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PDB Homolog: HSC82/YMR186W Help



This page presents information for the proteins of known structure with sequence similarity to the Saccharomyces cerevisiae protein HSC82/YMR186W. The analysis was performed by comparing yeast protein sequences against protein sequences in The RCSB Protein Databank (PDB) using WU-BLAST.
 
Last updated on 2014-06-05

273 PDB homolog(s) found for yeast gene HSC82/YMR186W

HSC82/YMR186W links
  • Locus Info
  • PDB protein structure(s) homologous to HSC82Homolog Source (per PDB)Protein Alignment: HSC82 vs. HomologExternal Links
    P-Value%Identical%SimilarAlignment
    2CG9 ( Chain: B, A)
    Crystal Structure Of An Hsp90-Sba1 Closed Chaperone Complex
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain B = 9.9e-262972View alignmentSCOP
    MMDB
    CATH
    Chain A = 9.9e-262972View alignment
    2CGE ( Chain: A, D, B)
    Crystal Structure Of An Hsp90-Sba1 Closed Chaperone Complex
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain A = 1.6e-209991View alignmentSCOP
    MMDB
    CATH
    Chain D = 1.6e-209991View alignment
    Chain B = 1.6e-209991View alignment
    2O1V ( Chain: A, B)
    Structure Of Full Length Grp94 With Adp Bound
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain A = 4.8e-1504618View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.8e-1504618View alignment
    2O1U ( Chain: B, A)
    Structure Of Full Length Grp94 With Amp-Pnp Bound
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain B = 4.8e-1504618View alignmentSCOP
    MMDB
    CATH
    Chain A = 4.8e-1504618View alignment
    1HK7 ( Chain: A, B)
    Middle Domain Of Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain A = 4.8e-150991View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.8e-150991View alignment
    3HJC ( Chain: A)
    Crystal Structure Of The Carboxy-Terminal Domain Of Hsp90 From Leishmania Major, Lmjf33.0312
  • PDB_Info
  • PDB_Structure
  • Leishmania major4.3e-1426216View alignmentSCOP
    MMDB
    CATH
    3Q6M ( Chain: C, B, A)
    Crystal Structure Of Human Mc-hsp90 In C2221 Space Group
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain C = 9.9e-1416117View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.9e-1416117View alignment
    Chain A = 9.9e-1416117View alignment
    3Q6N ( Chain: A, F, E, D, C, B)
    Crystal Structure Of Human Mc-hsp90 In P21 Space Group
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 9.9e-1416117View alignmentSCOP
    MMDB
    CATH
    Chain F = 9.9e-1416117View alignment
    Chain E = 9.9e-1416117View alignment
    Chain D = 9.9e-1416117View alignment
    Chain C = 9.9e-1416117View alignment
    Chain B = 9.9e-1416117View alignment
    1USV ( Chain: E, C, A, G)
    The Structure Of The Complex Between Aha1 And Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain E = 5.3e-135991View alignmentSCOP
    MMDB
    CATH
    Chain C = 5.3e-135991View alignment
    Chain A = 5.3e-135991View alignment
    Chain G = 5.3e-135991View alignment
    1USU ( Chain: A)
    The Structure Of The Complex Between Aha1 And Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae3.8e-134991View alignmentSCOP
    MMDB
    CATH
    2IOP ( Chain: D, A, B, C)
    Crystal Structure Of Full-Length Htpg, The Escherichia Coli Hsp90, Bound To Adp
  • PDB_Info
  • PDB_Structure
  • Escherichia coliChain D = 1.2e-1143921View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.2e-1143921View alignment
    Chain B = 1.2e-1143921View alignment
    Chain C = 1.2e-1143921View alignment
    2IOQ ( Chain: A, B)
    Crystal Structure Of Full-Length Htpg, The Escherichia Coli Hsp90
  • PDB_Info
  • PDB_Structure
  • Escherichia coliChain A = 1.2e-1143921View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.2e-1143921View alignment
    2O1W ( Chain: E, A, B, C, D)
    Structure Of N-Terminal Plus Middle Domains (N+m) Of Grp94
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain E = 4.6e-1134617View alignmentSCOP
    MMDB
    CATH
    Chain A = 4.6e-1134617View alignment
    Chain B = 4.6e-1134617View alignment
    Chain C = 4.6e-1134617View alignment
    Chain D = 4.6e-1134617View alignment
    1Y4S ( Chain: B, A)
    Conformation Rearrangement Of Heat Shock Protein 90 Upon Adp Binding
  • PDB_Info
  • PDB_Structure
  • Escherichia coliChain B = 1.5e-1094121View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.5e-1094121View alignment
    4ASB ( Chain: A)
    The Structure Of Modified Benzoquinone Ansamycins Bound To Yeast N-terminal Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.6e-108964View alignmentSCOP
    MMDB
    CATH
    4ASA ( Chain: A)
    The Structure Of Modified Benzoquinone Ansamycins Bound To Yeast N-terminal Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.6e-108964View alignmentSCOP
    MMDB
    CATH
    4AS9 ( Chain: A)
    The Structure Of Modified Benzoquinone Ansamycins Bound To Yeast N-terminal Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.6e-108964View alignmentSCOP
    MMDB
    CATH
    1AH6 ( Chain: A)
    Structure Of The Tetragonal Form Of The N-Terminal Domain Of The Yeast Hsp90 Chaperone
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.6e-108964View alignmentSCOP
    MMDB
    CATH
    1AH8 ( Chain: B, A)
    Structure Of The Orthorhombic Form Of The N-Terminal Domain Of The Yeast Hsp90 Chaperone
