PDB Homolog: MKK1/YOR231W Help



This page presents information for the proteins of known structure with sequence similarity to the Saccharomyces cerevisiae protein MKK1/YOR231W. The analysis was performed by comparing yeast protein sequences against protein sequences in The RCSB Protein Databank (PDB) using WU-BLAST.
 
Last updated on 2016-09-15

643 PDB homolog(s) found for yeast gene MKK1/YOR231W

MKK1/YOR231W links
  • Locus Info
  • PDB protein structure(s) homologous to MKK1Homolog Source (per PDB)Protein Alignment: MKK1 vs. HomologExternal Links
    P-Value%Identical%SimilarAlignment
    3SLS ( Chain: B, A)
    Crystal Structure Of Human Mek-1 Kinase In Complex With Ucb1353770 And Amppnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.0e-534419View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.0e-534419View alignment
    3ORN ( Chain: A)
    Mitogen-Activated Protein Kinase Kinase 1 (Mek1) In Complex With Ch4987655 And Mgamp-Pnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.8e-524319View alignmentSCOP
    MMDB
    CATH
    3OS3 ( Chain: A)
    Mitogen-Activated Protein Kinase Kinase 1 (Mek1) In Complex With Ch4858061 And Mgatp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.8e-524319View alignmentSCOP
    MMDB
    CATH
    3WIG ( Chain: A)
    Human Mek1 Kinase In Complex With Ch5126766 And Mgamp-pnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.8e-524319View alignmentSCOP
    MMDB
    CATH
    4AN3 ( Chain: A)
    Crystal Structures Of Human Mek1 With Carboxamide-based Allosteric Inhibitor Xl518 (gdc-0973), Or Related Analogs.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.5e-514418View alignmentSCOP
    MMDB
    CATH
    4AN9 ( Chain: A)
    Crystal Structures Of Human Mek1 With Carboxamide-based Allosteric Inhibitor Xl518 (gdc-0973), Or Related Analogs.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.5e-514418View alignmentSCOP
    MMDB
    CATH
    4ANB ( Chain: A)
    Crystal Structures Of Human Mek1 With Carboxamide-based Allosteric Inhibitor Xl518 (gdc-0973), Or Related Analogs.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.5e-514418View alignmentSCOP
    MMDB
    CATH
    4AN2 ( Chain: A)
    Crystal Structures Of Human Mek1 With Carboxamide-based Allosteric Inhibitor Xl518 (gdc-0973), Or Related Analogs.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.5e-514418View alignmentSCOP
    MMDB
    CATH
    3W8Q ( Chain: A)
    Structure Of The Human Mitogen-activated Protein Kinase Kinase 1 (mek1)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.1e-484116View alignmentSCOP
    MMDB
    CATH
    2Y4I ( Chain: C)
    Ksr2-Mek1 Heterodimer
  • PDB_Info
  • PDB_Structure
  • Oryctolagus cuniculus5.3e-484116View alignmentSCOP
    MMDB
    CATH
    3EQD ( Chain: A)
    X-Ray Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek1) In A Binary Complex With Atp-Gs And Mg2p
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-484017View alignmentSCOP
    MMDB
    CATH
    3EQF ( Chain: A)
    X-Ray Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek1) In A Binary Complex With K252a And Mg2p
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-484017View alignmentSCOP
    MMDB
    CATH
    3EQC ( Chain: A)
    X-Ray Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek1) In A Ternary Complex With Compound 1, Atp-Gs And Mg2p
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-484017View alignmentSCOP
    MMDB
    CATH
    5EYM ( Chain: B, A)
    Mek1 In Complex With Bi 847325
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 6.8e-484017View alignmentSCOP
    MMDB
    CATH
    Chain A = 6.8e-484017View alignment
    3EQG ( Chain: A)
    X-ray Structure Of The Human Mitogen-activated Protein Kinase Kinase 1 (mek1) In A Ternary Complex With Pd, Adp And Mg2p
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-484017View alignmentSCOP
    MMDB
    CATH
    3EQH ( Chain: A)
    X-Ray Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek1) In A Ternary Complex With U0126, Adp And Mg2p
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-484017View alignmentSCOP
    MMDB
    CATH
    3EQI ( Chain: A)
    X-Ray Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek1) In A Binary Complex With Adp And Mg2p
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-484017View alignmentSCOP
    MMDB
    CATH
    4U7Z ( Chain: A)
    Mitogen-activated Protein Kinase Kinase (mek1) Bound To G805
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    4U80 ( Chain: A)
    Mek 1 Kinase Bound To G799
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    4U81 ( Chain: A)
    Mek1 Kinase Bound To Small Molecule Inhibitor G659
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    1S9J ( Chain: A)
    X-Ray Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek1) In A Complex With Ligand And Mgatp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    3DY7 ( Chain: A)
    X-Ray Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek1) In A Complex With Ligand And Mgatp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    3E8N ( Chain: A)
    X-Ray Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek1) Complexed With A Potent Inhibitor Rdea119 And Mgatp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    3V01 ( Chain: A)
    Discovery Of Novel Allosteric Mek Inhibitors Possessing Classical And Non-Classical Bidentate Ser212 Interactions.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    3V04 ( Chain: A)
    Discovery Of Novel Allosteric Mek Inhibitors Possessing Classical And Non-Classical Bidentate Ser212 Interactions.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    4ARK ( Chain: A)
    Crystal Structure Of The Catalytic Domain Of Human Map Kinase Kinase 1 (mek1) In Complex With A Small Molecule Inhibitor And Adp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    4LMN ( Chain: A)
    Crystal Structure Of Mek1 Kinase Bound To Gdc0973
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    3VVH ( Chain: A, B, C)
    X-ray Structure Of The Human Mitogen-activated Protein Kinase Kinase 1 (mek1) In Complex With An Inhibitor And Mgatp
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.4e-474017View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.4e-474017View alignment
    Chain C = 1.4e-474017View alignment
    4MNE ( Chain: A, D, E, H)
    Crystal Structure Of The Braf:mek1 Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.4e-474017View alignmentSCOP
    MMDB
    CATH
    Chain D = 1.4e-474017View alignment
    Chain E = 1.4e-474017View alignment
    Chain H = 1.4e-474017View alignment
    3EQB ( Chain: A)
    X-Ray Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek1) In A Complex With Ligand And Mgatp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    2P55 ( Chain: A)
    X-Ray Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek1) In A Complex With Ligand And Mgatp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    3PP1 ( Chain: A)
    Crystal Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek 1) In Complex With Ligand And Mgatp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    3MBL ( Chain: A)
    Crystal Structure Of The Human Mitogen-Activated Protein Kinase Kinase 1 (Mek 1) In Complex With Ligand And Mgadp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    3DV3 ( Chain: A)
    Mek1 With Pf-04622664 Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474017View alignmentSCOP
    MMDB
    CATH
    5BX0 ( Chain: A)
    An Automated Microscale Thermophoresis Screening Approach For Fragment-based Lead Discovery
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474016View alignmentSCOP
    MMDB
    CATH
    3ZM4 ( Chain: A)
    Crystal Structure Of Mek1 In Complex With Fragment 1
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474016View alignmentSCOP
    MMDB
    CATH
    3ZLS ( Chain: A)
    Crystal Structure Of Mek1 In Complex With Fragment 6
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474016View alignmentSCOP
    MMDB
    CATH
    3ZLX ( Chain: A)
    Crystal Structure Of Mek1 In Complex With Fragment 18
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474016View alignmentSCOP
    MMDB
    CATH
    3ZLY ( Chain: A)
    Crystal Structure Of Mek1 In Complex With Fragment 8
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-474016View alignmentSCOP
    MMDB
    CATH
    3ZLW ( Chain: A)
    Crystal Structure Of Mek1 In Complex With Fragment 3
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.9e-474016View alignmentSCOP
    MMDB
    CATH
    1S9I ( Chain: A, B)
    X-Ray Structure Of The Human Mitogen-Activated Protein Kinase Kinase 2 (Mek2)in A Complex With Ligand And Mgatp
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 9.9e-473818View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.9e-473818View alignment
    3VN9 ( Chain: A)
    Rifined Crystal Structure Of Non-Phosphorylated Map2k6 In A Putative Auto-Inhibition State
  • PDB_Info
  • PDB_Structure
  • Homo sapiens8.2e-453720View alignmentSCOP
    MMDB
    CATH
    3ALN ( Chain: A, B, C)
    Crystal Structure Of Human Non-Phosphorylated Mkk4 Kinase Domain Complexed With Amp-Pnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 9.4e-443819View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.4e-443819View alignment
    Chain C = 9.4e-443819View alignment
    3VUT ( Chain: B, A)
    Crystal Structures Of Non-Phosphorylated Map2k4
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 9.4e-443819View alignmentSCOP
    MMDB
    CATH
    Chain A = 9.4e-443819View alignment
    3ALO ( Chain: A)
    Crystal Structure Of Human Non-Phosphorylated Mkk4 Kinase Domain Ternary Complex With Amp-Pnp And P38 Peptide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.4e-443819View alignmentSCOP
    MMDB
    CATH
    5B2L ( Chain: A)
    A Crucial Role Of Cys218 In The Stabilization Of An Unprecedented Auto-inhibition Form Of Map2k7
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-424019View alignmentSCOP
    MMDB
    CATH
    3FME ( Chain: A)
    Crystal Structure Of Human Mitogen-Activated Protein Kinase Kinase 6 (Mek6) Activated Mutant (S207d, T211d)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.5e-423820View alignmentSCOP
    MMDB
    CATH
    5B2M ( Chain: A)
    A Crucial Role Of Cys218 In The Stabilization Of An Unprecedented Auto-inhibition Form Of Map2k7
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.5e-423920View alignmentSCOP
    MMDB
    CATH
    5B2K ( Chain: A)
    A Crucial Role Of Cys218 In The Stabilization Of An Unprecedented Auto-inhibition Form Of Map2k7
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.5e-423920View alignmentSCOP
    MMDB
    CATH
    3WZU ( Chain: A)
    The Structure Of Map2k7 In Complex With 5z-7-oxozeaenol
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.5e-423920View alignmentSCOP
    MMDB
    CATH
    2DYL ( Chain: A)
    Crystal Structure Of Human Mitogen-Activated Protein Kinase Kinase 7 Activated Mutant (S287d, T291d)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.6e-413819View alignmentSCOP
    MMDB
    CATH
    3COM ( Chain: A, B)
    Crystal Structure Of Mst1 Kinase
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 6.1e-403520View alignmentSCOP
    MMDB
    CATH
    Chain B = 6.1e-403520View alignment
    3ENM ( Chain: D, C, A, B)
    The Structure Of The Map2k Mek6 Reveals An Autoinhibitory Dimer
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain D = 7.8e-403719View alignmentSCOP
    MMDB
    CATH
    Chain C = 7.8e-403719View alignment
    Chain A = 7.8e-403719View alignment
    Chain B = 7.8e-403719View alignment
    4LGD ( Chain: A, B, C, D)
    Structural Basis For Autoactivation Of Human Mst2 Kinase And Its Regulation By Rassf5
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 7.8e-403719View alignmentSCOP
    MMDB
    CATH
    Chain B = 7.8e-403719View alignment
    Chain C = 7.8e-403719View alignment
    Chain D = 7.8e-403719View alignment
    4LG4 ( Chain: A, B, C, D, E, F)
    Structural Basis For Autoactivation Of Human Mst2 Kinase And Its Regulation By Rassf5
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 7.8e-403719View alignmentSCOP
    MMDB
    CATH
    Chain B = 7.8e-403719View alignment
    Chain C = 7.8e-403719View alignment
    Chain D = 7.8e-403719View alignment
    Chain E = 7.8e-403719View alignment
    Chain F = 7.8e-403719View alignment
    3GGF ( Chain: B, A)
    Crystal Structure Of Human SerineTHREONINE-Protein Kinase Mst4 In Complex With An Quinazolin
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 3.4e-393620View alignmentSCOP
    MMDB
    CATH
    Chain A = 3.4e-393620View alignment
    3CKW ( Chain: A)
    Crystal Structure Of Sterile 20-Like Kinase 3 (Mst3, Stk24)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-383620View alignmentSCOP
    MMDB
    CATH
    4FZA ( Chain: B)
    Crystal Structure Of Mst4-mo25 Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.3e-383620View alignmentSCOP
    MMDB
    CATH
    4FZF ( Chain: B)
    Crystal Structure Of Mst4-mo25 Complex With Dki
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.3e-383620View alignmentSCOP
    MMDB
    CATH
    4FZD ( Chain: B)
    Crystal Structure Of Mst4-mo25 Complex With Wsf Motif
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.3e-383620View alignmentSCOP
    MMDB
    CATH
    3ZHP ( Chain: C, D)
    Human Mst3 (stk24) In Complex With Mo25beta
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain C = 4.8e-383620View alignmentSCOP
    MMDB
    CATH
    Chain D = 4.8e-383620View alignment
    4QO9 ( Chain: B, A)
    Mst3 In Complex With Danusertib
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 4.8e-383520View alignmentSCOP
    MMDB
    CATH
    Chain A = 4.8e-383520View alignment
    4U8Z ( Chain: A)
    Crystal Structure Of Mst3 With A Pyrrolopyrimidine Inhibitor (pf- 06447475)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4W8D ( Chain: A)
    Crystal Structure Of Mst3 With A Pyrrolopyrimidine Inhibitor (pf- 06454589).
