ECM1/YAL059W Protein Information

Standard Name	Ecm1p 1
Systematic Name	Yal059wp
ORF Classification	Verified
Description	Pre-ribosomal factor involved in 60S ribosomal protein subunit export; associates with the pre-60S particle; shuttles between the nucleus and cytoplasm (2, 3)
Name Description	ExtraCellular Mutant

Experimental Data
Molecules/cell	2840 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	212
Molecular Weight (Da)	23,891
Isoelectric Point (pI)	10.44

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ecm1p (InterPro)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 27 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000254505 \| P39715 MIPS: YAL059W NCBI: 330443364 \| 341940486 \| 45270226 \| 595527 \| 731292 \| NP_009342.2 GenBank/EMBL/DDBJ: DAA06930.2 \| AY558168 \| U12980

Amino Acid Sequence (or in FASTA format)
1 MWEQRRQKVV FSLTILVRYR LKQSMAKKIS KNSRAARQSD ALEPEVKDLS 51 ELPRAEKTDL TNILIRTAAK NEALLEAKIS KKANKSKRGK KLNKKALEDK 101 LANSISSMDR DRLVKALNFT NRLDGKIAKS ISRAKYIQNT RKAGWDSTNE 151 TIKKELAFLN GGLSVQAKSA SEGNAEKEDE EIPEVFDSLA EDNTVQKTPT 201 NRFGVLPDDV EE*

Amino Acid Sequence (or in FASTA format)

       1  MWEQRRQKVV FSLTILVRYR LKQSMAKKIS KNSRAARQSD ALEPEVKDLS
      51  ELPRAEKTDL TNILIRTAAK NEALLEAKIS KKANKSKRGK KLNKKALEDK
     101  LANSISSMDR DRLVKALNFT NRLDGKIAKS ISRAKYIQNT RKAGWDSTNE
     151  TIKKELAFLN GGLSVQAKSA SEGNAEKEDE EIPEVFDSLA EDNTVQKTPT
     201  NRFGVLPDDV EE*

external links for Ecm1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ecm1p

1)	Lussier M, et al. (1997) Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics 147(2):435-50
2)	Bassler J, et al. (2001) Identification of a 60S preribosomal particle that is closely linked to nuclear export. Mol Cell 8(3):517-29
3)	Yao Y, et al. (2010) Ecm1 is a new pre-ribosomal factor involved in pre-60S particle export. RNA 16(5):1007-17
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41