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain B = 5.6e-108964View alignmentSCOP
    MMDB
    CATH
    Chain A = 5.6e-108964View alignment
    1A4H ( Chain: A)
    Structure Of The N-Terminal Domain Of The Yeast Hsp90 Chaperone In Complex With Geldanamycin
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.6e-108964View alignmentSCOP
    MMDB
    CATH
    2FXS ( Chain: A)
    Yeast Hsp82 In Complex With The Novel Hsp90 Inhibitor Radamide
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.6e-108964View alignmentSCOP
    MMDB
    CATH
    1ZWH ( Chain: A)
    Yeast Hsp82 In Complex With The Novel Hsp90 Inhibitor Radester Amine
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.6e-108964View alignmentSCOP
    MMDB
    CATH
    1ZW9 ( Chain: A)
    Yeast Hsp82 In Complex With The Novel Hsp90 Inhibitor 8-(6-Bromo- Benzo[1,3]dioxol-5-Ylsulfanyl)-9-(3-Isopropylamino-Propyl)-Adenine
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.6e-108964View alignmentSCOP
    MMDB
    CATH
    4ASF ( Chain: A)
    The Structure Of Modified Benzoquinone Ansamycins Bound To Yeast N-terminal Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.6e-108964View alignmentSCOP
    MMDB
    CATH
    4ASG ( Chain: A)
    The Structure Of Modified Benzoquinone Ansamycins Bound To Yeast N-terminal Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.6e-108964View alignmentSCOP
    MMDB
    CATH
    2WEP ( Chain: A)
    Yeast Hsp90 N-Terminal Domain Li-Iv Mutant With Adp
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.2e-107955View alignmentSCOP
    MMDB
    CATH
    2WEQ ( Chain: A)
    Yeast Hsp90 N-Terminal Domain Li-Iv Mutant With Geldanamycin
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.2e-107955View alignmentSCOP
    MMDB
    CATH
    2WER ( Chain: A, B)
    Yeast Hsp90 N-Terminal Domain Li-Iv Mutant With Radicicol
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain A = 1.2e-107955View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.2e-107955View alignment
    2BRE ( Chain: A, B)
    Structure Of A Hsp90 Inhibitor Bound To The N-Terminus Of Yeast Hsp90.
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain A = 3.2e-107964View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.2e-107964View alignment
    2VWC ( Chain: A)
    Structure Of The Hsp90 Inhibitor Macbecin Bound To The N- Terminus Of Yeast Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae3.2e-107964View alignmentSCOP
    MMDB
    CATH
    2YGF ( Chain: A)
    L89v, L93i And V136m Mutant Of N-term Hsp90 Complexed With Geldanamycin
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae4.0e-107955View alignmentSCOP
    MMDB
    CATH
    3C0E ( Chain: A)
    Yeast Hsp82 N-Terminal Domain: Effects Of Mutants 98-99 Ks- Aa
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.1e-107954View alignmentSCOP
    MMDB
    CATH
    3C11 ( Chain: A)
    Yeast Hsp82 N-Terminal Domain-Geldanamycin Complex: Effects Of Mutants 98-99 Ks-Aa
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae5.1e-107954View alignmentSCOP
    MMDB
    CATH
    2YGE ( Chain: A)
    E88g-n92l Mutant Of N-term Hsp90 Complexed With Geldanamycin
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.3e-106954View alignmentSCOP
    MMDB
    CATH
    2YGA ( Chain: A)
    E88g-n92l Mutant Of N-term Hsp90 Complexed With Geldanamycin
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae9.6e-106954View alignmentSCOP
    MMDB
    CATH
    2O1T ( Chain: B, C, D, J, F, G, H, I, A, E)
    Structure Of Middle Plus C-Terminal Domains (M+c) Of Grp94
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain B = 1.2e-1054819View alignmentSCOP
    MMDB
    CATH
    Chain C = 1.2e-1054819View alignment
    Chain D = 1.2e-1054819View alignment
    Chain J = 1.2e-1054819View alignment
    Chain F = 1.2e-1054819View alignment
    Chain G = 1.2e-1054819View alignment
    Chain H = 1.2e-1054819View alignment
    Chain I = 1.2e-1054819View alignment
    Chain A = 1.2e-1054819View alignment
    Chain E = 1.2e-1054819View alignment
    1BGQ ( Chain: A)
    Radicicol Bound To The Atp Binding Site Of The N-Terminal Domain Of The Yeast Hsp90 Chaperone
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    1US7 ( Chain: A)
    Complex Of Hsp90 And P50
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    2BRC ( Chain: A)
    Structure Of A Hsp90 Inhibitor Bound To The N-Terminus Of Yeast Hsp90.
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    2IWS ( Chain: A)
    Radicicol Analogues Bound To The Atp Site Of Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    2IWU ( Chain: A)
    Analogues Of Radicicol Bound To The Atp-Binding Site Of Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    2IWX ( Chain: A)
    Analogues Of Radicicol Bound To The Atp-Binding Site Of Hsp90.
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    1AMW ( Chain: A)
    Adp Binding Site In The Hsp90 Molecular Chaperone
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    2VW5 ( Chain: A, B, C, D)
    Structure Of The Hsp90 Inhibitor 7-O-Carbamoylpremacbecin Bound To The N- Terminus Of Yeast Hsp90
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain A = 1.4e-104964View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.4e-104964View alignment
    Chain C = 1.4e-104964View alignment
    Chain D = 1.4e-104964View alignment
    2XD6 ( Chain: A)
    Hsp90 Complexed With A Resorcylic Acid Macrolactone.