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4W8E ( Chain: A)
    Structure Of Mst3 With A Pyrrolopyrimidine Inhibitor (pf-06645342)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    3A7F ( Chain: A)
    Human Mst3 Kinase
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    3A7G ( Chain: A, B)
    Human Mst3 Kinase
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.8e-383520View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.8e-383520View alignment
    3A7H ( Chain: A, B)
    Human Mst3 Kinase In Complex With Atp
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.8e-383520View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.8e-383520View alignment
    3A7I ( Chain: A)
    Human Mst3 Kinase In Complex With Adenine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    3A7J ( Chain: A)
    Human Mst3 Kinase In Complex With Mnadp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    3CKX ( Chain: A)
    Crystal Structure Of Sterile 20-Like Kinase 3 (Mst3, Stk24) In Complex With Staurosporine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QML ( Chain: A)
    Mst3 In Complex With Amp-pnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMM ( Chain: A)
    Mst3 In Complex With At-9283, 4-[(2-{4-[(cyclopropylcarbamoyl)amino]- 1h-pyrazol-3-yl}-1h-benzimidazol-6-yl)methyl]morpholin-4-ium
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMN ( Chain: A)
    Mst3 In Complex With Bosutinib
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMO ( Chain: A)
    Mst3 In Complex With Imidazolo-oxindole Pkr Inhibitor C16
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMP ( Chain: A)
    Mst3 In Complex With Cdk1/2 Inhibitor Iii, 5-amino-3-{[4- (aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4- Triazole-1-carbothioamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMQ ( Chain: A)
    Mst3 In Complex With Cp-673451
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMS ( Chain: A)
    Mst3 In Complex With Dasatinib
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMT ( Chain: A)
    Mst3 In Complex With Hesperadin
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMU ( Chain: A)
    Mst3 In Complex With Jnj-7706621, 4-({5-amino-1-[(2,6-difluorophenyl) Carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMV ( Chain: A)
    Mst3 In Complex With Pf-03814735, N-{2-[(1s,4r)-6-{[4- (cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1,2,3,4- Tetrahydro-1,4-epiminonaphthalen-9-yl]-2-oxoethyl}acetamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMW ( Chain: A)
    Mst3 In Complex With Pp-121, 1-cyclopentyl-3-(1h-pyrrolo[2,3- B]pyridin-5-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMX ( Chain: A)
    Mst3 In Complex With Saracatinib
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMY ( Chain: A)
    Mst3 In Complex With Staurosporine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QMZ ( Chain: A)
    Mst3 In Complex With Sunitinib
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4QNA ( Chain: A)
    Mst3 In Complex With 2-(4,6-diamino-1,3,5-triazin-2-yl)phenol
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-383520View alignmentSCOP
    MMDB
    CATH
    4O27 ( Chain: B)
    Crystal Structure Of Mst3-mo25 Complex With Wif Motif
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.2e-383520View alignmentSCOP
    MMDB
    CATH
    2XIK ( Chain: A)
    Structure Of Human Ysk1 (Yeast Sps1-Ste20-Related Kinase 1)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens7.9e-383521View alignmentSCOP
    MMDB
    CATH
    4NZW ( Chain: B)
    Crystal Structure Of Stk25-mo25 Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-373521View alignmentSCOP
    MMDB
    CATH
    2X7F ( Chain: E, C, D, A, B)
    Crystal Structure Of The Kinase Domain Of Human Traf2- And Nck-Interacting Kinase With Wee1chk1 Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain E = 2.7e-373519View alignmentSCOP
    MMDB
    CATH
    Chain C = 2.7e-373519View alignment
    Chain D = 2.7e-373519View alignment
    Chain A = 2.7e-373519View alignment
    Chain B = 2.7e-373519View alignment
    5AX9 ( Chain: A, B, C)
    Crystal Structure Of The Kinase Domain Of Human Traf2 And Nck- Interacting Protein Kinase In Complex With Compund 9
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 5.7e-373618View alignmentSCOP
    MMDB
    CATH
    Chain B = 5.7e-373618View alignment
    Chain C = 5.7e-373618View alignment
    5CWZ ( Chain: A, C, B)
    Crystal Structure Of The Kinase Domain Of Human Traf2 And Nck- Interacting Protein Kinase
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 5.7e-373618View alignmentSCOP
    MMDB
    CATH
    Chain C = 5.7e-373618View alignment
    Chain B = 5.7e-373618View alignment
    5D7A ( Chain: C, A, B)
    Crystal Scructure Of Traf2 And Nck-interacting Protein Kinase With Ncb-0846
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain C = 5.7e-373618View alignmentSCOP
    MMDB
    CATH
    Chain A = 5.7e-373618View alignment
    Chain B = 5.7e-373618View alignment
    5DI1 ( Chain: A, B)
    Map4k4 In Complex With An Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-343618View alignment
    4U41 ( Chain: B, A)
    Map4k4 Bound To Inhibitor Compound 1
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.1e-343618View alignment
    4RVT ( Chain: A, B)
    Map4k4 In Complex With A Pyridin-2(1h)-one Derivative
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-343618View alignment
    4OBO ( Chain: A, B)
    Map4k4 In Complex With Inhibitor (compound 22), 6-(3-chlorophenyl) Quinazolin-4-amine
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-343618View alignment
    4OBP ( Chain: A, B)
    Map4k4 In Complex With Inhibitor (compound 29), 6-(2-fluoropyridin-4- Yl)pyrido[3,2-d]pyrimidin-4-amine
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-343618View alignment
    4OBQ ( Chain: A, B)
    Map4k4 In Complex With Inhibitor (compound 31), N-[3-(4- Aminoquinazolin-6-yl)-5-fluorophenyl]-2-(pyrrolidin-1-yl)acetamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-343618View alignment
    4U43 ( Chain: A, B)
    Map4k4 In Complex With Inhibitor (compound 6)
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-343618View alignment
    4U44 ( Chain: A, B)
    Map4k4 In Complex With Inhibitor (compound 16)
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-343618View alignment
    4U45 ( Chain: A, B)
    Map4k4 In Complex With Inhibitor (compound 25)
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-343618View alignment
    4ZK5 ( Chain: A, B)
    Map4k4 In Complex With Inhibitor Gne-495
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-343618View alignment
    4U3Y ( Chain: A, B)
    Apo Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (map4k4)
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-343618View alignment
    4U40 ( Chain: A, B)
    Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (map4k4) Bound To Amppnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-343618View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-343618View alignment
    4U3Z ( Chain: B, A)
    Apo Map4k4 T181e Phosphomimetic Mutant
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.5e-343617View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.5e-343617View alignment
    4U42 ( Chain: B, A)
    Map4k4 T181e Mutant Bound To Inhibitor Compound 1
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.5e-343617View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.5e-343617View alignment
    4BC6 ( Chain: A)
    Crystal Structure Of Human Serine Threonine Kinase-10 Bound To Novel Bosutinib Isoform 1, Previously Thought To Be Bosutinib
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.6e-333321View alignmentSCOP
    MMDB
    CATH
    5AJQ ( Chain: A, B)
    Human Lok (stk10) In Complex With Bosutinib
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.6e-333321View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.6e-333321View alignment
    2J7T ( Chain: A)
    Crystal Structure Of Human Serine Threonine Kinase-10 Bound To Su11274
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.6e-333321View alignmentSCOP
    MMDB
    CATH
    4AOT ( Chain: A, B)
    Crystal Structure Of Human Serine Threonine Kinase-10 (Lok) Bound To Gw830263a
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.6e-333321View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.6e-333321View alignment
    4USE ( Chain: B, A)
    Human Stk10 (lok) With Sb-633825
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 4.6e-333321View alignmentSCOP
    MMDB
    CATH
    Chain A = 4.6e-333321View alignment
    4EQU ( Chain: A, B)
    Human Stk-10 (Lok) Kinase Domain In Dfg-Out Conformation With Inhibitor Dsa-7
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.6e-333321View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.6e-333321View alignment
    4USD ( Chain: A, B)
    Human Stk10 (lok) With Sb-633825
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.6e-333321View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.6e-333321View alignment
    4USF ( Chain: B, A)
    Human Slk With Sb-440719
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.3e-323221View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.3e-323221View alignment
    2J51 ( Chain: A)
    Crystal Structure Of Human Ste20-Like Kinase Bound To 5- Amino-3-((4-(Aminosulfonyl)phenyl)amino)-N-(2,6- Difluorophenyl)-1h-1,2,4-Triazole-1-Carbothioamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.3e-323221View alignmentSCOP
    MMDB
    CATH
    2JFM ( Chain: A)
    Crystal Structure Of Human Ste20-Like Kinase (Unliganded Form)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-323221View alignmentSCOP
    MMDB
    CATH
    2JFL ( Chain: A)
    Crystal Structure Of Human Ste20-Like Kinase ( Diphosphorylated Form) Bound To 5- Amino-3-((4-( Aminosulfonyl)phenyl)amino)-N-(2,6- Difluorophenyl)-1h-1,2, 4-Triazole-1-Carbothioamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.9e-323221View alignmentSCOP
    MMDB
    CATH
    2CLQ ( Chain: B, A)
    Structure Of Mitogen-Activated Protein Kinase Kinase Kinase 5
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 8.9e-313418View alignmentSCOP
    MMDB
    CATH
    Chain A = 8.9e-313418View alignment
    4BHN ( Chain: B, A)
    Crystal Structures Of Ask1-inhibitor Complexes
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 4.5e-303418View alignmentSCOP
    MMDB
    CATH
    Chain A = 4.5e-303418View alignment
    4BIC ( Chain: B, A)
    Crystal Structures Of Ask1-inhibitor Complexes
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 4.5e-303418View alignmentSCOP
    MMDB
    CATH
    Chain A = 4.5e-303418View alignment
    4BF2 ( Chain: B, A)
    Crystal Structures Of Ask1-inhibitor Complexes
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 4.5e-303418View alignmentSCOP
    MMDB
    CATH
    Chain A = 4.5e-303418View alignment
    4BIB ( Chain: A, B)
    Crystal Structures Of Ask1-inhibitor Complexes
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.5e-303418View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.5e-303418View alignment
    4BID ( Chain: A, B)
    Crystal Structures Of Ask1-inhibitor Complexes
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.5e-303418View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.5e-303418View alignment
    4BIE ( Chain: A, B)
    Crystal Structures Of Ask1-inhibitor Complexes
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.5e-303418View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.5e-303418View alignment
    3VW6 ( Chain: B, A)
    Crystal Structure Of Human Apoptosis Signal-Regulating Kinase 1 (Ask1) With Imidazopyridine Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 7.6e-303419View alignmentSCOP
    MMDB
    CATH
    Chain A = 7.6e-303419View alignment
    2UV2 ( Chain: A)
    Crystal Structure Of Human Ste20-Like Kinase Bound To 4-(4-( 5-Cyclopropyl-1h-Pyrazol-3-Ylamino)-Quinazolin-2-Ylamino)- Phenyl)-Acetonitrile
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.2e-293121View alignmentSCOP
    MMDB
    CATH
    4JDJ ( Chain: A)
    Crystal Structure Of Serine/threonine-protein Kinase Pak 4 F461v Mutant In Complex With Paktide T Peptide Substrate
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.1e-293122View alignmentSCOP
    MMDB
    CATH
    4JDK ( Chain: A)
    Crystal Structure Of Serine/threonine-protein Kinase Pak 4 F461v Mutant In Complex With Paktide S Peptide Substrate
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.1e-293122View alignmentSCOP
    MMDB
    CATH
    2VWI ( Chain: C, B, A, D)
    Structure Of The Osr1 Kinase, A Hypertension Drug Target
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain C = 2.9e-293117View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.9e-293117View alignment
    Chain A = 2.9e-293117View alignment
    Chain D = 2.9e-293117View alignment
    5D9H ( Chain: A, B)
    Crystal Structure Of Spak (stk39) Dimer In The Basal Activity State
  • PDB_Info
  • PDB_Structure
  • Mus musculusChain A = 3.7e-293018View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.7e-293018View alignment
    5DBX ( Chain: A, B)
    Crystal Structure Of Murine Spak(t243d) In Complex With Amppnp
  • PDB_Info
  • PDB_Structure
  • Mus musculusChain A = 6.3e-293018View alignmentSCOP
    MMDB
    CATH
    Chain B = 6.3e-293018View alignment
    4FIE ( Chain: B, A)
    Full-Length Human Pak4
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 6.3e-293122View alignmentSCOP
    MMDB
    CATH
    Chain A = 6.3e-293122View alignment
    4XBR ( Chain: A)
    In Cellulo Crystal Structure Of Pak4 In Complex With Inka
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4JDI ( Chain: A)
    Crystal Structure Of Serine/threonine-protein Kinase Pak 4 In Complex With Paktide S Peptide Substrate
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4JDH ( Chain: A)
    Crystal Structure Of Serine/threonine-protein Kinase Pak 4 In Complex With Paktide T Peptide Substrate
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4FIJ ( Chain: A)
    Catalytic Domain Of Human Pak4
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4FII ( Chain: A)
    Catalytic Domain Of Human Pak4 With Rpkplvdp Peptide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4FIH ( Chain: A)
    Catalytic Domain Of Human Pak4 With Qkftglprqw Peptide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4FIG ( Chain: B, A)
    Catalytic Domain Of Human Pak4
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 6.3e-293122View alignmentSCOP
    MMDB
    CATH
    Chain A = 6.3e-293122View alignment
    2Q0N ( Chain: A)
    Structure Of Human P21 Activating Kinase 4 (Pak4) In Complex With A Consensus Peptide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    2CDZ ( Chain: A)
    Crystal Structure Of The Human P21-Activated Kinase 4 In Complex With Cgp74514a
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    2J0I ( Chain: A)
    Crystal Structure Of The Human P21-Activated Kinase 4
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    2BVA ( Chain: A, B)
    Crystal Structure Of The Human P21-Activated Kinase 4
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 6.3e-293122View alignmentSCOP
    MMDB
    CATH
    Chain B = 6.3e-293122View alignment
    4L67 ( Chain: A)
    Crystal Structure Of Catalytic Domain Of Pak4
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4O0V ( Chain: A)
    Back Pocket Flexibility Provides Group-ii Pak Selectivity For Type 1 Kinase Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4O0X ( Chain: A)
    Back Pocket Flexibility Provides Group-ii Pak Selectivity For Type 1 Kinase Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4O0Y ( Chain: A)
    Back Pocket Flexibility Provides Group-ii Pak Selectivity For Type 1 Kinase Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    5BMS ( Chain: A)
    Crystal Structure Of P21-activated Kinase 4 In Complex With An Inhibitor Compound 29
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    2X4Z ( Chain: A)
    Crystal Structure Of The Human P21-Activated Kinase 4 In Complex With Pf-03758309
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4APP ( Chain: A)
    Crystal Structure Of The Human P21-Activated Kinase 4 In Complex With (S)-N-(5-(3-Benzyl-1-Methylpiperazine-4- Carbonyl)-6,6-Dimethyl-1,4,5,6-Tetrahydropyrrolo(3,4-C) Pyrazol-3-Yl)-3-Phenoxybenzamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4NJD ( Chain: A)
    Structure Of P21-activated Kinase 4 With A Novel Inhibitor Ky-04031
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4XBU ( Chain: A)
