SEO1/YAL067C Protein Information

Standard Name	Seo1p
Systematic Name	Yal067cp
ORF Classification	Verified
Description	Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide (1, 2)
Name Description	Suppressor of sulfoxyde EthiOnine resistance 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	593
Molecular Weight (Da)	68,842
Isoelectric Point (pI)	8.05

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Seo1p (InterPro)
Transmembrane Domains	There are 12 total predicted transmembrane domains (TMHMM)
Physical Interactions	There are 4 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000135857 \| P39709 MIPS: YAL067C NCBI: 595520 \| 6319250 \| 731298 \| NP_009333.1 GenBank/EMBL/DDBJ: DAA06920.1 \| U12980
External Classifications	TC: 2.A.1.14 [The Anion: Cation Symporter (ACS) Family]

Amino Acid Sequence (or in FASTA format)
1 MYSIVKEIIV DPYKRLKWGF IPVKRQVEDL PDDLNSTEIV TISNSIQSHE 51 TAENFITTTS EKDQLHFETS SYSEHKDNVN VTRSYEYRDE ADRPWWRFFD 101 EQEYRINEKE RSHNKWYSWF KQGTSFKEKK LLIKLDVLLA FYSCIAYWVK 151 YLDTVNINNA YVSGMKEDLG FQGNDLVHTQ VMYTVGNIIF QLPFLIYLNK 201 LPLNYVLPSL DLCWSLLTVG AAYVNSVPHL KAIRFFIGAF EAPSYLAYQY 251 LFGSFYKHDE MVRRSAFYYL GQYIGILSAG GIQSAVYSSL NGVNGLEGWR 301 WNFIIDAIVS VVVGLIGFYS LPGDPYNCYS IFLTDDEIRL ARKRLKENQT 351 GKSDFETKVF DIKLWKTIFS DWKIYILTLW NIFCWNDSNV SSGAYLLWLK 401 SLKRYSIPKL NQLSMITPGL GMVYLMLTGI IADKLHSRWF AIIFTQVFNI 451 IGNSILAAWD VAEGAKWFAF MLQCFGWAMA PVLYSWQNDI CRRDAQTRAI 501 TLVTMNIMAQ SSTAWISVLV WKTEEAPRYL KGFTFTACSA FCLSIWTFVV 551 LYFYKRDERN NAKKNGIVLY NSKHGVEKPT SKDVETLSVS DEK*

Amino Acid Sequence (or in FASTA format)

       1  MYSIVKEIIV DPYKRLKWGF IPVKRQVEDL PDDLNSTEIV TISNSIQSHE
      51  TAENFITTTS EKDQLHFETS SYSEHKDNVN VTRSYEYRDE ADRPWWRFFD
     101  EQEYRINEKE RSHNKWYSWF KQGTSFKEKK LLIKLDVLLA FYSCIAYWVK
     151  YLDTVNINNA YVSGMKEDLG FQGNDLVHTQ VMYTVGNIIF QLPFLIYLNK
     201  LPLNYVLPSL DLCWSLLTVG AAYVNSVPHL KAIRFFIGAF EAPSYLAYQY
     251  LFGSFYKHDE MVRRSAFYYL GQYIGILSAG GIQSAVYSSL NGVNGLEGWR
     301  WNFIIDAIVS VVVGLIGFYS LPGDPYNCYS IFLTDDEIRL ARKRLKENQT
     351  GKSDFETKVF DIKLWKTIFS DWKIYILTLW NIFCWNDSNV SSGAYLLWLK
     401  SLKRYSIPKL NQLSMITPGL GMVYLMLTGI IADKLHSRWF AIIFTQVFNI
     451  IGNSILAAWD VAEGAKWFAF MLQCFGWAMA PVLYSWQNDI CRRDAQTRAI
     501  TLVTMNIMAQ SSTAWISVLV WKTEEAPRYL KGFTFTACSA FCLSIWTFVV
     551  LYFYKRDERN NAKKNGIVLY NSKHGVEKPT SKDVETLSVS DEK*

external links for Seo1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS
Candida (CGD)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	TCDB
YOGY	DIP	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Seo1p

1)	Isnard AD, et al. (1996) The study of methionine uptake in Saccharomyces cerevisiae reveals a new family of amino acid permeases. J Mol Biol 262(4):473-84
2)	Nelissen B, et al. (1997) Classification of all putative permeases and other membrane plurispanners of the major facilitator superfamily encoded by the complete genome of Saccharomyces cerevisiae. FEMS Microbiol Rev 21(2):113-34