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    2XX4 ( Chain: A)
    Macrolactone Inhibitor Bound To Hsp90 N-Term
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    2XX5 ( Chain: A)
    Macrolactone Inhibitor Bound To Hsp90 N-Term
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    4CE1 ( Chain: A)
    Hsp90 N-terminal Domain Bound To Macrolactam Analogues Of Radicicol.
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    4CE2 ( Chain: A)
    Hsp90 N-terminal Domain Bound To Macrolactam Analogues Of Radicicol.
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    4CE3 ( Chain: A)
    Hsp90 N-terminal Domain Bound To Macrolactam Analogues Of Radicicol
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae1.4e-104964View alignmentSCOP
    MMDB
    CATH
    2CGF ( Chain: A)
    A Radicicol Analogue Bound To The Atp Binding Site Of The N- Terminal Domain Of The Yeast Hsp90 Chaperone
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae2.9e-104964View alignmentSCOP
    MMDB
    CATH
    2XX2 ( Chain: B, C, D, A)
    Macrolactone Inhibitor Bound To Hsp90 N-Term
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain B = 4.8e-104964View alignmentSCOP
    MMDB
    CATH
    Chain C = 4.8e-104964View alignment
    Chain D = 4.8e-104964View alignment
    Chain A = 4.8e-104964View alignment
    1AM1 ( Chain: A)
    Atp Binding Site In The Hsp90 Molecular Chaperone
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiae4.8e-104964View alignmentSCOP
    MMDB
    CATH
    3PRY ( Chain: A, B, C)
    Crystal Structure Of The Middle Domain Of Human Hsp90-Beta Refined At 2.3 A Resolution
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 4.1e-986819View alignmentSCOP
    MMDB
    CATH
    Chain B = 4.1e-986819View alignment
    Chain C = 4.1e-986819View alignment
    2AKP ( Chain: A, B)
    Hsp90 Delta24-n210 Mutant
  • PDB_Info
  • PDB_Structure
  • Saccharomyces cerevisiaeChain A = 8.4e-91964View alignmentSCOP
    MMDB
    CATH
    Chain B = 8.4e-91964View alignment
    4IVG ( Chain: A)
    Crystal Structure Of Mitochondrial Hsp90 (trap1) Ntd-middle Domain Dimer With Amppnp
  • PDB_Info
  • PDB_Structure
  • Danio rerio1.3e-833123View alignmentSCOP
    MMDB
    CATH
    4IPE ( Chain: B, A)
    Crystal Structure Of Mitochondrial Hsp90 (trap1) With Amppnp
  • PDB_Info
  • PDB_Structure
  • Danio rerioChain B = 1.6e-833123View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.6e-833123View alignment
    4IYN ( Chain: A, B)
    Structure Of Mitochondrial Hsp90 (trap1) With Adp-alf4-
  • PDB_Info
  • PDB_Structure
  • Danio rerioChain A = 1.6e-833123View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-833123View alignment
    4J0B ( Chain: A, B)
    Structure Of Mitochondrial Hsp90 (trap1) With Adp-bef3
  • PDB_Info
  • PDB_Structure
  • Danio rerioChain A = 1.6e-833123View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-833123View alignment
    3K60 ( Chain: A, B)
    Crystal Structure Of N-Terminal Domain Of Plasmodium Falciparum Hsp90 (Pf07_0029) Bound To Adp
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparum 3D7Chain A = 6.3e-777114View alignmentSCOP
    MMDB
    CATH
    Chain B = 6.3e-777114View alignment
    4GQT ( Chain: A, B)
    N-Terminal Domain Of C. Elegans Hsp90
  • PDB_Info
  • PDB_Structure
  • Caenorhabditis elegansChain A = 1.3e-767015View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.3e-767015View alignment
    2FWY ( Chain: A)
    Structure Of Human Hsp90-Alpha Bound To The Potent Water Soluble Inhibitor Pu-H64
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2FWZ ( Chain: A)
    Structure Of Human Hsp90-alpha Bound To The Potent Water Soluble Inhibitor Pu-h71
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2H55 ( Chain: A)
    Structure Of Human Hsp90-Alpha Bound To The Potent Water Soluble Inhibitor Pu-Dz8
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3O0I ( Chain: A)
    Structure Of The Human Hsp90-alpha N-domain Bound To The Hsp90 Inhibitor Pu-h54
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3FT5 ( Chain: A)
    Structure Of Hsp90 Bound With A Novel Fragment
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3FT8 ( Chain: A)
    Structure Of Hsp90 Bound With A Noval Fragment.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3HYY ( Chain: A)
    Crystal Structure Of Hsp90 With Fragment 37-D04
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3HYZ ( Chain: A, B)
    Crystal Structure Of Hsp90 With Fragment 42-C03
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    3HZ1 ( Chain: A)
    Crystal Structure Of Hsp90 With Fragments 37-D04 And 42-C03
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3HZ5 ( Chain: A)
    Crystal Structure Of Hsp90 With Fragment Z064
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2XAB ( Chain: A, B)
    Structure Of Hsp90 With An Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    2XJX ( Chain: A)
    Structure Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2XDK ( Chain: A)
    Structure Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2XDL ( Chain: A)
    Structure Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2XDS ( Chain: A)
    Structure Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2XDX ( Chain: A)
    Structre Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2XHR ( Chain: A)
    Structure Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2XHT ( Chain: A)
    Structure Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2XK2 ( Chain: A)
    Structure Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4JQL ( Chain: A)
    Synthesis Of Benzoquinone-ansamycin-inspired Macrocyclic Lactams From Shikimic Acid