    In Vitro Crystal Structure Of Pak4 In Complex With Inka Peptide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.3e-293122View alignmentSCOP
    MMDB
    CATH
    4FIF ( Chain: A, B)
    Catalytic Domain Of Human Pak4 With Rpkplvdp Peptide
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 6.3e-293122View alignmentSCOP
    MMDB
    CATH
    Chain B = 6.3e-293122View alignment
    4ZJI ( Chain: B, A, D, C)
    Pak1 In Complex With 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin- 1-yl)-dibenzodiazepine
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.3e-283221View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.3e-283221View alignment
    Chain D = 1.3e-283221View alignment
    Chain C = 1.3e-283221View alignment
    2J4Z ( Chain: A, B)
    Structure Of Aurora-2 In Complex With Pha-680626
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.3e-283017View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.3e-283017View alignment
    4ZJJ ( Chain: D, B, A, C)
    Pak1 In Complex With (s)-n-(tert-butyl)-3-((2-chloro-5-ethyl-8-fluoro- Dibenzodiazepin-11-yl)amino)pyrrolidine-1-carboxamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain D = 1.3e-283221View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.3e-283221View alignment
    Chain A = 1.3e-283221View alignment
    Chain C = 1.3e-283221View alignment
    3QBN ( Chain: A)
    Structure Of Human Aurora A In Complex With A Diaminopyrimidine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-283117View alignmentSCOP
    MMDB
    CATH
    3DAK ( Chain: A, D, B, C)
    Crystal Structure Of Domain-Swapped Osr1 Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.3e-283118View alignmentSCOP
    MMDB
    CATH
    Chain D = 2.3e-283118View alignment
    Chain B = 2.3e-283118View alignment
    Chain C = 2.3e-283118View alignment
    5AAD ( Chain: A)
    Aurora A Kinase Bound To An Imidazopyridine Inhibitor (7a)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.3e-283117View alignmentSCOP
    MMDB
    CATH
    5AAG ( Chain: A)
    Aurora A Kinase Bound To An Imidazopyridine Inhibitor (14b)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.3e-283117View alignmentSCOP
    MMDB
    CATH
    5AAF ( Chain: A)
    Aurora A Kinase Bound To An Imidazopyridine Inhibitor (14a)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.3e-283117View alignmentSCOP
    MMDB
    CATH
    5AAE ( Chain: A)
    Aurora A Kinase Bound To An Imidazopyridine Inhibitor (14d)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.3e-283117View alignmentSCOP
    MMDB
    CATH
    2DWB ( Chain: A)
    Aurora-A Kinase Complexed With Amppnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.3e-283117View alignmentSCOP
    MMDB
    CATH
    4C3P ( Chain: D, A)
    Structure Of Dephosphorylated Aurora A (122-403) Bound To Tpx2 And Amppcp
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain D = 3.0e-283117View alignmentSCOP
    MMDB
    CATH
    Chain A = 3.0e-283117View alignment
    4C3R ( Chain: A)
    Structure Of Dephosphorylated Aurora A (122-403) Bound To Amppcp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4O0S ( Chain: A)
    Crystal Structures Of Human Kinase Aurora A
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4UTD ( Chain: A)
    Structure Of Dephosphorylated Aurora A (122-403) Bound To Amppcp In An Active Conformation
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4JAI ( Chain: A)
    Crystal Structure Of Aurora Kinase A In Complex With N-{4-[(6-oxo-5,6- Dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4JAJ ( Chain: A)
    Crystal Structure Of Aurora Kinase A In Complex With Benzo[c][1, 8]naphthyridin-6(5h)-one
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    2XNG ( Chain: A)
    Structure Of Aurora-A Bound To A Selective Imidazopyrazine Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4B0G ( Chain: A)
    Complex Of Aurora-a Bound To An Imidazopyridine-based Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4UZD ( Chain: A, B)
    Sar156497 An Exquisitely Selective Inhibitor Of Aurora Kinases
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.0e-283117View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-283117View alignment
    3W16 ( Chain: A)
    Structure Of Aurora Kinase A Complexed To Pyrazole-aminoquinoline Inhibitor Iii
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    3W18 ( Chain: A, B)
    Structure Of Aurora Kinase A Complexed To Benzoimidazole-indazole Inhibitor Xiii
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.0e-283117View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-283117View alignment
    2J50 ( Chain: A, B)
    Structure Of Aurora-2 In Complex With Pha-739358
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.0e-283117View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-283117View alignment
    1MUO ( Chain: A)
    Crystal Structure Of Aurora-2, An Oncogenic Serine- Threonine Kinase
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4ZTR ( Chain: A)
    Human Aurora A Catalytic Domain Bound To Fk1141
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4ZTQ ( Chain: A)
    Human Aurora A Catalytic Domain Bound To Fk932
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4ZS0 ( Chain: A)
    Human Aurora A Catalytic Domain Bound To Sb-6-oh
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4BYJ ( Chain: A)
    Aurora A Kinase Bound To A Highly Selective Imidazopyridine Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4BYI ( Chain: A)
    Aurora A Kinase Bound To A Highly Selective Imidazopyridine Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    2X6E ( Chain: A)
    Aurora-A Bound To An Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    2X6D ( Chain: A)
    Aurora-A Bound To An Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4ZTS ( Chain: A)
    Human Aurora A Catalytic Domain Bound To Fk1142
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-283117View alignmentSCOP
    MMDB
    CATH
    4ZY4 ( Chain: A, B)
    Crystal Structure Of P21 Activated Kinase 1 In Complex With An Inhibitor Compound 4
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 5.1e-283221View alignmentSCOP
    MMDB
    CATH
    Chain B = 5.1e-283221View alignment
    2W1F ( Chain: A)
    Structure Determination Of Aurora Kinase In Complex With Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.1e-283117View alignmentSCOP
    MMDB
    CATH
    4ZLO ( Chain: B, A)
    Serine/threonine-protein Kinase Pak1 Complexed With A Dibenzodiazepine: Identification Of An Allosteric Site On Pak1
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 5.1e-283220View alignmentSCOP
    MMDB
    CATH
    Chain A = 5.1e-283220View alignment
    4ZY5 ( Chain: A, B)
    Crystal Structure Of P21-activated Kinase 1 In Complex With An Inhibitor Compound 17
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 5.1e-283221View alignmentSCOP
    MMDB
    CATH
    Chain B = 5.1e-283221View alignment
    4ZY6 ( Chain: A, B)
    Crystal Structure Of P21-activated Kinase 1 In Complex With An Inhibitor Compound 29
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 5.1e-283221View alignmentSCOP
    MMDB
    CATH
    Chain B = 5.1e-283221View alignment
    1F3M ( Chain: C, D)
    Crystal Structure Of Human SerineTHREONINE KINASE PAK1
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain C = 5.1e-283220View alignmentSCOP
    MMDB
    CATH
    Chain D = 5.1e-283220View alignment
    1YHW ( Chain: A)
    Crystal Structure Of Pak1 Kinase Domain With One Point Mutations (K299r)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.1e-283220View alignmentSCOP
    MMDB
    CATH
    4PRJ ( Chain: A)
    Aurora A Kinase Domain With Compound 2 (n-[1-(3-cyanobenzyl)-1h- Pyrazol-4-yl]-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.1e-283117View alignmentSCOP
    MMDB
    CATH
    3COH ( Chain: A, B)
    Crystal Structure Of Aurora-A In Complex With A Pentacyclic Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 5.1e-283117View alignmentSCOP
    MMDB
    CATH
    Chain B = 5.1e-283117View alignment
    2W1D ( Chain: A)
    Structure Determination Of Aurora Kinase In Complex With Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.1e-283117View alignmentSCOP
    MMDB
    CATH
    2W1E ( Chain: A)
    Structure Determination Of Aurora Kinase In Complex With Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.1e-283117View alignmentSCOP
    MMDB
    CATH
    3Q4Z ( Chain: A, B)
    Structure Of Unphosphorylated Pak1 Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 6.8e-283221View alignmentSCOP
    MMDB
    CATH
    Chain B = 6.8e-283221View alignment
    3Q52 ( Chain: A)
    Structure Of Phosphorylated Pak1 Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-283220View alignmentSCOP
    MMDB
    CATH
    3Q53 ( Chain: A)
    Structure Of Phosphorylated Pak1 Kinase Domain In Complex With Atp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-283220View alignmentSCOP
    MMDB
    CATH
    1MQ4 ( Chain: A)
    Crystal Structure Of Aurora-A Protein Kinase
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-283117View alignmentSCOP
    MMDB
    CATH
    2NP8 ( Chain: A)
    Structural Basis For The Inhibition Of Aurora A Kinase By A Novel Class Of High Affinity Disubstituted Pyrimidine Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-283117View alignmentSCOP
    MMDB
    CATH
    2X81 ( Chain: A)
    Structure Of Aurora A In Complex With Mln8054
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-283117View alignmentSCOP
    MMDB
    CATH
    3MYG ( Chain: A)
    Aurora A Kinase Complexed With Sch 1473759
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-283117View alignmentSCOP
    MMDB
    CATH
    3VAP ( Chain: A)
    Synthesis And Sar Studies Of Imidazo-[1,2-A]-Pyrazine Aurora Kinase Inhibitors With Improved Off Target Kinase Selectivity
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-283117View alignmentSCOP
    MMDB
    CATH
    5DT4 ( Chain: A)
    Aurora A Kinase In Complex With Aa35 And Atp In Space Group P6122
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-283117View alignmentSCOP
    MMDB
    CATH
    3O50 ( Chain: A, B)
    Crystal Structure Of Benzamide 9 Bound To Auroraa
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 6.8e-283117View alignmentSCOP
    MMDB
    CATH
    Chain B = 6.8e-283117View alignment
    3O51 ( Chain: A)
    Crystal Structure Of Anthranilamide 10 Bound To Auroraa
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-283117View alignmentSCOP
    MMDB
    CATH
    3EFW ( Chain: A, B)
    Structure Of Auroraa With Pyridyl-pyrimidine Urea Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 6.8e-283117View alignmentSCOP
    MMDB
    CATH
    Chain B = 6.8e-283117View alignment
    2WTW ( Chain: A)
    Aurora-A Inhibitor Structure (2nd Crystal Form)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.8e-283117View alignmentSCOP
    MMDB
    CATH
    5L8K ( Chain: A)
    Aurora-a Kinase Domain In Complex With Vnar-d01 (crystal Form 2)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens8.7e-283116View alignmentSCOP
    MMDB
    CATH
    5L8J ( Chain: A)
    Aurora-a Kinase Domain In Complex With Vnar-d01 S93r
  • PDB_Info
  • PDB_Structure
  • Homo sapiens8.7e-283116View alignmentSCOP
    MMDB
    CATH
    4CEG ( Chain: A)
    Crystal Structure Of Aurora A 122-403 C290a, C393a Bound To Adp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens8.7e-283116View alignmentSCOP
    MMDB
    CATH
    5L8L ( Chain: A)
    Aurora-a Kinase Domain In Complex With Vnar-d01 (crystal Form 1)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens8.7e-283116View alignmentSCOP
    MMDB
    CATH
    3FY0 ( Chain: A)
    Crystal Structure Of Pak1 Kinase Domain With Ruthenium Complex Dw1
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-273220View alignmentSCOP
    MMDB
    CATH
    4DAW ( Chain: A)
    Crystal Structure Of Pak1 Kinase Domain With The Ruthenium Phthalimide Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-273220View alignmentSCOP
    MMDB
    CATH
    4EQC ( Chain: A)
    Crystal Structure Of Pak1 Kinase Domain In Complex With Frax597 Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-273220View alignmentSCOP
    MMDB
    CATH
    1OL6 ( Chain: A)
    Structure Of Unphosphorylated D274n Mutant Of Aurora-a
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-273117View alignmentSCOP
    MMDB
    CATH
    3FXZ ( Chain: A)
    Crystal Structure Of Pak1 Kinase Domain With Ruthenium Complex Lambda-Fl172
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-273220View alignmentSCOP
    MMDB
    CATH
    2C30 ( Chain: A)
    Crystal Structure Of The Human P21-Activated Kinase 6
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-272926View alignmentSCOP
    MMDB
    CATH
    4KS8 ( Chain: A)
    Pak6 Kinase Domain In Complex With Sunitinib
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-272926View alignmentSCOP
    MMDB
    CATH
    4KS7 ( Chain: A)
    Pak6 Kinase Domain In Complex With Pf-3758309
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-272926View alignmentSCOP
    MMDB
    CATH
    5DFP ( Chain: A)
    Crystal Structure Of Pak1 In Complex With An Inhibitor Compound Frax1036
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-273220View alignmentSCOP
    MMDB
    CATH
    3UOJ ( Chain: B, A)
    Aurora A In Complex With Rpm1715
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.5e-273116View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.5e-273116View alignment
    3UOK ( Chain: A, B)
    Aurora A In Complex With Yl5-81-1
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.5e-273116View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.5e-273116View alignment
    3UOL ( Chain: A, B)
    Aurora A In Complex With So2-162
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.5e-273116View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.5e-273116View alignment
    3UP2 ( Chain: A)
    Aurora A In Complex With Rpm1686
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    3UP7 ( Chain: A)
    Aurora A In Complex With Yl1-038-09
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    4DEA ( Chain: A)
    Aurora A In Complex With Yl1-038-18
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    4DEB ( Chain: A)
    Aurora A In Complex With Rk2-17-01
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    4DED ( Chain: A)
    Aurora A In Complex With Yl1-038-21
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    4DEE ( Chain: A)
    Aurora A In Complex With Adp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    4J8N ( Chain: A, B, C, D)
    Aurora A Kinase Apo
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.5e-273116View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.5e-273116View alignment
    Chain C = 1.5e-273116View alignment
    Chain D = 1.5e-273116View alignment
    2XNE ( Chain: A)
    Structure Of Aurora-A Bound To An Imidazopyrazine Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273117View alignmentSCOP
    MMDB
    CATH
    4O0W ( Chain: A)
    Crystal Structures Of Human Kinase Aurora A
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273117View alignmentSCOP
    MMDB
    CATH
    3D14 ( Chain: A)
    Crystal Structure Of Mouse Aurora A (asn186->gly, Lys240->arg, Met302-leu) In Complex With 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)- Ethyl]- Thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.5e-273117View alignmentSCOP
    MMDB
    CATH
    3DJ5 ( Chain: A)
    Crystal Structure Of The Mouse Aurora-A Catalytic Domain (Asn186->gly, Lys240->arg, Met302->leu) In Complex With Compound 290.
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.5e-273117View alignmentSCOP
    MMDB
    CATH
    3DJ6 ( Chain: A)
    Crystal Structure Of The Mouse Aurora-A Catalytic Domain (Asn186->gly, Lys240->arg, Met302->leu) In Complex With Compound 823.
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.5e-273117View alignmentSCOP
    MMDB
    CATH
    3DJ7 ( Chain: A)
    Crystal Structure Of The Mouse Aurora-A Catalytic Domain (Asn186->gly, Lys240->arg, Met302->leu) In Complex With Compound 130.
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.5e-273117View alignmentSCOP
    MMDB
    CATH
    3D15 ( Chain: A)
    Crystal Structure Of Mouse Aurora A (asn186->gly, Lys240->arg, Met302-leu) In Complex With 1-(3-chloro-phenyl)-3-{5-[2-(thieno[3,2- D]pyrimidin-4-ylamino)- Ethyl]-thiazol-2-yl}-urea [sns-314]
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.5e-273117View alignmentSCOP
    MMDB
    CATH
    3D2I ( Chain: A)
