BDH2/YAL061W Protein Information

Standard Name	Bdh2p 1
Systematic Name	Yal061wp
ORF Classification	Uncharacterized
Description	Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3 (1, 2, 3, 4)

Experimental Data
Molecules/cell	3090 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	417
Molecular Weight (Da)	46,098
Isoelectric Point (pI)	6.04

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Bdh2p (InterPro)
Physical Interactions	There are 4 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000052EC0 \| P39713 MIPS: YAL061W NCBI: 51012911 \| 595525 \| 6319257 \| 731294 \| NP_009340.1 GenBank/EMBL/DDBJ: DAA06928.1 \| AY692730 \| U12980

Amino Acid Sequence (or in FASTA format)
1 MRALAYFGKG NIRFTNHLKE PHIVAPDELV IDIEWCGICG TDLHEYTDGP 51 IFFPEDGHTH EISHNPLPQA MGHEMAGTVL EVGPGVKNLK VGDKVVVEPT 101 GTCRDRYRWP LSPNVDKEWC AACKKGYYNI CSYLGLCGAG VQSGGFAERV 151 VMNESHCYKV PDFVPLDVAA LIQPLAVCWH AIRVCEFKAG STALIIGAGP 201 IGLGTILALN AAGCKDIVVS EPAKVRRELA EKMGARVYDP TAHAAKESID 251 YLRSIADGGD GFDYTFDCSG LEVTLNAAIQ CLTFRGTAVN LAMWGHHKIQ 301 FSPMDITLHE RKYTGSMCYT HHDFEAVIEA LEEGRIDIDR ARHMITGRVN 351 IEDGLDGAIM KLINEKESTI KIILTPNNHG ELNREADNEK KEISELSSRK 401 DQERLRESIN EAKLRHT*

Amino Acid Sequence (or in FASTA format)

       1  MRALAYFGKG NIRFTNHLKE PHIVAPDELV IDIEWCGICG TDLHEYTDGP
      51  IFFPEDGHTH EISHNPLPQA MGHEMAGTVL EVGPGVKNLK VGDKVVVEPT
     101  GTCRDRYRWP LSPNVDKEWC AACKKGYYNI CSYLGLCGAG VQSGGFAERV
     151  VMNESHCYKV PDFVPLDVAA LIQPLAVCWH AIRVCEFKAG STALIIGAGP
     201  IGLGTILALN AAGCKDIVVS EPAKVRRELA EKMGARVYDP TAHAAKESID
     251  YLRSIADGGD GFDYTFDCSG LEVTLNAAIQ CLTFRGTAVN LAMWGHHKIQ
     301  FSPMDITLHE RKYTGSMCYT HHDFEAVIEA LEEGRIDIDR ARHMITGRVN
     351  IEDGLDGAIM KLINEKESTI KIILTPNNHG ELNREADNEK KEISELSSRK
     401  DQERLRESIN EAKLRHT*

external links for Bdh2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Bdh2p

1)	Dickinson JR, et al. (2003) The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae. J Biol Chem 278(10):8028-34
2)	Gonzalez E, et al. (2000) Characterization of a (2R,3R)-2,3-butanediol dehydrogenase as the Saccharomyces cerevisiae YAL060W gene product. Disruption and induction of the gene. J Biol Chem 275(46):35876-85
3)	do Valle Matta MA, et al. (2001) Novel target genes of the yeast regulator Pdr1p: a contribution of the TPO1 gene in resistance to quinidine and other drugs. Gene 272(1-2):111-9
4)	Devaux F, et al. (2002) Genome-wide studies on the nuclear PDR3-controlled response to mitochondrial dysfunction in yeast. FEBS Lett 515(1-3):25-8
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41