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3INW ( Chain: A)
    Hsp90 N-Terminal Domain With Pochoxime A
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3INX ( Chain: A)
    Hsp90 N-Terminal Domain With Pochoxime B
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3R4M ( Chain: A)
    Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4- Fluoro-1h-Pyrazol-1-Yl)ethoxy]-6-Methylphenyl}-N-(2,2- Difluoropropyl)-5,7-Dihydro-6h-Pyrrolo[3,4-D]pyrimidine-6-Carboxamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3T0H ( Chain: A)
    Structure Insights Into Mechanisms Of Atp Hydrolysis And The Activation Of Human Hsp90
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3T0Z ( Chain: A)
    Hsp90 N-Terminal Domain Bound To Atp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3T10 ( Chain: A)
    Hsp90 N-Terminal Domain Bound To Acp
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3T1K ( Chain: A, B)
    Hsp90 N-Terminal Domain Bound To Anp
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    3T2S ( Chain: A, B)
    Hsp90 N-Terminal Domain Bound To Ags
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    4HY6 ( Chain: A)
    Crystal Structure Of The Human Hsp90-alpha N-domain Bound To The Hsp90 Inhibitor Fj1
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YE2 ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YE3 ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YE4 ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YE5 ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YE6 ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YE9 ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YEA ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YEB ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YEC ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YED ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YEF ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YEG ( Chain: A, B)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    2YEH ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YE7 ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YE8 ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YEI ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2YEJ ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3B24 ( Chain: A, B)
    Hsp90 Alpha N-terminal Domain In Complex With An Aminotriazine Fragment Molecule
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    3B25 ( Chain: A)
    Hsp90 Alpha N-terminal Domain In Complex With An Inhibitor Ch4675194
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3B26 ( Chain: A, B)
    Hsp90 Alpha N-terminal Domain In Complex With An Inhibitor Ro1127850
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    3B27 ( Chain: A)
    Hsp90 Alpha N-terminal Domain In Complex With An Inhibitor Ro4919127
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3B28 ( Chain: A, B)
    Hsp90 Alpha N-terminal Domain In Complex With An Inhibitor Ch5015765
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    3VHA ( Chain: A)
    Hsp90 Alpha N-Terminal Domain In Complex With A Macrocyclic Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3VHC ( Chain: A)
    Hsp90 Alpha N-Terminal Domain In Complex With A Macrocyclic Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3VHD ( Chain: A, B)
    Hsp90 Alpha N-Terminal Domain In Complex With A Macrocyclic Inhibitor, Ch5164840
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    3WHA ( Chain: A, B)
    Hsp90 Alpha N-terminal Domain In Complex With A Tricyclic Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    4EGH ( Chain: A)
    Hsp90-Alpha Atpase Domain In Complex With (4-Hydroxyphenyl)morpholin- 4-Yl Methanone
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4EGI ( Chain: A)
    Hsp90-Alpha Atpase Domain In Complex With 2-Amino-4-Ethylthio-6- Methyl-1,3,5-Triazine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4EGK ( Chain: A)
    Human Hsp90-Alpha Atpase Domain Bound To Radicicol
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4EEH ( Chain: A)
    Hsp90 Alpha N-Terminal Domain In Complex With An Inhibitor 3-(4- Hydroxy-Phenyl)-1h-Indazol-6-Ol
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4EFT ( Chain: A)
    Hsp90 Alpha N-Terminal Domain In Complex With An Inhibitor 3- Cyclohexyl-2-(6-Hydroxy-1h-Indazol-3-Yl)-Propionitrile
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4EFU ( Chain: A)
    Hsp90 Alpha N-Terminal Domain In Complex With An Inhibitor 6-Hydroxy- 3-(3-Methyl-Benzyl)-1h-Indazole-5-Carboxylic Acid Benzyl-Methyl-Amide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3QDD ( Chain: A)
    Hsp90a N-Terminal Domain In Complex With Biib021
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4AWO ( Chain: A, B)
    Complex Of Hsp90 Atpase Domain With Tropane Derived Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    4AWP ( Chain: A, B)
    Complex Of Hsp90 Atpase Domain With Tropane Derived Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    4AWQ ( Chain: A, B)
    Complex Of Hsp90 Atpase Domain With Tropane Derived Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    1UY6 ( Chain: A)
    Human Hsp90-Alpha With 9-Butyl-8-(3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UY7 ( Chain: A)
    Human Hsp90-alpha With 9-butyl-8-(4-methoxy-benzyl)-9h-purin-6-ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UY8 ( Chain: A)
    Human Hsp90-Alpha With 9-Butyl-8-(3-Trimethoxy-Benzyl)-9h-Purin-6ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UY9 ( Chain: A)
    Human Hsp90-Alpha With 8-Benzo[1,3]dioxol-,5-Ylmethyl-9-Butyl-9h-Purin-6-Ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UYC ( Chain: A)