    Crystal Structure Of Mouse Aurora A (Asn186->gly, Lys240-arg, Met302->leu) In Complex With 1-{5-[2-(1-Methyl-1h- Pyrazolo[4,3-D]pyrimidin-7-Ylamino)-Ethyl]-Thiazol-2-Yl}-3- (3-Trifluoromethyl-Phenyl)-Urea
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.5e-273117View alignmentSCOP
    MMDB
    CATH
    3D2K ( Chain: A)
    Crystal Structure Of Mouse Aurora A (Asn186->gly, Lys240-arg, Met302->leu) In Complex With [7-(2-{2-[3-(3-Chloro- Phenyl)-Ureido]-Thiazol-5-Yl}-Ethylamino)-Pyrazolo[4,3- D]pyrimidin-1-Yl]-Acetic Acid
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.5e-273117View alignmentSCOP
    MMDB
    CATH
    2XRU ( Chain: A)
    Aurora-A T288e Complexed With Pha-828300
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    3FDN ( Chain: A)
    Structure-Based Drug Design Of Novel Aurora Kinase A Inhibitors: Structure Basis For Potency And Specificity
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    3K5U ( Chain: A)
    Identification, Sar Studies And X-Ray Cocrystal Analysis Of A Novel Furano-Pyrimidine Aurora Kinase A Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    3M11 ( Chain: A)
    Crystal Structure Of Aurora A Kinase Complexed With Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    4JBO ( Chain: A)
    Novel Aurora Kinase Inhibitors Reveal Mechanisms Of Hurp In Nucleation Of Centrosomal And Kinetochore Microtubules
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    4JBP ( Chain: A)
    Novel Aurora Kinase Inhibitors Reveal Mechanisms Of Hurp In Nucleation Of Centrosomal And Kinetochore Microtubules
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    4JBQ ( Chain: A)
    Novel Aurora Kinase Inhibitors Reveal Mechanisms Of Hurp In Nucleation Of Centrosomal And Kinetochore Microtubules
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    2C6E ( Chain: A, B)
    Aurora A Kinase Activated Mutant (T287d) In Complex With A 5-Aminopyrimidinyl Quinazoline Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.5e-273116View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.5e-273116View alignment
    3LAU ( Chain: A)
    Crystal Structure Of Aurora2 Kinase In Complex With A Gsk3beta Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    4UYN ( Chain: A)
    Sar156497 An Exquisitely Selective Inhibitor Of Aurora Kinases
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    4UZH ( Chain: A)
    Sar156497 An Exquisitely Selective Inhibitor Of Aurora Kinases
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    2C6D ( Chain: A)
    Aurora A Kinase Activated Mutant (T287d) In Complex With Adpnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    3W2C ( Chain: A, C, E, G)
    Structure Of Aurora Kinase A Complexed To Benzoimidazole-indazole Inhibitor Xv
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.5e-273217View alignmentSCOP
    MMDB
    CATH
    Chain C = 1.5e-273217View alignment
    Chain E = 1.5e-273217View alignment
    Chain G = 1.5e-273217View alignment
    4J8M ( Chain: A)
    Aurora A In Complex With Cd532
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    3UNZ ( Chain: A, B)
    Aurora A In Complex With Rpm1679
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.5e-273116View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.5e-273116View alignment
    3UO4 ( Chain: A)
    Aurora A In Complex With Rpm1680
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    3UO5 ( Chain: A)
    Aurora A In Complex With Yl1-038-31
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    3UO6 ( Chain: A, B)
    Aurora A In Complex With Yl5-083
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.5e-273116View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.5e-273116View alignment
    3UOD ( Chain: A)
    Aurora A In Complex With Rpm1693
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-273116View alignmentSCOP
    MMDB
    CATH
    3UOH ( Chain: A, B)
    Aurora A In Complex With Rpm1722
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.5e-273116View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.5e-273116View alignment
    5DEY ( Chain: A, B)
    Crystal Structure Of Pak1 In Complex With An Inhibitor Compound G-5555
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-273220View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-273220View alignment
    5DT3 ( Chain: A)
    Aurora A Kinase In Complex With Atp In Space Group P6122
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273117View alignmentSCOP
    MMDB
    CATH
    3E5A ( Chain: A)
    Crystal Structure Of Aurora A In Complex With Vx-680 And Tpx2
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273117View alignmentSCOP
    MMDB
    CATH
    2WQE ( Chain: A)
    Structure Of S155r Aurora-A Somatic Mutant
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273217View alignmentSCOP
    MMDB
    CATH
    5DNR ( Chain: A)
    Aurora A Kinase In Complex With Atp In Space Group P41212
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273117View alignmentSCOP
    MMDB
    CATH
    4O0R ( Chain: A, B)
    Back Pocket Flexibility Provides Group-ii Pak Selectivity For Type 1 Kinase Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-273220View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-273220View alignment
    4O0T ( Chain: A, B)
    Back Pocket Flexibility Provides Group-ii Pak Selectivity For Type 1 Kinase Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-273220View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-273220View alignment
    5IME ( Chain: A, B)
    Crystal Structure Of P21-activated Kinase 1 (pak1) In Complex With Compound 9
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-273220View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-273220View alignment
    1YHV ( Chain: A)
    Crystal Structure Of Pak1 Kinase Domain With Two Point Mutations (K299r, T423e)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273220View alignmentSCOP
    MMDB
    CATH
    4O0U ( Chain: A)
    Crystal Structures Of Human Kinase Aurora A
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273116View alignmentSCOP
    MMDB
    CATH
    5DOS ( Chain: A)
    Aurora A Kinase In Complex With Aa35 And Atp In Space Group P6122
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273117View alignmentSCOP
    MMDB
    CATH
    5DPV ( Chain: A)
    Aurora A Kinase In Complex With Aa35 And Jnj-7706621 In Space Group P6122
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273117View alignmentSCOP
    MMDB
    CATH
    5DR2 ( Chain: A)
    Aurora A Kinase In Complex With Aa30 And Atp In Space Group P6122
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273117View alignmentSCOP
    MMDB
    CATH
    5DR6 ( Chain: A)
    Aurora A Kinase In Complex With Aa30 And Jnj-7706621 In Space Group P6122
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273117View alignmentSCOP
    MMDB
    CATH
    5DR9 ( Chain: A)
    Aurora A Kinase In Complex With Aa29 And Jnj-7706621 In Space Group P6122
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273117View alignmentSCOP
    MMDB
    CATH
    5DRD ( Chain: A)
    Aurora A Kinase In Complex With Atp In Space Group P6122
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273117View alignmentSCOP
    MMDB
    CATH
    5DT0 ( Chain: A)
    Aurora A Kinase In Complex With Jnj-7706621 In Space Group P6122
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273117View alignmentSCOP
    MMDB
    CATH
    5DN3 ( Chain: A)
    Aurora A In Complex With Atp And Aa35.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.4e-273117View alignmentSCOP
    MMDB
    CATH
    2BMC ( Chain: E, D, C, B, F)
    Aurora-2 T287d T288d Complexed With Pha-680632
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain E = 3.1e-272918View alignmentSCOP
    MMDB
    CATH
    Chain D = 3.1e-272918View alignment
    Chain C = 3.1e-272918View alignment
    Chain B = 3.1e-272918View alignment
    Chain F = 3.1e-272918View alignment
    4P90 ( Chain: A, B)
    Crystal Structure Of The Kinase Domain Of Human Pak1 In Complex With Compound 15
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.1e-273220View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.1e-273220View alignment
    1OL5 ( Chain: A)
    Structure Of Aurora-A 122-403, Phosphorylated On Thr287, Thr288 And Bound To Tpx2 1-43
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.1e-273017View alignmentSCOP
    MMDB
    CATH
    1OL7 ( Chain: A)
    Structure Of Human Aurora-A 122-403 Phosphorylated On Thr287, Thr288
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.1e-273017View alignmentSCOP
    MMDB
    CATH
    4BN1 ( Chain: A)
    Crystal Structure Of V174m Mutant Of Aurora-a Kinase
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.1e-273017View alignmentSCOP
    MMDB
    CATH
    3W10 ( Chain: A)
    Aurora Kinase A Complexed To Pyrazole Aminoquinoline I
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.1e-273017View alignmentSCOP
    MMDB
    CATH
    3NRM ( Chain: A)
    Imidazo[1,2-A]pyrazine-Based Aurora Kinase Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.1e-273017View alignmentSCOP
    MMDB
    CATH
    2WTV ( Chain: A, B, C, D)
    Aurora-A Inhibitor Structure
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 6.9e-273116View alignmentSCOP
    MMDB
    CATH
    Chain B = 6.9e-273116View alignment
    Chain C = 6.9e-273116View alignment
    Chain D = 6.9e-273116View alignment
    3DAJ ( Chain: A)
    Crystal Structure Of Aurora A Complexed With An Inhibitor Discovered Through Site-Directed Dynamic Tethering
  • PDB_Info
  • PDB_Structure
  • Mus musculus6.9e-273117View alignmentSCOP
    MMDB
    CATH
    2W1C ( Chain: A)
    Structure Determination Of Aurora Kinase In Complex With Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.9e-273017View alignmentSCOP
    MMDB
    CATH
    2W1G ( Chain: A)
    Structure Determination Of Aurora Kinase In Complex With Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.9e-273017View alignmentSCOP
    MMDB
    CATH
    2F57 ( Chain: A, B)
    Crystal Structure Of The Human P21-activated Kinase 5
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 9.0e-272924View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.0e-272924View alignment
    5EW9 ( Chain: A)
    Crystal Structure Of Aurora A Kinase Domain Bound To Mk-5108
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.0e-273017View alignmentSCOP
    MMDB
    CATH
    3P9J ( Chain: A)
    Aurora A Kinase Domain With Phthalazinone Pyrazole Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.0e-273017View alignmentSCOP
    MMDB
    CATH
    3H10 ( Chain: D, B, A)
    Aurora A Inhibitor Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain D = 9.0e-273017View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.0e-273017View alignment
    Chain A = 9.0e-273017View alignment
    3H0Z ( Chain: C, B, A)
    Aurora A In Complex With A Bisanilinopyrimidine
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain C = 9.0e-273017View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.0e-273017View alignment
    Chain A = 9.0e-273017View alignment
    3H0Y ( Chain: A)
    Aurora A In Complex With A Bisanilinopyrimidine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.0e-273017View alignmentSCOP
    MMDB
    CATH
    3HA6 ( Chain: A)
    Crystal Structure Of Aurora A In Complex With Tpx2 And Compound 10
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.0e-273017View alignmentSCOP
    MMDB
    CATH
    1U5R ( Chain: B, A)
    Crystal Structure Of The Tao2 Kinase Domain: Activation And Specifity Of A Ste20p Map3k
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicusChain B = 1.1e-263121View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.1e-263121View alignment
    2GCD ( Chain: B, A)
    Tao2 Kinase Domain-Staurosporine Structure
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicusChain B = 1.1e-263121View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.1e-263121View alignment
    1U5Q ( Chain: A, B)
    Crystal Structure Of The Tao2 Kinase Domain: Activation And Specifity Of A Ste20p Map3k
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicusChain A = 1.1e-263121View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-263121View alignment
    4DHF ( Chain: B, A)
    Structure Of Aurora A Mutant Bound To Biogenidec Cpd 15
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.4e-263017View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.4e-263017View alignment
    3R21 ( Chain: A)
    Design, Synthesis, And Biological Evaluation Of Pyrazolopyridine- Sulfonamides As Potent Multiple-Mitotic Kinase (Mmk) Inhibitors (Part I)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-263017View alignmentSCOP
    MMDB
    CATH
    3R22 ( Chain: A)
    Design, Synthesis, And Biological Evaluation Of Pyrazolopyridine- Sulfonamides As Potent Multiple-Mitotic Kinase (Mmk) Inhibitors (Part I)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.4e-263017View alignmentSCOP
    MMDB
    CATH
    3ZDU ( Chain: A)
    Crystal Structure Of The Human Cdkl3 Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.5e-263518View alignmentSCOP
    MMDB
    CATH
    2JAM ( Chain: A, B)
    Crystal Structure Of Human Calmodulin-dependent Protein Kinase I G
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 7.1e-263119View alignmentSCOP
    MMDB
    CATH
    Chain B = 7.1e-263119View alignment
    4BGQ ( Chain: A)
    Crystal Structure Of The Human Cdkl5 Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.2e-263321View alignmentSCOP
    MMDB
    CATH
    4APC ( Chain: A, B)
    Crystal Structure Of Human Nima-Related Kinase 1 (Nek1)
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 7.0e-252723View alignmentSCOP
    MMDB
    CATH
    Chain B = 7.0e-252723View alignment
    4B9D ( Chain: B, A)
    Crystal Structure Of Human Nima-Related Kinase 1 (Nek1) With Inhibitor.
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 7.0e-252723View alignmentSCOP
    MMDB
    CATH
    Chain A = 7.0e-252723View alignment
    5K3Y ( Chain: A, B)
    Crystal Structure Of Aurorab/incenp In Complex With Bi 811283
  • PDB_Info
  • PDB_Structure
  • Xenopus laevisChain A = 1.4e-243016View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.4e-243016View alignment
    3DFA ( Chain: A)
    Crystal Structure Of Kinase Domain Of Calcium-dependent Protein Kinase Cgd3_920 From Cryptosporidium Parvum
  • PDB_Info
  • PDB_Structure
  • Cryptosporidium parvum Iowa II1.4e-243018View alignmentSCOP
    MMDB
    CATH
    2WEI ( Chain: A)
    Crystal Structure Of The Kinase Domain Of Cryptosporidium Parvum Calcium Dependent Protein Kinase In Complex With 3- Mb-Pp1
  • PDB_Info
  • PDB_Structure
  • Cryptosporidium parvum Iowa II1.4e-243018View alignmentSCOP
    MMDB
    CATH
    4B8L ( Chain: A)
    Aurora B Kinase P353g Mutant
  • PDB_Info
  • PDB_Structure
  • Xenopus laevis1.9e-243016View alignmentSCOP
    MMDB
    CATH
    2BFY ( Chain: B, A)
    Complex Of Aurora-b With Incenp And Hesperadin.
  • PDB_Info
  • PDB_Structure
  • Xenopus laevisChain B = 5.5e-242916View alignmentSCOP
    MMDB
    CATH
    Chain A = 5.5e-242916View alignment
    5EYK ( Chain: B, A)
    Crystal Structure Of Aurora B In Complex With Bi 847325
  • PDB_Info
  • PDB_Structure
  • Xenopus laevisChain B = 5.5e-242916View alignmentSCOP
    MMDB
    CATH
    Chain A = 5.5e-242916View alignment
    4B8M ( Chain: A, B)
    Aurora B Kinase In Complex With Vx-680
  • PDB_Info
  • PDB_Structure
  • Xenopus laevisChain A = 7.0e-243016View alignmentSCOP
    MMDB
    CATH
    Chain B = 7.0e-243016View alignment
    2VRX ( Chain: A, B)
    Structure Of Aurora B Kinase In Complex With Zm447439
  • PDB_Info
  • PDB_Structure
  • Xenopus laevisChain A = 7.0e-243016View alignmentSCOP
    MMDB
    CATH
    Chain B = 7.0e-243016View alignment
    2BFX ( Chain: A, B)
    Mechanism Of Aurora-b Activation By Incenp And Inhibition By Hesperadin.
  • PDB_Info
  • PDB_Structure
  • Xenopus laevisChain A = 7.0e-243016View alignmentSCOP
    MMDB
    CATH
    Chain B = 7.0e-243016View alignment
    2VGP ( Chain: A, B)
    Crystal Structure Of Aurora B Kinase In Complex With A Aminothiazole Inhibitor
  • PDB_Info
  • PDB_Structure
  • Xenopus laevisChain A = 7.0e-243016View alignmentSCOP
    MMDB
    CATH
    Chain B = 7.0e-243016View alignment
    2VGO ( Chain: A, B)
    Crystal Structure Of Aurora B Kinase In Complex With Reversine Inhibitor
  • PDB_Info
  • PDB_Structure
  • Xenopus laevisChain A = 7.0e-243016View alignmentSCOP
    MMDB
    CATH
    Chain B = 7.0e-243016View alignment
    3ZTX ( Chain: A, B)
    Aurora Kinase Selective Inhibitors Identified Using A Taxol- Induced Checkpoint Sensitivity Screen.
