BDH1/YAL060W Protein Information

Standard Name	Bdh1p
Systematic Name	Yal060wp
ORF Classification	Verified
Description	NAD-dependent (R,R)-butanediol dehydrogenase, catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source (1) Also known as: BDH 1
Name Description	Butanediol DeHydrogenase 1
Gene Product	(2R,3R)-2,3-butanediol dehydrogenase 1

Experimental Data
Molecules/cell	8730 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	382
Molecular Weight (Da)	41,582
Isoelectric Point (pI)	6.55

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Bdh1p (InterPro)
Physical Interactions	There are 8 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000403EE0 \| P39714 MIPS: YAL060W NCBI: 330443362 \| 341940281 \| 51013295 \| 595526 \| 731293 \| NP_009341.2 \| NM_001178202.2 GenBank/EMBL/DDBJ: DAA06929.2 \| AY692922 \| U12980
External Classifications	EC: 1.1.1.303 [Diacetyl reductase ((R)-acetoin forming)] EC: 1.1.1.4 [(R,R)-butanediol dehydrogenase]

Amino Acid Sequence (or in FASTA format)
1 MRALAYFKKG DIHFTNDIPR PEIQTDDEVI IDVSWCGICG SDLHEYLDGP 51 IFMPKDGECH KLSNAALPLA MGHEMSGIVS KVGPKVTKVK VGDHVVVDAA 101 SSCADLHCWP HSKFYNSKPC DACQRGSENL CTHAGFVGLG VISGGFAEQV 151 VVSQHHIIPV PKEIPLDVAA LVEPLSVTWH AVKISGFKKG SSALVLGAGP 201 IGLCTILVLK GMGASKIVVS EIAERRIEMA KKLGVEVFNP SKHGHKSIEI 251 LRGLTKSHDG FDYSYDCSGI QVTFETSLKA LTFKGTATNI AVWGPKPVPF 301 QPMDVTLQEK VMTGSIGYVV EDFEEVVRAI HNGDIAMEDC KQLITGKQRI 351 EDGWEKGFQE LMDHKESNVK ILLTPNNHGE MK*

Amino Acid Sequence (or in FASTA format)

       1  MRALAYFKKG DIHFTNDIPR PEIQTDDEVI IDVSWCGICG SDLHEYLDGP
      51  IFMPKDGECH KLSNAALPLA MGHEMSGIVS KVGPKVTKVK VGDHVVVDAA
     101  SSCADLHCWP HSKFYNSKPC DACQRGSENL CTHAGFVGLG VISGGFAEQV
     151  VVSQHHIIPV PKEIPLDVAA LVEPLSVTWH AVKISGFKKG SSALVLGAGP
     201  IGLCTILVLK GMGASKIVVS EIAERRIEMA KKLGVEVFNP SKHGHKSIEI
     251  LRGLTKSHDG FDYSYDCSGI QVTFETSLKA LTFKGTATNI AVWGPKPVPF
     301  QPMDVTLQEK VMTGSIGYVV EDFEEVVRAI HNGDIAMEDC KQLITGKQRI
     351  EDGWEKGFQE LMDHKESNVK ILLTPNNHGE MK*

external links for Bdh1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Bdh1p

1)	Gonzalez E, et al. (2000) Characterization of a (2R,3R)-2,3-butanediol dehydrogenase as the Saccharomyces cerevisiae YAL060W gene product. Disruption and induction of the gene. J Biol Chem 275(46):35876-85
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41