    Human Hsp90-Alpha With 9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UYD ( Chain: A)
    Human Hsp90-Alpha With 9-Butyl-8- (2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UYE ( Chain: A)
    Human Hsp90-Alpha With 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl) -9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UYF ( Chain: A)
    Human Hsp90-Alpha With 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl) -2-Fluoro-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UYG ( Chain: A)
    Human Hsp90-Alpha With 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UYH ( Chain: A)
    Human Hsp90-Alpha With 9-Butyl-8- (2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UYK ( Chain: A)
    Human Hsp90-Alpha With 8-Benzo[1,3]dioxol-,5-Ylmethyl-9-But Yl-2-Fluoro-9h-Purin-6-Ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UYL ( Chain: A)
    Structure-Activity Relationships In Purine-Based Inhibitor Binding To Hsp90 Isoforms
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2UWD ( Chain: A)
    Inhibition Of The Hsp90 Molecular Chaperone In Vitro And In Vivo By Novel, Synthetic, Potent Resorcinylic Pyrazole, Isoxazole Amide Analogs
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2VCI ( Chain: A)
    4,5 Diaryl Isoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents For The Treatment Of Cancer
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2VCJ ( Chain: A)
    4,5 Diaryl Isoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents For The Treatment Of Cancer
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2WI1 ( Chain: A)
    Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2WI2 ( Chain: A, B)
    Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    2WI3 ( Chain: A)
    Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2WI4 ( Chain: A)
    Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2WI5 ( Chain: A)
    Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2WI6 ( Chain: A)
    Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2WI7 ( Chain: A)
    Orally Active 2-Amino Thienopyrimidine Inhibitors Of The Hsp90 Chaperone
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4FCP ( Chain: A, B)
    Targetting Conserved Water Molecules: Design Of 4-Aryl-5-Cyanopyrrolo [2,3-D] Pyrimidine Hsp90 Inhibitors Using Fragment-Based Screening And Structure-Based Optimization
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    4FCQ ( Chain: A)
    Targeting Conserved Water Molecules: Design Of 4-Aryl-5- Cyanopyrrolo[2,3-D]pyrimidine Hsp90 Inhibitors Using Fragment-Based Screening And Structure-Based Optimization
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4FCR ( Chain: A)
    Targeting Conserved Water Molecules: Design Of 4-Aryl-5- Cyanopyrrolo[2,3-D]pyrimidine Hsp90 Inhibitors Using Fragment-Based Screening And Structure-Based Optimization
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    1UYI ( Chain: A)
    Human Hsp90-Alpha With 8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9- Pent-9h-Purin-6-Ylamine
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2BSM ( Chain: A)
    Novel, Potent Small Molecule Inhibitors Of The Molecular Chaperone Hsp90 Discovered Through Structure-Based Design
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2BT0 ( Chain: A, B)
    Novel, Potent Small Molecule Inhibitors Of The Molecular Chaperone Hsp90 Discovered Through Structure-Based Design
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    2BYH ( Chain: A)
    3-(5-Chloro-2,4-Dihydroxyphenyl)-Pyrazole-4-Carboxamides As Inhibitors Of The Hsp90 Molecular Chaperone
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2BYI ( Chain: A)
    3-(5-Chloro-2,4-Dihydroxyphenyl)-Pyrazole-4-Carboxamides As Inhibitors Of The Hsp90 Molecular Chaperone
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2BZ5 ( Chain: A, B)
    Structure-Based Discovery Of A New Class Of Hsp90 Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    4B7P ( Chain: A)
    Structure Of Hsp90 With Nms-e973 Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4BQG ( Chain: A)
    Structure Of Hsp90 With An Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4BQJ ( Chain: A)
    Structure Of Hsp90 With An Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4NH7 ( Chain: A, B)
    Correlation Between Chemotype-dependent Binding Conformations Of Hsp90 Alpha/beta And Isoform Selectivity
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.6e-766914View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766914View alignment
    4NH8 ( Chain: A)
    Correlation Between Chemotype-dependent Binding Conformations Of Hsp90 Alpha/beta And Isoform Selectivity
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4O05 ( Chain: A)
    Identification Of Novel Hsp90/isoform Selective Inhibitors Using Structure-based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington's Disease
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4O07 ( Chain: A)
    Identification Of Novel Hsp90/isoform Selective Inhibitors Using Structure-based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington's Disease
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4O09 ( Chain: A)
    Identification Of Novel Hsp90 / Isoform Selective Inhibitors Using Structure-based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington S Disease
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    4O0B ( Chain: A)
    Identification Of Novel Hsp90/isoform Selective Inhibitors Using Structure-based Drug Design. Demonstration Of Potential Utility In Treating Cns Disorders Such As Huntington's Disease
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3BM9 ( Chain: A)
    Discovery Of Benzisoxazoles As Potent Inhibitors Of Chaperone Hsp90