  • PDB_Info
  • PDB_Structure
  • Xenopus laevisChain A = 7.0e-243016View alignmentSCOP
    MMDB
    CATH
    Chain B = 7.0e-243016View alignment
    4C2V ( Chain: B, A)
    Aurora B Kinase In Complex With The Specific Inhibitor Barasertib
  • PDB_Info
  • PDB_Structure
  • Xenopus laevisChain B = 7.0e-243016View alignmentSCOP
    MMDB
    CATH
    Chain A = 7.0e-243016View alignment
    1A06 ( Chain: A)
    Calmodulin-Dependent Protein Kinase From Rat
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicus7.0e-242821View alignmentSCOP
    MMDB
    CATH
    4C2W ( Chain: A, B)
    Crystal Structure Of Aurora B In Complex With Amp-pnp
  • PDB_Info
  • PDB_Structure
  • Xenopus laevisChain A = 7.0e-243016View alignmentSCOP
    MMDB
    CATH
    Chain B = 7.0e-243016View alignment
    4FG9 ( Chain: B, A)
    Crystal Structure Of Human Calcium/calmodulin-dependent Protein Kinase I 1-320 In Complex With Atp
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 9.0e-242821View alignmentSCOP
    MMDB
    CATH
    Chain A = 9.0e-242821View alignment
    4FGB ( Chain: A)
    Crystal Structure Of Human Calcium/calmodulin-dependent Protein Kinase I Apo Form
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.0e-242821View alignmentSCOP
    MMDB
    CATH
    4FG8 ( Chain: A, B)
    Crystal Structure Of Human Calcium/calmodulin-dependent Protein Kinase I 1-315 In Complex With Atp
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 9.0e-242821View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.0e-242821View alignment
    4FG7 ( Chain: A)
    Crystal Structure Of Human Calcium/calmodulin-dependent Protein Kinase I 1-293 In Complex With Atp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.2e-232921View alignmentSCOP
    MMDB
    CATH
    3MA6 ( Chain: A, B)
    Crystal Structure Of Kinase Domain Of Tgcdpk1 In Presence Of 3brb-Pp1
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondiiChain A = 2.5e-233118View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.5e-233118View alignment
    4AF3 ( Chain: A)
    Human Aurora B Kinase In Complex With Incenp And Vx-680
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.2e-233018View alignmentSCOP
    MMDB
    CATH
    2JC6 ( Chain: C, A)
    Crystal Structure Of Human Calmodulin-Dependent Protein Kinase 1d
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain C = 3.2e-232918View alignmentSCOP
    MMDB
    CATH
    Chain A = 3.2e-232918View alignment
    5IG1 ( Chain: A, B)
    Crystal Structure Of S. Rosetta Camkii Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Salpingoeca rosettaChain A = 4.2e-232919View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.2e-232919View alignment
    2J90 ( Chain: A, B)
    Crystal Structure Of Human Zip Kinase In Complex With A Tetracyclic Pyridone Inhibitor (pyridone 6)
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 5.4e-232818View alignmentSCOP
    MMDB
    CATH
    Chain B = 5.4e-232818View alignment
    4RED ( Chain: B, A)
    Crystal Structure Of Human Ampk Alpha1 Kd-aid With K43a Mutation
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 5.4e-232920View alignmentSCOP
    MMDB
    CATH
    Chain A = 5.4e-232920View alignment
    4IEB ( Chain: A)
    Crystal Structure Of A Gly128met Mutant Of The Toxoplasma Cdpk, Tgme49_101440
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii6.7e-233119View alignmentSCOP
    MMDB
    CATH
    4I5P ( Chain: A)
    Selective & Brain-permeable Polo-like Kinase-2 (plk-2) Inhibitors That Reduce -synuclein Phosphorylation In Rat Brain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.9e-232824View alignmentSCOP
    MMDB
    CATH
    3MFU ( Chain: A)
    Cask-4m Cam Kinase Domain, Amppnp-Mn2+
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.9e-232917View alignmentSCOP
    MMDB
    CATH
    4I6H ( Chain: A)
    Selective & Brain-permeable Polo-like Kinase-2 (plk-2) Inhibitors That Reduce Alpha-synuclein Phosphorylation In Rat Brain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.9e-232824View alignmentSCOP
    MMDB
    CATH
    3MFS ( Chain: A)
    Cask-4m Cam Kinase Domain, Amppnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.9e-232917View alignmentSCOP
    MMDB
    CATH
    3MFR ( Chain: A)
    Cask-4m Cam Kinase Domain, Native
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.9e-232917View alignmentSCOP
    MMDB
    CATH
    4I6F ( Chain: A)
    Selective & Brain-permeable Polo-like Kinase-2 (plk-2) Inhibitors That Reduce -synuclein Phosphorylation In Rat Brain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.9e-232824View alignmentSCOP
    MMDB
    CATH
    4I6B ( Chain: A)
    Selective & Brain-permeable Polo-like Kinase-2 (plk-2) Inhibitors That Reduce -synuclein Phosphorylation In Rat Brain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.9e-232824View alignmentSCOP
    MMDB
    CATH
    4I5M ( Chain: A)
    Selective & Brain-permeable Polo-like Kinase-2 (plk-2) Inhibitors That Reduce -synuclein Phosphorylation In Rat Brain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.9e-232824View alignmentSCOP
    MMDB
    CATH
    3MFT ( Chain: A)
    Cask-4m Cam Kinase Domain, Mn2+
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.9e-232917View alignmentSCOP
    MMDB
    CATH
    3LIJ ( Chain: A)
    Crystal Structure Of Full Length Cpcdpk3 (Cgd5_820) In Complex With Ca2+ And Amppnp
  • PDB_Info
  • PDB_Structure
  • Cryptosporidium parvum Iowa II7.2e-233017View alignmentSCOP
    MMDB
    CATH
    2XKE ( Chain: A)
    Structure Of Nek2 Bound To Aminipyrazine Compound 5
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XNO ( Chain: A)
    Structure Of Nek2 Bound To Cct243779
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XNN ( Chain: A)
    Structure Of Nek2 Bound To Cct242430
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XNM ( Chain: A)
    Structure Of Nek2 Bound To Cct
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    4AAA ( Chain: A)
    Crystal Structure Of The Human Cdkl2 Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223120View alignmentSCOP
    MMDB
    CATH
    4BBM ( Chain: A, B)
    Crystal Structure Of The Human Cdkl2 Kinase Domain With Bound Tcs 2312
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.1e-223120View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-223120View alignment
    2W5A ( Chain: A)
    Human Nek2 Kinase Adp-Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2WQO ( Chain: A)
    Structure Of Nek2 Bound To The Aminopyridine Cct241950
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XK3 ( Chain: A)
    Structure Of Nek2 Bound To Aminopyrazine Compound 35
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XK4 ( Chain: A)
    Structure Of Nek2 Bound To Aminopyrazine Compound 17
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XK6 ( Chain: A)
    Structure Of Nek2 Bound To Aminopyrazine Compound 36
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XK7 ( Chain: A)
    Structure Of Nek2 Bound To Aminopyrazine Compound 23
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XK8 ( Chain: A)
    Structure Of Nek2 Bound To Aminopyrazine Compound 15
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XKC ( Chain: A)
    Structure Of Nek2 Bound To Aminopyrazine Compound 14
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XKD ( Chain: A)
    Structure Of Nek2 Bound To Aminopyrazine Compound 12
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XKF ( Chain: A)
    Structure Of Nek2 Bound To Aminopyrazine Compound 2
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    4AFE ( Chain: A)
    Nek2 Bound To Hybrid Compound 21
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    2XNP ( Chain: A)
    Structure Of Nek2 Bound To Cct244858
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-223516View alignmentSCOP
    MMDB
    CATH
    5A6O ( Chain: B, A)
    Crystal Structure Of The Apo Form Of The Unphosphorylated Human Death Associated Protein Kinase 3 (dapk3)
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.5e-222919View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.5e-222919View alignment
    5A6N ( Chain: B, A)
    Crystal Structure Of Human Death Associated Protein Kinase 3 (dapk3) In Complex With Compound 2
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.5e-222919View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.5e-222919View alignment
    3BHY ( Chain: A)
    Crystal Structure Of Human Death Associated Protein Kinase 3 (dapk3) In Complex With A Beta-carboline Ligand
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-222919View alignmentSCOP
    MMDB
    CATH
    3BQR ( Chain: A)
    Crystal Structure Of Human Death Associated Protein Kinase 3 (Dapk3) In Complex With An Imidazo-Pyridazine Ligand
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-222919View alignmentSCOP
    MMDB
    CATH
    3IGO ( Chain: A)
    Crystal Structure Of Cryptosporidium Parvum Cdpk1, Cgd3_920
  • PDB_Info
  • PDB_Structure
  • Cryptosporidium parvum Iowa II1.5e-223018View alignmentSCOP
    MMDB
    CATH
    3MWU ( Chain: A)
    Activated Calcium-Dependent Protein Kinase 1 From Cryptosporidium Parvum (Cpcdpk1) In Complex With Bumped Kinase Inhibitor Rm-1-95
  • PDB_Info
  • PDB_Structure
  • Cryptosporidium parvum Iowa II1.5e-223018View alignmentSCOP
    MMDB
    CATH
    3NCG ( Chain: A)
    Activated Calcium-Dependent Protein Kinase 1 From Cryptosporidium Parvum (Cpcdpk1) In Complex With Bumped Kinase Inhibitor Nm-Pp1
  • PDB_Info
  • PDB_Structure
  • Cryptosporidium parvum Iowa II1.5e-223018View alignmentSCOP
    MMDB
    CATH
    4Y5Q ( Chain: A)
    Activated Calcium-dependent Protein Kinase 1 From Cryptosporidium Parvum (cpcdpk1) In Complex With Amp
  • PDB_Info
  • PDB_Structure
  • Cryptosporidium parvum Iowa II1.5e-223018View alignmentSCOP
    MMDB
    CATH
    1FOT ( Chain: A)
    Structure Of The Unliganded Camp-Dependent Protein Kinase Catalytic Subunit From Saccharomyces Cerevisiae
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.9e-222919View alignmentSCOP
    MMDB
    CATH
    2JAV ( Chain: A)
    Human Kinase With Pyrrole-Indolinone Ligand
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.0e-223515View alignmentSCOP
    MMDB
    CATH
    3DXN ( Chain: A)
    Crystal Structure Of The Calcium-dependent Kinase From Toxoplasma Gondii, 541.m00134, Kinase Domain.
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.0e-222917View alignmentSCOP
    MMDB
    CATH
    2W5H ( Chain: A)
    Human Nek2 Kinase Apo
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.0e-223515View alignmentSCOP
    MMDB
    CATH
    2W5B ( Chain: A)
    Human Nek2 Kinase Atpgammas-bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.0e-223515View alignmentSCOP
    MMDB
    CATH
    3I79 ( Chain: A)
    Calcium-dependent Protein Kinase 1 From Toxoplasma Gondii (tgcdpk1)
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    3I7B ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Bumped Kinase Inhibitor Nm-Pp1
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    3N51 ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Bumped Kinase Inhibitor Rm-1-95
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    3SX9 ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Bumped Kinase Inhibitor, Rm-1-132
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    3SXF ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Bumped Kinase Inhibitor, Rm-1-89
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    3T3U ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Bumped Kinase Inhibitor, Rm-1-130
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    3T3V ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Bumped Kinase Inhibitor, Rm-1-87
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    3UPX ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Inhibitor Uw1300
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    3UPZ ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Bumpless Bki Analog Uw1243
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    3V51 ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Inhibitor Rm-1-176
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    3V5P ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Inhibitor Uw1288
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    3V5T ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Inhibitor Uw1299
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    4M84 ( Chain: A)
    Calcium-dependent Protein Kinase 1 From Toxoplasma Gondii (tgcdpk1) In Complex With Inhibitor Uw1455
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    4JBV ( Chain: A)
    Calcium-dependent Protein Kinase 1 From Toxoplasma Gondii (tgcdpk1) In Complex With Inhibitor Uw1268
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    4ONA ( Chain: A)
    Calcium-dependent Protein Kinase 1 From Toxoplasma Gondii (tgcdpk1) In Complex With Inhibitor Uw1517
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    4TZR ( Chain: A)
    Calcium-dependent Protein Kinase 1 From Toxoplasma Gondii (tgcdpk1) In Complex With Inhibitor Uw1561
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    4WG3 ( Chain: A)
    Calcium-dependent Protein Kinase 1 From Toxoplasma Gondii (tgcdpk1) In Complex With Inhibitor Uw1610
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    4WG4 ( Chain: A)
    Calcium-dependent Protein Kinase 1 From Toxoplasma Gondii (tgcdpk1) In Complex With Inhibitor Uw1613
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    4WG5 ( Chain: A)
    Calcium-dependent Protein Kinase 1 From Toxoplasma Gondii (tgcdpk1) In Complex With Inhibitor Uw1647
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    4YJN ( Chain: A)
    Calcium-dependent Protein Kinase 1 From Toxoplasma Gondii (tgcdpk1) In Complex With Inhibitor Uw1639
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii4.4e-223020View alignmentSCOP
    MMDB
    CATH
    4IH8 ( Chain: A)
    Crystal Structure Of Tgcdpk1 With Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii5.4e-223020View alignmentSCOP
    MMDB
    CATH
    4IFG ( Chain: A)
    Crystal Structure Of Tgcdpk1 With Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii5.4e-223020View alignmentSCOP
    MMDB
    CATH
    4IHP ( Chain: A)
    Crystal Structure Of Tgcdpk1 With Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii5.4e-223020View alignmentSCOP
    MMDB
    CATH
    3KU2 ( Chain: A)
    Crystal Structure Of Inactivated Form Of Cdpk1 From Toxoplasma Gondii, Tgme49.101440
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii5.4e-223020View alignmentSCOP
    MMDB
    CATH
    3HX4 ( Chain: A)
    Crystal Structure Of Cdpk1 Of Toxoplasma Gondii, Tgme49_101440, In Presence Of Calcium
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii5.4e-223020View alignmentSCOP
    MMDB
    CATH
    4YGA ( Chain: G, E, C, A)
    Cdpk1, From Toxoplasma Gondii, Bound To Inhibitory Vhh-1b7
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondiiChain G = 5.8e-223020View alignmentSCOP
    MMDB
    CATH
    Chain E = 5.8e-223020View alignment
    Chain C = 5.8e-223020View alignment
    Chain A = 5.8e-223020View alignment
    4M97 ( Chain: A)
    Calcium-dependent Protein Kinase 1 From Neospora Caninum
  • PDB_Info
  • PDB_Structure
  • Neospora caninum Liverpool5.8e-223020View alignmentSCOP
    MMDB
    CATH
    4MX9 ( Chain: A)
    Cdpk1 From Neospora Caninum In Complex With Inhibitor Uw1294
  • PDB_Info
  • PDB_Structure
  • Neospora caninum Liverpool5.8e-223020View alignmentSCOP
    MMDB
    CATH
    4MXA ( Chain: A)
    Cdpk1 From Neospora Caninum In Complex With Inhibitor Rm-1-132
  • PDB_Info
  • PDB_Structure
  • Neospora caninum Liverpool5.8e-223020View alignmentSCOP
    MMDB
    CATH
    5DVT ( Chain: A)
    Crystal Structure Of Tgcdpk1 From Toxoplasma Gondii Complexed With 5gb
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii6.0e-223020View alignmentSCOP
    MMDB
    CATH
    5DVU ( Chain: A)
    Crystal Structure Of Tgcdpk1 From Toxoplasma Gondii Complexed With 5ga
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii6.0e-223020View alignmentSCOP
    MMDB
    CATH
    5JMS ( Chain: A)
    Crystal Structure Of Tgcdpk1 Bound To Cgp060476
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii6.0e-223020View alignmentSCOP
    MMDB
    CATH
    5JN2 ( Chain: A)
    Crystal Structure Of Tgcdpk1 Bound To Nvpacu106
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii6.0e-223020View alignmentSCOP
    MMDB
    CATH
    5DVR ( Chain: A)
    Crystal Structure Of Tgcdpk1 From Toxoplasma Gondii Complexed With Gw780159x
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii6.0e-223020View alignmentSCOP
    MMDB
    CATH
    4M8T ( Chain: A)
    Rsk2 T493m C-terminal Kinase Domain In Complex With 3-(3-(1h-pyrazol- 4-yl)phenyl)-2-cyanoacrylamide
  • PDB_Info
  • PDB_Structure
  • Mus musculus6.7e-222820View alignmentSCOP
    MMDB
    CATH
    4MAO ( Chain: A)
    Rsk2 T493m C-terminal Kinase Domain In Complex With Rmm58
  • PDB_Info
  • PDB_Structure
  • Mus musculus6.7e-222820View alignmentSCOP
    MMDB
    CATH
    4JG8 ( Chain: A)
    Structure Of Rsk2 T493m Ctd Mutant Bound To 2-cyano-n-(1-hydroxy-2- Methylpropan-2-yl)-3-(3-(3,4,5-trimethoxyphenyl)-1h-indazol-5-yl) Acrylamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens6.7e-222820View alignmentSCOP
    MMDB
    CATH
    4TL0 ( Chain: A)
    Crystal Structure Of Death-associated Protein Kinase 1 With A Crucial Phosphomimicking Mutation
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.0e-212720View alignmentSCOP
