEDEY KEKVHEMQKL IGLASYVGYK FRFDLLYYIN
    1001  TLAQHILFPS RQVLDMTYEL IQFMWDTRDK QLIWHKNKPT EPDNKLVAIS
    1051  DASYGNQPYY KSQIGNIYLL NGKVIGGKST KASLTCTSTT EAEIHAISES
    1101  VPLLNNLSYL IQELNKKPII KGLLTDSRST ISIIKSTNEE KFRNRFFGTK
    1151  AMRLRDEVSG NNLYVYYIET KKNIADVMTK PLPIKTFKLL TNKWIH*

external links for Yar009cp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YeastGFP
DIP Pfam domains YeastRC Public Image Repository

References cited on this page View Complete Literature Guide for Yar009cp
1) Kim JM, et al.  (1998) Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence. Genome Res 8(5):464-78
2) Lesage P and Todeschini AL  (2005) Happy together: the life and times of Ty retrotransposons and their hosts. Cytogenet Genome Res 110(1-4):70-90
3) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41