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3BMY ( Chain: A)
    Discovery Of Benzisoxazoles As Potent Inhibitors Of Chaperone Hsp90
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3QTF ( Chain: A)
    Design And Sar Of Macrocyclic Hsp90 Inhibitors With Increased Metabolic Stability And Potent Cell-Proliferation Activity
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3R91 ( Chain: A)
    Macrocyclic Lactams As Potent Hsp90 Inhibitors With Excellent Tumor Exposure And Extended Biomarker Activity.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3R92 ( Chain: A)
    Discovery Of A Macrocyclic O-Aminobenzamide Hsp90 Inhibitor With Heterocyclic Tether That Shows Extended Biomarker Activity And In Vivo Efficacy In A Mouse Xenograft Model.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    3RKZ ( Chain: A)
    Discovery Of A Stable Macrocyclic O-Aminobenzamide Hsp90 Inhibitor Capable Of Significantly Decreasing Tumor Volume In A Mouse Xenograft Model
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2JKI ( Chain: A, B, C)
    Complex Of Hsp90 N-terminal And Sgt1 Cs Domain
  • PDB_Info
  • PDB_Structure
  • Hordeum vulgareChain A = 1.6e-766915View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.6e-766915View alignment
    Chain C = 1.6e-766915View alignment
    3K97 ( Chain: A)
    Hsp90 N-Terminal Domain In Complex With 4-Chloro-6-{[(2r)-2- (2-Methylphenyl)pyrrolidin-1-Yl]carbonyl}benzene-1,3-Diol
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.6e-766914View alignmentSCOP
    MMDB
    CATH
    2CCS ( Chain: A)
    Human Hsp90 With 4-Chloro-6-(4-Piperazin-1-Yl-1h-Pyrazol-3- Yl)-Benzene-1,2-Diol
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    2CCT ( Chain: A)
    Human Hsp90 With 5-(5-Chloro-2,4-Dihydroxy-Phenyl)-4- Piperazin-1-Yl-2h-Pyrazole-3-Carboxylic Acid Ethylamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    2CCU ( Chain: A)
    Human Hsp90 With 4-Chloro-6-(4-(4-(4-Methanesulphonyl- Benzyl)-Pierazin-1-Yl)-1h-Pyrazol-3-Yl)-Benzene-1,3-Diol
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    2XJG ( Chain: A)
    Structure Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    2XHX ( Chain: A)
    Structure Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    1YC4 ( Chain: A)
    Crystal Structure Of Human Hsp90alpha Complexed With Dihydroxyphenylpyrazoles
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    1YER ( Chain: A)
    Human Hsp90 Geldanamycin-Binding Domain, "closed" Conformation
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    1YES ( Chain: A)
    Human Hsp90 Geldanamycin-Binding Domain, "open" Conformation
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    1YET ( Chain: A)
    Geldanamycin Bound To The Hsp90 Geldanamycin-Binding Domain
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    1YC1 ( Chain: A)
    Crystal Structures Of Human Hsp90alpha Complexed With Dihydroxyphenylpyrazoles
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    1YC3 ( Chain: A)
    Crystal Structure Of Human Hsp90alpha Complexed With Dihydroxyphenylpyrazoles
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    1BYQ ( Chain: A)
    Hsp90 N-Terminal Domain Bound To Adp-Mg
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.2e-766914View alignmentSCOP
    MMDB
    CATH
    3NMQ ( Chain: A)
    Hsp90b N-Terminal Domain In Complex With Ec44, A Pyrrolo-Pyrimidine Methoxypyridine Inhibitor
  • PDB_Info
  • PDB_Structure
  • Homo sapiens2.7e-767114View alignmentSCOP
    MMDB
    CATH
    3D0B ( Chain: A)
    Crystal Structure Of Benzamide Tetrahydro-4h-Carbazol-4-One Bound To Hsp90
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.5e-767015View alignmentSCOP
    MMDB
    CATH
    3MNR ( Chain: P)
    Crystal Structure Of Benzamide Snx-1321 Bound To Hsp90
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.5e-767015View alignmentSCOP
    MMDB
    CATH
    2YEE ( Chain: A)
    Hsp90 Inhibitors And Drugs From Fragment And Virtual Screening
  • PDB_Info
  • PDB_Structure
  • Homo sapiens5.7e-766914View alignmentSCOP
    MMDB
    CATH
    2XJJ ( Chain: A, B)
    Structure Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 9.3e-766815View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.3e-766815View alignment
    2YI0 ( Chain: A)
    Structural Characterization Of 5-Aryl-4-(5-Substituted-2-4- Dihydroxyphenyl)-1,2,3-Thiadiazole Hsp90 Inhibitors.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-756916View alignmentSCOP
    MMDB
    CATH
    2YI5 ( Chain: A)
    Structural Characterization Of 5-Aryl-4-(5-Substituted-2-4- Dihydroxyphenyl)-1,2,3-Thiadiazole Hsp90 Inhibitors.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-756916View alignmentSCOP
    MMDB
    CATH
    2YI6 ( Chain: A)
    Structural Characterization Of 5-Aryl-4-(5-Substituted-2- 4-Dihydroxyphenyl)-1,2,3-Thiadiazole Hsp90 Inhibitors.
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-756916View alignmentSCOP
    MMDB
    CATH
    2YI7 ( Chain: A)
    Structural Characterization Of 5-Aryl-4-(5-Substituted-2-4- Dihydroxyphenyl)-1,2,3-Thiadiazole Hsp90 Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.1e-756916View alignmentSCOP
    MMDB
    CATH
    1UYM ( Chain: A)
    Human Hsp90-Beta With Pu3 (9-Butyl-8(3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine)
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.5e-757114View alignmentSCOP
    MMDB
    CATH
    3EKO ( Chain: A, B)
    Dihydroxylphenyl Amides As Inhibitors Of The Hsp90 Molecular Chaperone
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-757015View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-757015View alignment
    3K99 ( Chain: D, A, B, C)