    MMDB
    CATH
    2XUU ( Chain: A)
    Crystal Structure Of A Dap-kinase 1 Mutant
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.0e-212720View alignmentSCOP
    MMDB
    CATH
    2QNJ ( Chain: A, B)
    Kinase And Ubiquitin-Associated Domains Of Mark3PAR-1
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.0e-212924View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.0e-212924View alignment
    2XZS ( Chain: B, A)
    Death Associated Protein Kinase 1 Residues 1-312
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.3e-212720View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.3e-212720View alignment
    4A4X ( Chain: A)
    Nek2-Ede Bound To Cct248662
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.3e-213416View alignmentSCOP
    MMDB
    CATH
    2X0G ( Chain: A)
    X-ray Structure Of A Dap-kinase Calmodulin Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.3e-212720View alignmentSCOP
    MMDB
    CATH
    4YUQ ( Chain: B, A)
    Cdpk1 From Eimeria Tenella In Complex With Inhibitor Uw1354
  • PDB_Info
  • PDB_Structure
  • Eimeria tenellaChain B = 1.7e-213019View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.7e-213019View alignment
    4YZB ( Chain: B, A)
    Cdpk1 From Eimeria Tenella In Complex With Inhibitor Uw1521
  • PDB_Info
  • PDB_Structure
  • Eimeria tenellaChain B = 1.7e-213019View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.7e-213019View alignment
    4YSJ ( Chain: A, B)
    Calcium-dependent Protein Kinase From Eimeria Tenella In Complex With Adp
  • PDB_Info
  • PDB_Structure
  • Eimeria tenellaChain A = 1.7e-213019View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-213019View alignment
    4YSM ( Chain: B, A)
    Calcium-dependent Protein Kinase From Eimeria Tenella
  • PDB_Info
  • PDB_Structure
  • Eimeria tenellaChain B = 1.7e-213019View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.7e-213019View alignment
    4UV0 ( Chain: A)
    Structure Of A Semisynthetic Phosphorylated Dapk
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.9e-212720View alignmentSCOP
    MMDB
    CATH
    5ES1 ( Chain: A)
    Crystal Structure Of Microtubule Affinity-regulating Kinase 4 Catalytic Domain In Complex With A Pyrazolopyrimidine Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.9e-212924View alignmentSCOP
    MMDB
    CATH
    4PDS ( Chain: A, B)
    Crystal Structure Of Rad53 Kinase Domain And Scd2 In Complex With Amppnp
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain A = 1.9e-212916View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.9e-212916View alignment
    4PDP ( Chain: B, A)
    Crystal Structure Of Rad53 Kinase Domain And Scd2
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain B = 1.9e-212916View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.9e-212916View alignment
    4KRD ( Chain: A)
    Crystal Structure Of Pho85-pcl10 Complex
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae S288c2.3e-212920View alignmentSCOP
    MMDB
    CATH
    1YRP ( Chain: A, B)
    Catalytic Domain Of Human Zip Kinase Phosphorylated At Thr265
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.3e-212820View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.3e-212820View alignment
    4KRC ( Chain: A)
    Crystal Structure Of Pho85-pcl10-atp-gamma-s Complex
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae S288c2.3e-212920View alignmentSCOP
    MMDB
    CATH
    2PMI ( Chain: C, A)
    Structure Of The Pho85-Pho80 Cdk-Cyclin Complex Of The Phosphate- Responsive Signal Transduction Pathway With Bound Atp-Gamma-S
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain C = 2.3e-212920View alignmentSCOP
    MMDB
    CATH
    Chain A = 2.3e-212920View alignment
    2PK9 ( Chain: C, A)
    Structure Of The Pho85-pho80 Cdk-cyclin Complex Of The Phosphate-responsive Signal Transduction Pathway
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain C = 2.3e-212920View alignmentSCOP
    MMDB
    CATH
    Chain A = 2.3e-212920View alignment
    2QR8 ( Chain: A)
    2.0a X-ray Structure Of C-terminal Kinase Domain Of P90 Ribosomal S6 Kinase 2 (rsk2)
  • PDB_Info
  • PDB_Structure
  • Mus musculus3.0e-212721View alignmentSCOP
    MMDB
    CATH
    4D9U ( Chain: A)
    Rsk2 C-Terminal Kinase Domain, (E)-Tert-Butyl 3-(4-Amino-7-(3- Hydroxypropyl)-5-P-Tolyl-7h-Pyrrolo[2,3-D]pyrimidin-6-Yl)-2- Cyanoacrylate
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-212721View alignmentSCOP
    MMDB
    CATH
    4D9T ( Chain: A)
    Rsk2 C-Terminal Kinase Domain With Inhibitor (E)-Methyl 3-(4-Amino-7- (3-Hydroxypropyl)-5-P-Tolyl-7h-Pyrrolo[2,3-D]pyrimidin-6-Yl)-2- Cyanoacrylate
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-212721View alignmentSCOP
    MMDB
    CATH
    5DYK ( Chain: A)
    Crystal Structure Of Pf3d7_1436600
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparum3.3e-213317View alignmentSCOP
    MMDB
    CATH
    3I7C ( Chain: A)
    Calcium-dependent Protein Kinase 1 From Toxoplasma Gondii (tgcdpk1) In Complex With Bumped Kinase Inhibitor Na-pp2
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii3.6e-213019View alignmentSCOP
    MMDB
    CATH
    3NYV ( Chain: A)
    Calcium-Dependent Protein Kinase 1 From Toxoplasma Gondii (Tgcdpk1) In Complex With Non-Specific Inhibitor Whi-P180
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii3.6e-213019View alignmentSCOP
    MMDB
    CATH
    3A8X ( Chain: B, A)
    Crystal Structure Of Pkciota Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 3.9e-212821View alignmentSCOP
    MMDB
    CATH
    Chain A = 3.9e-212821View alignment
    3A8W ( Chain: B, A)
    Crystal Structure Of Pkciota Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 3.9e-212821View alignmentSCOP
    MMDB
    CATH
    Chain A = 3.9e-212821View alignment
    4REW ( Chain: A)
    Crystal Structure Of The Non-phosphorylated Human Alpha1 Beta2 Gamma1 Holo-ampk Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.2e-212920View alignmentSCOP
    MMDB
    CATH
    1KOB ( Chain: A, B)
    Twitchin Kinase Fragment (Aplysia), Autoregulated Protein Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Aplysia californicaChain A = 4.9e-212622View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.9e-212622View alignment
    4B4L ( Chain: A)
    Crystal Structure Of An Ard Dap-kinase 1 Mutant
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.1e-212621View alignmentSCOP
    MMDB
    CATH
    3FE3 ( Chain: A, B)
    Crystal Structure Of The Kinase Mark3PAR-1: T211a-S215a Double Mutant
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 5.1e-212824View alignmentSCOP
    MMDB
    CATH
    Chain B = 5.1e-212824View alignment
    3IS5 ( Chain: F, E, D, C, B, A)
    Crystal Structure Of Cdpk Kinase Domain From Toxoplasma Gondii, Tgme49_018720
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii ME49Chain F = 5.1e-212820View alignmentSCOP
    MMDB
    CATH
    Chain E = 5.1e-212820View alignment
    Chain D = 5.1e-212820View alignment
    Chain C = 5.1e-212820View alignment
    Chain B = 5.1e-212820View alignment
    Chain A = 5.1e-212820View alignment
    2Z7S ( Chain: A)
    Crystal Structure Of The N-Terminal Kinase Domain Of Human Rsk1 Bound To Purvalnol A
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.1e-213222View alignmentSCOP
    MMDB
    CATH
    2Z7R ( Chain: A)
    Crystal Structure Of The N-Terminal Kinase Domain Of Human Rsk1 Bound To Staurosporine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.1e-213222View alignmentSCOP
    MMDB
    CATH
    2Z7Q ( Chain: A)
    Crystal Structure Of The N-Terminal Kinase Domain Of Human Rsk-1 Bound To Amp-Pcp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.1e-213222View alignmentSCOP
    MMDB
    CATH
    2WQN ( Chain: A)
    Structure Of Adp-Bound Human Nek7
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.1e-212820View alignmentSCOP
    MMDB
    CATH
    2WQM ( Chain: A)
    Structure Of Apo Human Nek7
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.1e-212820View alignmentSCOP
    MMDB
    CATH
    4FR4 ( Chain: B, C, D, E, F, A)
    Crystal Structure Of Human SerineTHREONINE-Protein Kinase 32a (Yank1)
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 5.9e-212920View alignmentSCOP
    MMDB
    CATH
    Chain C = 5.9e-212920View alignment
    Chain D = 5.9e-212920View alignment
    Chain E = 5.9e-212920View alignment
    Chain F = 5.9e-212920View alignment
    Chain A = 5.9e-212920View alignment
    2HAK ( Chain: A, B, C, H, D, G, F, E)
    Catalytic And Ubiqutin-Associated Domains Of Mark1PAR-1
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 6.6e-212924View alignmentSCOP
    MMDB
    CATH
    Chain B = 6.6e-212924View alignment
    Chain C = 6.6e-212924View alignment
    Chain H = 6.6e-212924View alignment
    Chain D = 6.6e-212924View alignment
    Chain G = 6.6e-212924View alignment
    Chain F = 6.6e-212924View alignment
    Chain E = 6.6e-212924View alignment
    4NIF ( Chain: A, D)
    Heterodimeric Structure Of Erk2 And Rsk1
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 8.4e-212821View alignmentSCOP
    MMDB
    CATH
    Chain D = 8.4e-212821View alignment
    2WNT ( Chain: A, B)
    Crystal Structure Of The Human Ribosomal Protein S6 Kinase
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 8.4e-212821View alignmentSCOP
    MMDB
    CATH
    Chain B = 8.4e-212821View alignment
    2W4K ( Chain: A)
    X-ray Structure Of A Dap-kinase 2-302
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-202621View alignmentSCOP
    MMDB
    CATH
    2Y0A ( Chain: A)
    Structure Of Dapk1 Construct Residues 1-304
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-202621View alignmentSCOP
    MMDB
    CATH
    3H4J ( Chain: A, B)
    Crystal Structure Of Pombe Ampk Kdaid Fragment
  • PDB_Info
  • PDB_Structure
  • Schizosaccharomyces pombeChain A = 1.1e-202820View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.1e-202820View alignment
    1ZYD ( Chain: B, A)
    Crystal Structure Of Eif2alpha Protein Kinase Gcn2: Wild- Type Complexed With Atp.
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain B = 1.1e-202818View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.1e-202818View alignment
    1ZYC ( Chain: D, C, B, A)
    Crystal Structure Of Eif2alpha Protein Kinase Gcn2: Wild- Type In Apo Form.
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain D = 1.1e-202818View alignmentSCOP
    MMDB
    CATH
    Chain C = 1.1e-202818View alignment
    Chain B = 1.1e-202818View alignment
    Chain A = 1.1e-202818View alignment
    5F0A ( Chain: A)
    Crystal Structure Of Pvx_084705 With Bound 1-tert-butyl-3-(3- Chlorophenoxy)-1h-pyrazolo[3,4-d]pyrimidin-4-amine Inhibitor
  • PDB_Info
  • PDB_Structure
  • Plasmodium vivax Sal-11.2e-203218View alignmentSCOP
    MMDB
    CATH
    5DYL ( Chain: A)
    Crystal Structure Of Pvx_084705
  • PDB_Info
  • PDB_Structure
  • Plasmodium vivax1.2e-203218View alignmentSCOP
    MMDB
    CATH
    5DE2 ( Chain: B, A)
    Structural Mechanism Of Nek7 Activation By Nek9-induced Dimerisation
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.4e-202721View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.4e-202721View alignment
    3ZH8 ( Chain: A, B, C)
    A Novel Small Molecule Apkc Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.5e-202821View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.5e-202821View alignment
    Chain C = 1.5e-202821View alignment
    4RER ( Chain: A)
    Crystal Structure Of The Phosphorylated Human Alpha1 Beta2 Gamma1 Holo-ampk Complex Bound To Amp And Cyclodextrin
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-202920View alignmentSCOP
    MMDB
    CATH
    3A2C ( Chain: A, B, C, D, E, F, G, H, I, J, K, L)
    Crystal Structure Of A Pyrazolopyrimidine Inhibitor Complex Mapkap Kinase-2 (Mk2)
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-203019View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-203019View alignment
    Chain C = 1.7e-203019View alignment
    Chain D = 1.7e-203019View alignment
    Chain E = 1.7e-203019View alignment
    Chain F = 1.7e-203019View alignment
    Chain G = 1.7e-203019View alignment
    Chain H = 1.7e-203019View alignment
    Chain I = 1.7e-203019View alignment
    Chain J = 1.7e-203019View alignment
    Chain K = 1.7e-203019View alignment
    Chain L = 1.7e-203019View alignment
    3WI6 ( Chain: A, B, C, D, E, F)
    Crystal Structure Of Mapkap Kinase-2 (mk2) In Complex With Non- Selective Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-203019View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-203019View alignment
    Chain C = 1.7e-203019View alignment
    Chain D = 1.7e-203019View alignment
    Chain E = 1.7e-203019View alignment
    Chain F = 1.7e-203019View alignment
    3FPM ( Chain: A)
    Crystal Structure Of A Squarate Inhibitor Bound To Mapkap Kinase-2
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-203019View alignmentSCOP
    MMDB
    CATH
    2JBO ( Chain: A)
    Protein Kinase Mk2 In Complex With An Inhibitor (Crystal Form-1, Soaking)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-203019View alignmentSCOP
    MMDB
    CATH
    2JBP ( Chain: A, B, C, D, E, F, G, H, I, J, K, L)
    Protein Kinase Mk2 In Complex With An Inhibitor (crystal Form-2, Co-crystallization)
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-203019View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-203019View alignment
    Chain C = 1.7e-203019View alignment
    Chain D = 1.7e-203019View alignment
    Chain E = 1.7e-203019View alignment
    Chain F = 1.7e-203019View alignment
    Chain G = 1.7e-203019View alignment
    Chain H = 1.7e-203019View alignment
    Chain I = 1.7e-203019View alignment
    Chain J = 1.7e-203019View alignment
    Chain K = 1.7e-203019View alignment
    Chain L = 1.7e-203019View alignment
    2P3G ( Chain: X)
    Crystal Structure Of A Pyrrolopyridine Inhibitor Bound To Mapkap Kinase-2
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-203019View alignmentSCOP
    MMDB
    CATH
    3FYJ ( Chain: X)
    Crystal Structure Of An Optimzied Benzothiophene Inhibitor Bound To Mapkap Kinase-2 (Mk-2)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-203019View alignmentSCOP
    MMDB
    CATH
    3FYK ( Chain: X)
    Crystal Structure Of A Benzthiophene Lead Bound To Mapkap Kinase-2 (Mk-2)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-203019View alignmentSCOP
    MMDB
    CATH
    3GOK ( Chain: A, B, C, D, E, F, G, H, I, J, K, L)
    Binding Site Mapping Of Protein Ligands
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-203019View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-203019View alignment
    Chain C = 1.7e-203019View alignment
    Chain D = 1.7e-203019View alignment
    Chain E = 1.7e-203019View alignment
    Chain F = 1.7e-203019View alignment
    Chain G = 1.7e-203019View alignment
    Chain H = 1.7e-203019View alignment
    Chain I = 1.7e-203019View alignment
    Chain J = 1.7e-203019View alignment
    Chain K = 1.7e-203019View alignment
    Chain L = 1.7e-203019View alignment
    3UBD ( Chain: A)
    Structure Of N-Terminal Domain Of Rsk2 Kinase In Complex With Flavonoid Glycoside Sl0101
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.7e-203124View alignmentSCOP
    MMDB
    CATH
    4EL9 ( Chain: A)
    Structure Of N-Terminal Kinase Domain Of Rsk2 With Afzelin
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.7e-203124View alignmentSCOP
    MMDB
    CATH
    4GUE ( Chain: A)
    Structure Of N-terminal Kinase Domain Of Rsk2 With Flavonoid Glycoside Quercitrin
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.7e-203124View alignmentSCOP
    MMDB
    CATH
    4NW5 ( Chain: A)
    Rsk2 N-terminal Kinase In Complex With 2-amino-7-substituted Benzoxazole Compound 8
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-203124View alignmentSCOP
    MMDB
    CATH
    4NW6 ( Chain: A)
    Rsk2 N-terminal Kinase In Complex With 2-amino-7-substituted Benzoxazole Compound 27
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-203124View alignmentSCOP
    MMDB
    CATH
    4NUS ( Chain: A)
    Rsk2 N-terminal Kinase In Complex With Ljh685
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-203124View alignmentSCOP
    MMDB
    CATH
    5D9L ( Chain: A)
    Rsk2 N-terminal Kinase In Complex With Bis-phenol Pyrazole
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-203124View alignmentSCOP
    MMDB
    CATH
    3G51 ( Chain: A)
    Structural Diversity Of The Active Conformation Of The N- Terminal Kinase Domain Of P90 Ribosomal S6 Kinase 2
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.7e-203124View alignmentSCOP
    MMDB
    CATH
    5D9K ( Chain: A, B)
    Rsk2 N-terminal Kinase In Complex With Bi-d1870
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-203124View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-203124View alignment
    3R2B ( Chain: A, B, C, D, E, F, G, H, I, J, K, L)
    Mk2 Kinase Bound To Compound 5b
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-203019View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-203019View alignment
    Chain C = 1.7e-203019View alignment
    Chain D = 1.7e-203019View alignment
    Chain E = 1.7e-203019View alignment
    Chain F = 1.7e-203019View alignment
    Chain G = 1.7e-203019View alignment
    Chain H = 1.7e-203019View alignment
    Chain I = 1.7e-203019View alignment
    Chain J = 1.7e-203019View alignment
    Chain K = 1.7e-203019View alignment
    Chain L = 1.7e-203019View alignment