    Hsp90 N-Terminal Domain In Complex With 4-(1,3-Dihydro-2h- Isoindol-2-Ylcarbonyl)benzene-1,3-Diol
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain D = 2.4e-757015View alignmentSCOP
    MMDB
    CATH
    Chain A = 2.4e-757015View alignment
    Chain B = 2.4e-757015View alignment
    Chain C = 2.4e-757015View alignment
    3EKR ( Chain: A, B)
    Dihydroxylphenyl Amides As Inhibitors Of The Hsp90 Molecular Chaperone
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-757015View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-757015View alignment
    3HEK ( Chain: A, B)
    Hsp90 N-Terminal Domain In Complex With 1-{4-[(2r)-1-(5- Chloro-2,4-Dihydroxybenzoyl)pyrrolidin-2-Yl]benzyl}-3,3- Difluoropyrrolidinium
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-757015View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-757015View alignment
    3R4N ( Chain: A, B)
    Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4- Fluoro-1h-Pyrazol-1-Yl)ethoxy]-6-Methylphenyl}-N-(2,2- Difluoropropyl)-5,7-Dihydro-6h-Pyrrolo[3,4-D]pyrimidine-6-Carboxamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-757015View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-757015View alignment
    3R4O ( Chain: A, B)
    Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4- Fluoro-1h-Pyrazol-1-Yl)ethoxy]-6-Methylphenyl}-N-(2,2- Difluoropropyl)-5,7-Dihydro-6h-Pyrrolo[3,4-D]pyrimidine-6-Carboxamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-757015View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-757015View alignment
    3R4P ( Chain: A, B)
    Optimization Of Potent, Selective, And Orally Bioavailable Pyrrolodinopyrimidine-Containing Inhibitors Of Heat Shock Protein 90. Identification Of Development Candidate 2-Amino-4-{4-Chloro-2-[2-(4- Fluoro-1h-Pyrazol-1-Yl)ethoxy]-6-Methylphenyl}-N-(2,2- Difluoropropyl)-5,7-Dihydro-6h-Pyrrolo[3,4-D]pyrimidine-6-Carboxamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-757015View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-757015View alignment
    3RLP ( Chain: A, B)
    Co-Crystal Structure Of The Hsp90 Atp Binding Domain In Complex With 4-(2,4-Dichloro-5-Methoxyphenyl)-6-Methylpyrimidin-2-Amine
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-757015View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-757015View alignment
    3RLQ ( Chain: A, B)
    Co-Crystal Structure Of The Hsp90 Atp Binding Domain In Complex With 4-(2,4-Dichloro-5-Methoxyphenyl)-2-Methyl-7h-Pyrrolo[2,3- D]pyrimidine-5- Carbonitrile
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-757015View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-757015View alignment
    3RLR ( Chain: A, B)
    Co-Crystal Structure Of The Hsp90 Atp Binding Domain In Complex With 4-(2,4-Dichloro-5-Methoxyphenyl)-2,6-Dimethyl-7h-Pyrrolo[2,3- D]pyrimidine-5-Carbonitrile
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-757015View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-757015View alignment
    3K98 ( Chain: A, B)
    Hsp90 N-Terminal Domain In Complex With (1r)-2-(5-Chloro-2, 4-Dihydroxybenzoyl)-N-Ethylisoindoline-1-Carboxamide
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 2.4e-757015View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-757015View alignment
    2XCM ( Chain: A, B)
    Complex Of Hsp90 N-Terminal, Sgt1 Cs And Rar1 Chord2 Domain
  • PDB_Info
  • PDB_Structure
  • Hordeum vulgareChain A = 5.2e-757016View alignmentSCOP
    MMDB
    CATH
    Chain B = 5.2e-757016View alignment
    3HHU ( Chain: A, B)
    Human Heat-Shock Protein 90 (Hsp90) In Complex With {4-[3- (2,4-Dihydroxy-5-Isopropyl-Phenyl)-5-Thioxo- 1,5-Dihydro- [1,2,4]triazol-4-Yl]-Benzyl}-Carbamic Acid Ethyl Ester {zk 2819}
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 3.6e-747015View alignmentSCOP
    MMDB
    CATH
    Chain B = 3.6e-747015View alignment
    3TUH ( Chain: B, A)
    Crystal Structure Of The N-Terminal Domain Of An Hsp90 In The Presence Of An The Inhibitor Ganetespib
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain B = 3.6e-747015View alignmentSCOP
    MMDB
    CATH
    Chain A = 3.6e-747015View alignment
    2XDU ( Chain: A)
    Structure Of Hsp90 With Small Molecule Inhibitor Bound
  • PDB_Info
  • PDB_Structure
  • Homo sapiens3.6e-747015View alignmentSCOP
    MMDB
    CATH
    2QFO ( Chain: A, B)
    Hsp90 Complexed With A143571 And A516383
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 9.5e-747015View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.5e-747015View alignment
    1OSF ( Chain: A)
    Human Hsp90 In Complex With 17-desmethoxy-17-n,n- Dimethylaminoethylamino-geldanamycin
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.5e-747015View alignmentSCOP
    MMDB
    CATH
    2QG0 ( Chain: A, B)
    Hsp90 Complexed With A943037
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 9.5e-747015View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.5e-747015View alignment
    2JJC ( Chain: A)
    Hsp90 Alpha Atpase Domain With Bound Small Molecule Fragment
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.5e-747015View alignmentSCOP
    MMDB
    CATH
    2YJW ( Chain: A)
    Tricyclic Series Of Hsp90 Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.5e-747015View alignmentSCOP
    MMDB
    CATH
    2YJX ( Chain: A)
    Tricyclic Series Of Hsp90 Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.5e-747015View alignmentSCOP
    MMDB
    CATH
    2YK2 ( Chain: A)
    Tricyclic Series Of Hsp90 Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.5e-747015View alignmentSCOP
    MMDB
    CATH
    2YKB ( Chain: A)
    Tricyclic Series Of Hsp90 Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.5e-747015View alignmentSCOP