    3R2Y ( Chain: A)
    Mk2 Kinase Bound To Compound 1
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-203019View alignmentSCOP
    MMDB
    CATH
    3R30 ( Chain: A)
    Mk2 Kinase Bound To Compound 2
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-203019View alignmentSCOP
    MMDB
    CATH
    2PZY ( Chain: A, B, C, D)
    Structure Of Mk2 Complexed With Compound 76
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-203019View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-203019View alignment
    Chain C = 1.7e-203019View alignment
    Chain D = 1.7e-203019View alignment
    3KC3 ( Chain: A, B, C, D, E, F, G, H, I, J, K, L)
    Mk2 Complexed To Inhibitor N4-(7-(Benzofuran-2-Yl)-1h-Indazol-5-Yl) Pyrimidine-2,4-Diamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-203019View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-203019View alignment
    Chain C = 1.7e-203019View alignment
    Chain D = 1.7e-203019View alignment
    Chain E = 1.7e-203019View alignment
    Chain F = 1.7e-203019View alignment
    Chain G = 1.7e-203019View alignment
    Chain H = 1.7e-203019View alignment
    Chain I = 1.7e-203019View alignment
    Chain J = 1.7e-203019View alignment
    Chain K = 1.7e-203019View alignment
    Chain L = 1.7e-203019View alignment
    3KL8 ( Chain: A, C, E, G, I)
    Camkiintide Inhibitor Complex
  • PDB_Info
  • PDB_Structure
  • Caenorhabditis elegansChain A = 2.2e-203018View alignmentSCOP
    MMDB
    CATH
    Chain C = 2.2e-203018View alignment
    Chain E = 2.2e-203018View alignment
    Chain G = 2.2e-203018View alignment
    Chain I = 2.2e-203018View alignment
    3KK9 ( Chain: A)
    Camkii Substrate Complex B
  • PDB_Info
  • PDB_Structure
  • Caenorhabditis elegans2.2e-203018View alignmentSCOP
    MMDB
    CATH
    3KK8 ( Chain: A)
    Camkii Substrate Complex A
  • PDB_Info
  • PDB_Structure
  • Caenorhabditis elegans2.2e-203018View alignmentSCOP
    MMDB
    CATH
    4CFH ( Chain: A)
    Structure Of An Active Form Of Mammalian Ampk
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicus2.5e-202920View alignmentSCOP
    MMDB
    CATH
    4QFG ( Chain: A)
    Structure Of Ampk In Complex With Staurosporine Inhibitor And In The Absence Of A Synthetic Activator
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicus2.7e-202920View alignmentSCOP
    MMDB
    CATH
    4QFR ( Chain: A)
    Structure Of Ampk In Complex With Cl-a769662 Activator And Staurosporine Inhibitor
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicus2.7e-202920View alignmentSCOP
    MMDB
    CATH
    4QFS ( Chain: A)
    Structure Of Ampk In Complex With Br2-a769662core Activator And Staurosporine Inhibitor
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicus2.7e-202920View alignmentSCOP
    MMDB
    CATH
    5KQ5 ( Chain: A)
    Ampk Bound To Allosteric Activator
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicus2.7e-202920View alignmentSCOP
    MMDB
    CATH
    4JG6 ( Chain: A)
    Rsk2 Ctd Bound To 2-cyano-3-(1h-indazol-5-yl)acrylamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.8e-202721View alignmentSCOP
    MMDB
    CATH
    4JG7 ( Chain: A)
    Structure Of Rsk2 Ctd Bound To 3-(3-(1h-pyrrolo[2,3-b]pyridine-3- Carbonyl)phenyl)-2-cyanoacrylamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.8e-202721View alignmentSCOP
    MMDB
    CATH
    4UN0 ( Chain: C, D)
    Crystal Structure Of The Human Cdk12-cyclink Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain C = 3.0e-203017View alignmentSCOP
    MMDB
    CATH
    Chain D = 3.0e-203017View alignment
    1V0P ( Chain: B, A)
    Structure Of P. Falciparum Pfpk5-Purvalanol B Ligand Complex
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparumChain B = 3.0e-203317View alignmentSCOP
    MMDB
    CATH
    Chain A = 3.0e-203317View alignment
    4CQE ( Chain: A, B)
    B-raf Kinase V600e Mutant In Complex With A Diarylthiazole B-raf Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.0e-203317View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-203317View alignment
    4XV1 ( Chain: A, B)
    B-raf Kinase V600e Oncogenic Mutant In Complex With Plx7904
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.0e-203317View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-203317View alignment
    4XV2 ( Chain: A, B)
    B-raf Kinase V600e Oncogenic Mutant In Complex With Dabrafenib
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.0e-203317View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-203317View alignment
    4XV3 ( Chain: A, B)
    B-raf Kinase V600e Oncogenic Mutant In Complex With Plx7922
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.0e-203317View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-203317View alignment
    4FK3 ( Chain: A, B)
    B-Raf Kinase V600e Oncogenic Mutant In Complex With Plx3203
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.0e-203317View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-203317View alignment
    4R5Y ( Chain: A, B)
    The Complex Structure Of Braf V600e Kinase Domain With A Novel Braf Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.0e-203317View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-203317View alignment
    3HYH ( Chain: A, B)
    Crystal Structure Of The Protein Kinase Domain Of Yeast Amp-Activated Protein Kinase Snf1
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain A = 3.0e-203122View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-203122View alignment
    3DAE ( Chain: A, B)
    Crystal Structure Of Phosphorylated Snf1 Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain A = 3.0e-203122View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-203122View alignment
    3MN3 ( Chain: A)
    An Inhibited Conformation For The Protein Kinase Domain Of The Saccharomyces Cerevisiae Ampk Homolog Snf1
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae3.0e-203122View alignmentSCOP
    MMDB
    CATH
    2FH9 ( Chain: A)
    Structure And Dimerization Of The Kinase Domain From Yeast Snf1
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae3.0e-203122View alignmentSCOP
    MMDB
    CATH
    4CQG ( Chain: A)
    The Crystal Structure Of Mpk38 In Complex With Otssp167, An Orally-administrative Melk Selective Inhibitor
  • PDB_Info
  • PDB_Structure
  • Mus musculus3.0e-202721View alignmentSCOP
    MMDB
    CATH
    4BFM ( Chain: A)
    The Crystal Structure Of Mouse Pk38
  • PDB_Info
  • PDB_Structure
  • Mus musculus3.0e-202721View alignmentSCOP
    MMDB
    CATH
    3GU4 ( Chain: A)
    Crystal Structure Of Dapkq23v-Amppnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-202622View alignmentSCOP
    MMDB
    CATH
    3GU5 ( Chain: A)
    Crystal Structure Of Dapkq23v-Amppnp-Mg2+
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-202622View alignmentSCOP
    MMDB
    CATH
    3GU6 ( Chain: A)
    Crystal Structure Of Dapkq23v-Adp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-202622View alignmentSCOP
    MMDB
    CATH
    3GU7 ( Chain: A)
    Crystal Structure Of Dapkq23v-Adp-Mg2+
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.0e-202622View alignmentSCOP
    MMDB
    CATH
    1V0O ( Chain: A, B)
    Structure Of P. Falciparum Pfpk5-Indirubin-5-Sulphonate Ligand Complex
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparumChain A = 3.0e-203317View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-203317View alignment
    1V0B ( Chain: A, B)
    Crystal Structure Of The T198a Mutant Of Pfpk5
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparumChain A = 3.0e-203317View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-203317View alignment
    1OB3 ( Chain: A, B)
    Structure Of P. Falciparum Pfpk5
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparumChain A = 3.0e-203317View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.0e-203317View alignment
    3EHA ( Chain: A)
    Crystal Structure Of Death Associated Protein Kinase Complexed With Amppnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    4YO4 ( Chain: A)
    Crystal Structure Of Dapk1 Catalytic Domain In Complex With The Hinge Binding Fragment Phthalazine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    4YPD ( Chain: A)
    Crystal Structure Of Dapk1 Catalytic Domain In Complex With The Hinge Binding Fragment 4-methylpyridazine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    3DFC ( Chain: B)
    Crystal Structure Of A Glycine-rich Loop Mutant Of The Death Associated Protein Kinase Catalytic Domain With Amppnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    3DGK ( Chain: A)
    Crystal Structure Of A Glycine-rich Loop Mutant Of The Death Associated Protein Kinase Catalytic Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    3F5U ( Chain: A)
    Crystal Structure Of The Death Associated Protein Kinase In Complex With Amppnp And Mg2+
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    1JOW ( Chain: B)
    Crystal Structure Of A Complex Of Human Cdk6 And A Viral Cyclin
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    1XO2 ( Chain: B)
    Crystal Structure Of A Human Cyclin-Dependent Kinase 6 Complex With A Flavonol Inhibitor, Fisetin
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    2EUF ( Chain: B)
    X-Ray Structure Of Human Cdk6-Vcyclin In Complex With The Inhibitor Pd0332991
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    2F2C ( Chain: B)
    X-Ray Structure Of Human Cdk6-Vcyclinwith The Inhibitor Aminopurvalanol
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    1BI8 ( Chain: A, C)
    Mechanism Of G1 Cyclin Dependent Kinase Inhibition From The Structures Cdk6-P19ink4d Inhibitor Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.7e-203120View alignmentSCOP
    MMDB
    CATH
    Chain C = 3.7e-203120View alignment
    1BI7 ( Chain: A)
    Mechanism Of G1 Cyclin Dependent Kinase Inhibition From The Structure Of The Cdk6-P16ink4a Tumor Suppressor Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    1BLX ( Chain: A)
    P19ink4dCDK6 COMPLEX
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    1G3N ( Chain: A, E)
    Structure Of A P18(Ink4c)-Cdk6-K-Cyclin Ternary Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.7e-203120View alignmentSCOP
    MMDB
    CATH
    Chain E = 3.7e-203120View alignment
    4TTH ( Chain: B)
    Crystal Structure Of A Cdk6/vcyclin Complex With Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    3NUP ( Chain: A)
    Cdk6 (Monomeric) In Complex With Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    3NUX ( Chain: A)
    Cdk6 (Monomeric) In Complex With Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    4AUA ( Chain: A)
    Liganded X-ray Crystal Structure Of Cyclin Dependent Kinase 6 (cdk6)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    4EZ5 ( Chain: A)
    Cdk6 (monomeric) In Complex With Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    5L2I ( Chain: A)
    The X-ray Co-crystal Structure Of Human Cdk6 And Palbociclib.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    5L2S ( Chain: A)
    The X-ray Co-crystal Structure Of Human Cdk6 And Abemaciclib.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    5L2T ( Chain: A)
    The X-ray Co-crystal Structure Of Human Cdk6 And Ribociclib.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203120View alignmentSCOP
    MMDB
    CATH
    2HW6 ( Chain: A, B)
    Crystal Structure Of Mnk1 Catalytic Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.7e-202918View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.7e-202918View alignment
    3OG7 ( Chain: A, B)
    B-Raf Kinase V600e Oncogenic Mutant In Complex With Plx4032
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.7e-203317View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.7e-203317View alignment
    4TXC ( Chain: A)
    Crystal Structure Of Dapk1 Kinase Domain In Complex With A Small Molecule Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    4PF4 ( Chain: A)
    1.1a X-ray Structure Of The Apo Catalytic Domain Of Death-associated Protein Kinase 1, Aa 1-277
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    2YAK ( Chain: A)
    Structure Of Death-Associated Protein Kinase 1 (Dapk1) In Complex With A Ruthenium Octasporine Ligand (Osv)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    2Y4P ( Chain: A, B, C, D)
    Dimeric Structure Of Dapk-1 Catalytic Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.7e-202622View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.7e-202622View alignment
    Chain C = 3.7e-202622View alignment
    Chain D = 3.7e-202622View alignment
    4RLO ( Chain: A, B)
    Human P70s6k1 With Ruthenium-based Inhibitor Em5
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.7e-203018View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.7e-203018View alignment
    4RLP ( Chain: A)
    Human P70s6k1 With Ruthenium-based Inhibitor Fl772
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203018View alignmentSCOP
    MMDB
    CATH
    4L3J ( Chain: A)
    Crystal Structures Of Human P70s6k1 Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203018View alignmentSCOP
    MMDB
    CATH
    4L3L ( Chain: A)
    Crystal Structures Of Human P70s6k1 Kinase Domain (zinc Anomalous)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203018View alignmentSCOP
    MMDB
    CATH
    3A60 ( Chain: A, B)
    Crystal Structure Of Unphosphorylated P70s6k1 (Form I)
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.7e-203018View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.7e-203018View alignment
    3A61 ( Chain: A)
    Crystal Structure Of Unphosphorylated P70s6k1 (Form Ii)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-203018View alignmentSCOP
    MMDB
    CATH
    2W4J ( Chain: A)
    X-Ray Structure Of A Dap-Kinase 2-277
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    1WVW ( Chain: A)
    Crystal Structures Of Kinase Domain Of Dap Kinase In Complex With Small Molecular Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    1WVX ( Chain: A)
    Crystal Structures Of Kinase Domain Of Dap Kinase In Complex With Small Molecular Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    1WVY ( Chain: A)
    Crystal Structures Of Kinase Domain Of Dap Kinase In Complex With Small Molecular Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    3ZXT ( Chain: A, B, C, D)
    Dimeric Structure Of Dapk-1 Catalytic Domain In Complex With Amppcp-Mg
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.7e-202622View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.7e-202622View alignment
    Chain C = 3.7e-202622View alignment
    Chain D = 3.7e-202622View alignment
    1P4F ( Chain: A)
    Death Associated Protein Kinase Catalytic Domain With Bound Inhibitor Fragment
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    1IG1 ( Chain: A)
    1.8a X-Ray Structure Of Ternary Complex Of A Catalytic Domain Of Death-Associated Protein Kinase With Atp Analogue And Mn.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    1JKL ( Chain: A)
    1.6a X-Ray Structure Of Binary Complex Of A Catalytic Domain Of Death-Associated Protein Kinase With Atp Analogue
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    1JKS ( Chain: A)
    1.5a X-Ray Structure Of Apo Form Of A Catalytic Domain Of Death-Associated Protein Kinase
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    1JKT ( Chain: A, B)
    Tetragonal Crystal Form Of A Catalytic Domain Of Death-Associated Protein Kinase
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.7e-202622View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.7e-202622View alignment
    1JKK ( Chain: A)
    2.4a X-Ray Structure Of Ternary Complex Of A Catalytic Domain Of Death-Associated Protein Kinase With Atp Analogue And Mg.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    3F5G ( Chain: A)
    Crystal Structure Of Death Associated Protein Kinase In Complex With Adp And Mg2+
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    3EH9 ( Chain: A)
    Crystal Structure Of Death Associated Protein Kinase Complexed With Adp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.7e-202622View alignmentSCOP
    MMDB
    CATH
    3OHT ( Chain: A, B)
    Crystal Structure Of Salmo Salar P38alpha
  • PDB_Info
  • PDB_Structure
  • Salmo salarChain A = 4.0e-203025View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.0e-203025View alignment
    3RNY ( Chain: A, B)
    Crystal Structure Of Human Rsk1 C-Terminal Kinase Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.1e-202821View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.1e-202821View alignment
    2GU8 ( Chain: A)
    Discovery Of 2-pyrimidyl-5-amidothiophenes As Novel And Potent Inhibitors For Akt: Synthesis And Sar Studies
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.5e-203319View alignmentSCOP
    MMDB
    CATH
    5EAK ( Chain: B, A)
    Optimization Of Microtubule Affinity Regulating Kinase (mark) Inhibitors With Improved Physical Properties
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 4.9e-202822View alignmentSCOP
    MMDB
    CATH
    Chain A = 4.9e-202822View alignment
    1ZY5 ( Chain: B, A)
    Crystal Structure Of Eif2alpha Protein Kinase Gcn2: R794g Hyperactivating Mutant Complexed With Amppnp.
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain B = 4.9e-202818View alignmentSCOP
    MMDB
    CATH
    Chain A = 4.9e-202818View alignment
    1ZY4 ( Chain: A, B)
    Crystal Structure Of Eif2alpha Protein Kinase Gcn2: R794g Hyperactivating Mutant In Apo Form.
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain A = 4.9e-202818View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.9e-202818View alignment
    3HZT ( Chain: A)
    Crystal Structure Of Toxoplasma Gondii Cdpk3, Tgme49_105860
  • PDB_Info
  • PDB_Structure
  • Toxoplasma gondii ME495.7e-202917View alignmentSCOP
    MMDB
    CATH
    1ZMU ( Chain: B, A)
    Catalytic And Ubiqutin-Associated Domains Of Mark2PAR-1: Wild Type
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicusChain B = 6.3e-202824View alignmentSCOP
    MMDB
    CATH
    Chain A = 6.3e-202824View alignment
    2R0I ( Chain: B, A)
    Crystal Structure Of A Kinase Mark2PAR-1 Mutant
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicusChain B = 6.3e-202824View alignmentSCOP
    MMDB
    CATH
    Chain A = 6.3e-202824View alignment
    3KA0 ( Chain: A)
    Mk2 Complex With Inhibitor 6-(5-(2-Aminopyrimidin-4-Ylamino)-2- Hydroxyphenyl)-N-Methylbenzo[b]thiophene-2-Carboxamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens8.0e-202919View alignmentSCOP
    MMDB
    CATH
    3A62 ( Chain: A)
    Crystal Structure Of Phosphorylated P70s6k1
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.0e-193017View alignmentSCOP
    MMDB
    CATH
    4JVG ( Chain: C, A, B, D)
    B-raf Kinase In Complex With Birb796
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain C = 1.0e-193118View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.0e-193118View alignment
    Chain B = 1.0e-193118View alignment
    Chain D = 1.0e-193118View alignment
    3GUB ( Chain: A)
    Crystal Structure Of Dapkl93g Complexed With N6-(2- Phenylethyl)adenosine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.0e-192720View alignmentSCOP
    MMDB
    CATH
    3GU8 ( Chain: A)
    Crystal Structure Of Dapkl93g With N6-Cyclopentyladenosine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.0e-192720View alignmentSCOP
    MMDB
    CATH
    2YAC ( Chain: A)
    Crystal Structure Of Polo-Like Kinase 1 In Complex With Nms-P937
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.0e-192920View alignmentSCOP
    MMDB
    CATH
    4A4L ( Chain: A)
    Crystal Structure Of Polo-Like Kinase 1 In Complex With A 5-(2-Amino-Pyrimidin-4-Yl)-1h-Pyrrole Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.0e-192920View alignmentSCOP
    MMDB
    CATH
    4A4O ( Chain: A)
    Crystal Structure Of Polo-Like Kinase 1 In Complex With A 2- (2-Amino-Pyrimidin-4-Yl)-1,5,6,7-Tetrahydro-Pyrrolopyridin- 4-One Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.0e-192920View alignmentSCOP
    MMDB
    CATH
    3KB7 ( Chain: A)
    Crystal Structure Of Polo-Like Kinase 1 In Complex With A Pyrazoloquinazoline Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.0e-192920View alignmentSCOP
    MMDB
    CATH
    2V5Q ( Chain: A, B)
    Crystal Structure Of Wild-type Plk-1 Kinase Domain In Complex With A Selective Darpin
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.0e-192920View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.0e-192920View alignment
    1ZRZ ( Chain: A)
    Crystal Structure Of The Catalytic Domain Of Atypical Protein Kinase C-Iota
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.0e-192922View alignmentSCOP
    MMDB
    CATH
    1ZMV ( Chain: A, B)
    Catalytic And Ubiqutin-Associated Domains Of Mark2PAR-1: K82r Mutant
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicusChain A = 1.2e-192824View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.2e-192824View alignment
    3F69 ( Chain: B, A)
    Crystal Structure Of The Mycobacterium Tuberculosis Pknb Mutant Kinase Domain In Complex With Kt5720
  • PDB_Info
  • PDB_Structure
  • Mycobacterium tuberculosisChain B = 1.2e-193217View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.2e-193217View alignment
    4B6L ( Chain: A)
    Discovery Of Oral Polo-like Kinase (plk) Inhibitors With Enhanced Selectivity Profile Using Residue Targeted Drug Design
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.2e-192820View alignmentSCOP
    MMDB
    CATH
    2QR7 ( Chain: A)
    2.0a X-Ray Structure Of C-Terminal Kinase Domain Of P90 Ribosomal S6 Kinase 2: Se-Met Derivative
  • PDB_Info
  • PDB_Structure
  • Mus musculus1.6e-192720View alignmentSCOP
    MMDB
    CATH
    5ITA ( Chain: B, A)
    Crystal Structure Of Braf Kinase Domain Bound To Az-vem
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 1.7e-193218View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.7e-193218View alignment
    4WO5 ( Chain: A, B)
    Crystal Structure Of A Braf Kinase Domain Monomer
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-193218View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-193218View alignment
    3IEC ( Chain: A, B, C, D)
    Helicobacter Pylori Caga Inhibits Par1MARK FAMILY KINASES BY Mimicking Host Substrates
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-192725View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-192725View alignment
    Chain C = 1.7e-192725View alignment
    Chain D = 1.7e-192725View alignment
    2A2A ( Chain: A, B, C, D)
    High-resolution Crystallographic Analysis Of The Autoinhibited Conformation Of A Human Death-associated Protein Kinase
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-192622View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-192622View alignment
    Chain C = 1.7e-192622View alignment
    Chain D = 1.7e-192622View alignment
    2CKE ( Chain: A, B, C, D)
    Human Death-Associated Drp-1 Kinase In Complex With Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-192622View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-192622View alignment
    Chain C = 1.7e-192622View alignment
    Chain D = 1.7e-192622View alignment
    1WMK ( Chain: A, E, C, B, F, D, H, G)
    Human Death-Associated Kinase Drp-1, Mutant S308d D40
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-192522View alignmentSCOP
    MMDB
    CATH
    Chain E = 1.7e-192522View alignment
    Chain C = 1.7e-192522View alignment
    Chain B = 1.7e-192522View alignment
    Chain F = 1.7e-192522View alignment
    Chain D = 1.7e-192522View alignment
    Chain H = 1.7e-192522View alignment
    Chain G = 1.7e-192522View alignment
    2AC5 ( Chain: A)
    Structure Of Human Mnk2 Kinase Domain Mutant D228g
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-193018View alignmentSCOP
    MMDB
    CATH
    2HW7 ( Chain: A)
    Crystal Structure Of Mnk2-D228g In Complex With Staurosporine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-193018View alignmentSCOP
    MMDB
    CATH
    3C4C ( Chain: A, B)
    B-Raf Kinase In Complex With Plx4720
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-193218View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-193218View alignment
    5CSW ( Chain: A, B)
    B-raf In Complex With Dabrafenib
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.7e-193218View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.7e-193218View alignment
    5CSX ( Chain: A)
    Crystal Structure Of B-raf In Complex With Bi 882370
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-193218View alignmentSCOP
    MMDB
    CATH
    4XV9 ( Chain: A)
    B-raf Kinase Domain In Complex With Plx5568
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.7e-193218View alignmentSCOP
    MMDB
    CATH
    5ACB ( Chain: C, D)
    Crystal Structure Of The Human Cdk12-cyclink Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain C = 1.8e-193017View alignmentSCOP
    MMDB
    CATH
    Chain D = 1.8e-193017View alignment
    4CXA ( Chain: C, A)
    Crystal Structure Of The Human Cdk12-cyclin K Complex Bound To Amppnp
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain C = 1.8e-193017View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.8e-193017View alignment
    3J4Q ( Chain: D, E)
    Pseudo-atomic Model Of The Akap18-pka Complex In A Bent Conformation Derived From Electron Microscopy
  • PDB_Info
  • PDB_Structure
  • Mus musculusChain D = 1.8e-193320View alignmentSCOP
    MMDB
    CATH
    Chain E = 1.8e-193320View alignment
    3J4R ( Chain: E, D)
    Pseudo-atomic Model Of The Akap18-pka Complex In A Linear Conformation Derived From Electron Microscopy
  • PDB_Info
  • PDB_Structure
  • Mus musculusChain E = 1.8e-193320View alignmentSCOP
    MMDB
    CATH
    Chain D = 1.8e-193320View alignment
    3WF9 ( Chain: A)
    Crystal Structure Of S6k1 Kinase Domain In Complex With A Quinoline Derivative 1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl-2-methyl-1, 2,3,4-tetrahydroacridine-9-carboxylate
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.1e-193017View alignmentSCOP
    MMDB
    CATH
    3WF8 ( Chain: A)
    Crystal Structure Of S6k1 Kinase Domain In Complex With A Quinoline Derivative 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10- Tetrahydro-6h-cyclohepta[b]quinoline-11-carboxylate
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.1e-193017View alignmentSCOP
    MMDB
    CATH
    3WF7 ( Chain: A)
    Crystal Structure Of S6k1 Kinase Domain In Complex With A Purine Derivative 1-(9h-purin-6-yl)-n-[3-(trifluoromethyl)phenyl]piperidine- 4-carboxamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.1e-193017View alignmentSCOP
    MMDB
    CATH
    3WF5 ( Chain: A)
    Crystal Structure Of S6k1 Kinase Domain In Complex With A Pyrazolopyrimidine Derivative 4-[4-(1h-benzimidazol-2-yl)piperidin-1- Yl]-1h-pyrazolo[3,4-d]pyrimidine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.1e-193017View alignmentSCOP
    MMDB
    CATH
    3WE4 ( Chain: A)
    Crystal Structure Of S6k1 Kinase Domain In Complex With A Pyrimidine Derivative Pf-4708671 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1- Yl]methyl}-5-(trifluoromethyl)-1h-benzimidazole
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.1e-193017View alignmentSCOP
    MMDB
    CATH
    3WF6 ( Chain: A)
    Crystal Structure Of S6k1 Kinase Domain In Complex With A Pyrazolopyrimidine Derivative 4-[4-(1h-indol-3-yl)-3,6- Dihydropyridin-1(2h)-yl]-1h-pyrazolo[3,4-d]pyrimidine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.1e-193017View alignmentSCOP
    MMDB
    CATH
    4RZW ( Chain: B, A)
    Crystal Structure Of Braf (r509h) Kinase Domain Bound To Az628
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 2.1e-193217View alignmentSCOP
    MMDB
    CATH
    Chain A = 2.1e-193217View alignment
    4CT1 ( Chain: A)
    Human Pdk1-pkczeta Kinase Chimera In Complex With Allosteric Compound Ps315 Bound To The Pif-pocket
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.1e-193119View alignmentSCOP
    MMDB
    CATH
    4RZV ( Chain: B, A)
    Crystal Structure Of The Braf (r509h) Kinase Domain Monomer Bound To Vemurafenib
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 2.1e-193217View alignmentSCOP
    MMDB
    CATH
    Chain A = 2.1e-193217View alignment
    3F61 ( Chain: A)
    Crystal Structure Of M. Tuberculosis Pknb Leu33aspVAL222ASP DOUBLE MUTANT IN COMPLEX WITH ADP
  • PDB_Info
  • PDB_Structure
  • Mycobacterium tuberculosis2.1e-193118View alignmentSCOP
    MMDB
    CATH
    3ORT ( Chain: A)
    Mycobacterium Tuberculosis Pknb Kinase Domain L33d Mutant (Crystal Form 6)
  • PDB_Info
  • PDB_Structure
  • Mycobacterium tuberculosis H37Ra2.1e-193118View alignmentSCOP
    MMDB
    CATH
    3ORP ( Chain: A)
    Mycobacterium Tuberculosis Pknb Kinase Domain L33d Mutant (Crystal Form 5)
  • PDB_Info
  • PDB_Structure
  • Mycobacterium tuberculosis H37Ra2.1e-193118View alignmentSCOP
    MMDB
    CATH
    3ORO ( Chain: A)
    Mycobacterium Tuberculosis Pknb Kinase Domain L33d Mutant (Crystal Form 4)
  • PDB_Info
  • PDB_Structure
  • Mycobacterium tuberculosis H37Ra2.1e-193118View alignmentSCOP
    MMDB
    CATH
    3ORL ( Chain: A)
    Mycobacterium Tuberculosis Pknb Kinase Domain L33d Mutant (Crystal Form 3)
  • PDB_Info
  • PDB_Structure
  • Mycobacterium tuberculosis H37Ra2.1e-193118View alignmentSCOP
    MMDB
    CATH
    3ORK ( Chain: A)
    Mycobacterium Tuberculosis Pknb Kinase Domain L33d Mutant (Crystal Form 2)
  • PDB_Info
  • PDB_Structure
  • Mycobacterium tuberculosis H37Ra2.1e-193118View alignmentSCOP
    MMDB
    CATH
    3ORI ( Chain: D, C, B, A)
    Mycobacterium Tuberculosis Pknb Kinase Domain L33d Mutant (Crystal Form 1)
  • PDB_Info
  • PDB_Structure
  • Mycobacterium tuberculosis H37RaChain D = 2.1e-193118View alignmentSCOP
    MMDB
    CATH
    Chain C = 2.1e-193118View alignment
    Chain B = 2.1e-193118View alignment
    Chain A = 2.1e-193118View alignment
    4CT2 ( Chain: A)
    Human Pdk1-pkczeta Kinase Chimera
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.1e-193119View alignmentSCOP
    MMDB
    CATH
    4TYH ( Chain: A)
    Ternary Complex Of P38 And Mk2 With A P38 Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.3e-193019View alignmentSCOP
    MMDB
    CATH
    4RGJ ( Chain: A)
    Apo Crystal Structure Of Cdpk4 From Plasmodium Falciparum, Pf3d7_0717500
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparum2.4e-192820View alignmentSCOP
    MMDB
    CATH
    4DC2 ( Chain: A)
    Structure Of Pkc In Complex With A Substrate Peptide From Par-3
  • PDB_Info
  • PDB_Structure
  • Mus musculus2.6e-192722View alignmentSCOP
    MMDB
    CATH
    4QOX ( Chain: A)
    Crystal Structure Of Cdpk4 From Plasmodium Falciparum, Pf3d7_0717500
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparum 3D72.6e-192820View alignmentSCOP
    MMDB
    CATH
    4AW2 ( Chain: A)
    Crystal Structure Of Cdc42 Binding Protein Kinase Alpha (Mrck Alpha)
  • PDB_Info
  • PDB_Structure
  • Rattus norvegicus2.8e-193220View alignmentSCOP
    MMDB
    CATH
    4EQM ( Chain: C, B, D, E, F, A)
    Structural Analysis Of Staphylococcus Aureus SerineTHREONINE KINASE Pknb
  • PDB_Info
  • PDB_Structure
  • Staphylococcus aureus subsp. aureus N315Chain C = 2.9e-193022View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.9e-193022View alignment
    Chain D = 2.9e-193022View alignment
    Chain E = 2.9e-193022View alignment
    Chain F = 2.9e-193022View alignment
    Chain A = 2.9e-193022View alignment
    3PWY ( Chain: A)
    Crystal Structure Of An Extender (Spd28345)-Modified Human Pdk1 Complex 2
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.9e-193020View alignmentSCOP
    MMDB
    CATH
    4OW8 ( Chain: A)
    Crystal Structure Of Kinase Domain Of Pkna From Mtb
  • PDB_Info
  • PDB_Structure
  • Mycobacterium tuberculosis2.9e-193120View alignmentSCOP
    MMDB
    CATH
    2OZA ( Chain: A)
    Structure Of P38alpha Complex
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.4e-193019View alignmentSCOP
    MMDB
    CATH
    4DFY ( Chain: A, E)
    Crystal Structure Of R194a Mutant Of Camp-Dependent Protein Kinase With Unphosphorylated Activation Loop
  • PDB_Info
  • PDB_Structure
  • Mus musculusChain A = 3.5e-193320View alignmentSCOP
    MMDB
    CATH
    Chain E = 3.5e-193320View alignment
    4WNO ( Chain: A)
    Structure Of Ulk1 Bound To An Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.6e-193317View alignmentSCOP
    MMDB
    CATH
    4WNP ( Chain: A, B, C, D)
    Structure Of Ulk1 Bound To A Potent Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.6e-193317View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.6e-193317View alignment
    Chain C = 3.6e-193317View alignment
    Chain D = 3.6e-193317View alignment
    5CI7 ( Chain: A)
    Structure Of Ulk1 Bound To A Selective Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.6e-193317View alignmentSCOP
    MMDB
    CATH
    3D5U ( Chain: A)
    Crystal Structure Of A Wildtype Polo-Like Kinase 1 (Plk1) Catalytic Domain.
  • PDB_Info
  • PDB_Structure
  • Danio rerio3.6e-192924View alignmentSCOP
    MMDB
    CATH
    4J52 ( Chain: A)
    Crystal Structure Of Plk1 In Complex With A Pyrimidodiazepinone Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.6e-192821View alignmentSCOP
    MMDB
    CATH
    4J53 ( Chain: A)
    Crystal Structure Of Plk1 In Complex With Tak-960
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.6e-192821View alignmentSCOP
    MMDB
    CATH
    2RKU ( Chain: A)
    Structure Of Plk1 In Complex With Bi2536
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.6e-192821View alignmentSCOP
    MMDB
    CATH
    3C0I ( Chain: A)
    Cask Cam-Kinase Domain- 3'-Amp Complex, P212121 Form
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.6e-192817View alignmentSCOP
    MMDB
    CATH
    3C0H ( Chain: B, A)
    Cask Cam-Kinase Domain- Amppnp Complex, P1 Form
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 3.6e-192817View alignmentSCOP
    MMDB
    CATH
    Chain A = 3.6e-192817View alignment
    3C0G ( Chain: A, B)
    Cask Cam-kinase Domain- 3'-amp Complex, P1 Form
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.6e-192817View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.6e-192817View alignment
    3Q5I ( Chain: A)
    Crystal Structure Of Pbanka_031420
  • PDB_Info
  • PDB_Structure
  • Plasmodium berghei3.6e-192918View alignmentSCOP
    MMDB
    CATH
    3PPZ ( Chain: A, B)
    Crystal Structure Of Ctr1 Kinase Domain In Complex With Staurosporine
  • PDB_Info
  • PDB_Structure
  • Arabidopsis thalianaChain A = 4.6e-192922View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.6e-192922View alignment

    Last updated on 2016-09-15