    MMDB
    CATH
    2YKC ( Chain: A)
    Tricyclic Series Of Hsp90 Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.5e-747015View alignmentSCOP
    MMDB
    CATH
    2YKE ( Chain: A)
    Tricyclic Series Of Hsp90 Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.5e-747015View alignmentSCOP
    MMDB
    CATH
    2YKI ( Chain: A)
    Tricyclic Series Of Hsp90 Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.5e-747015View alignmentSCOP
    MMDB
    CATH
    2YKJ ( Chain: A)
    Tricyclic Series Of Hsp90 Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.5e-747015View alignmentSCOP
    MMDB
    CATH
    2YK9 ( Chain: A)
    Tricyclic Series Of Hsp90 Inhibitors
  • PDB_Info
  • PDB_Structure
  • Homo sapiens9.5e-747015View alignmentSCOP
    MMDB
    CATH
    2QF6 ( Chain: A, B, D, C)
    Hsp90 Complexed With A56322
  • PDB_Info
  • PDB_Structure
  • Homo sapiensChain A = 1.2e-737014View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.2e-737014View alignment
    Chain D = 1.2e-737014View alignment
    Chain C = 1.2e-737014View alignment
    2K5B ( Chain: A)
    Human Cdc37-Hsp90 Docking Model Based On Nmr
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.2e-737014View alignmentSCOP
    MMDB
    CATH
    3OWD ( Chain: A)
    Crystal Structure Of Hsp90 With N-Aryl-Benzimidazolone Ii
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.2e-737014View alignmentSCOP
    MMDB
    CATH
    3OWB ( Chain: A)
    Crystal Structure Of Hsp90 With Ver-49009
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.2e-737014View alignmentSCOP
    MMDB
    CATH
    3OW6 ( Chain: A)
    Crystal Structure Of Hsp90 With N-Aryl-Benzimidazolone I
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.2e-737014View alignmentSCOP
    MMDB
    CATH
    2QG2 ( Chain: A)
    Hsp90 Complexed With A917985
  • PDB_Info
  • PDB_Structure
  • Homo sapiens1.2e-737014View alignmentSCOP
    MMDB
    CATH
    3Q5L ( Chain: D, C, B, A)
    Crystal Structure Of The Amino-Terminal Domain Of Hsp90 From Leishmania Major, Lmjf33.0312:m1-K 213 In The Presence Of 17-Aep- Geldanamycin
  • PDB_Info
  • PDB_Structure
  • Leishmania majorChain D = 1.5e-736813View alignmentSCOP
    MMDB
    CATH
    Chain C = 1.5e-736813View alignment
    Chain B = 1.5e-736813View alignment
    Chain A = 1.5e-736813View alignment
    3Q5K ( Chain: A)
    Crystal Structure Of The Amino-Terminal Domain Of Hsp90 From Leishmania Major, Lmjf33.0312:m1-K213 In The Presence Of An Inhibitor
  • PDB_Info
  • PDB_Structure
  • Leishmania major1.5e-736813View alignmentSCOP
    MMDB
    CATH
    3Q5J ( Chain: A)
    Crystal Structure Of The Amino-Terminal Domain Of Hsp90 From Leishmania Major, Lmjf33.0312:m1-K213 In The Presence Of 17-Dmap- Geldanamycin
  • PDB_Info
  • PDB_Structure
  • Leishmania major1.5e-736813View alignmentSCOP
    MMDB
    CATH
    3H80 ( Chain: A)
    Crystal Structure Of The Amino-Terminal Domain Of Hsp90 From Leishmania Major, Lmjf33.0312:m1-K213
  • PDB_Info
  • PDB_Structure
  • Leishmania major strain Friedlin1.5e-736813View alignmentSCOP
    MMDB
    CATH
    3U67 ( Chain: A)
    Crystal Structure Of The N-Terminal Domain Of Hsp90 From Leishmania Major(Lmjf33.0312)in Complex With Adp
  • PDB_Info
  • PDB_Structure
  • Leishmania major strain Friedlin1.5e-736813View alignmentSCOP
    MMDB
    CATH
    3O6O ( Chain: A, B)
    Crystal Structure Of The N-Terminal Domain Of An Hsp90 From Trypanosoma Brucei, Tb10.26.1080 In The Presence Of An The Inhibitor Biib021
  • PDB_Info
  • PDB_Structure
  • Trypanosoma bruceiChain A = 2.4e-706713View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-706713View alignment
    3OPD ( Chain: A, B, C)
    Crystal Structure Of The N-Terminal Domain Of An Hsp90 From Trypanosoma Brucei, Tb10.26.1080 In The Presence Of A Benzamide Derivative
  • PDB_Info
  • PDB_Structure
  • Trypanosoma brucei bruceiChain A = 2.4e-706713View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-706713View alignment
    Chain C = 2.4e-706713View alignment
    3OMU ( Chain: A, B)
    Crystal Structure Of The N-Terminal Domain Of An Hsp90 From Trypanosoma Brucei, Tb10.26.1080 In The Presence Of A Thienopyrimidine Derivative
  • PDB_Info
  • PDB_Structure
  • Trypanosoma bruceiChain A = 2.4e-706713View alignmentSCOP
    MMDB
    CATH
    Chain B = 2.4e-706713View alignment
    1QY8 ( Chain: A)
    Crystal Structure Of The N-domain Of The Er Hsp90 Chaperone Grp94 In Complex With Radicicol
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiaris2.2e-635117View alignmentSCOP
    MMDB
    CATH
    1QY5 ( Chain: A)
    Crystal Structure Of The N-Domain Of The Er Hsp90 Chaperone Grp94 In Complex With The Specific Ligand Neca
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiaris2.2e-635117View alignmentSCOP
    MMDB
    CATH
    1U0Y ( Chain: A)
    N-Domain Of Grp94, With The Charged Domain, In Complex With The Novel Ligand N-Propyl Carboxyamido Adenosine
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiaris2.2e-635117View alignmentSCOP
    MMDB
    CATH
    1YT2 ( Chain: A)
    Crystal Structure Of The Unliganded Form Of Grp94, The Er Hsp90: Basis For Nucleotide-Induced Conformational Change, Grp94n Apo Crystal
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiaris2.2e-635117View alignmentSCOP
    MMDB
    CATH
    1QYE ( Chain: A)
    Crystal Structure Of The N-domain Of The Er Hsp90 Chaperone Grp94 In Complex With 2-chlorodideoxyadenosine
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiaris2.2e-635117View alignmentSCOP
    MMDB
    CATH
    4NH9 ( Chain: A)
    Correlation Between Chemotype-dependent Binding Conformations Of Hsp90 Alpha/beta And Isoform Selectivity
  • PDB_Info
  • PDB_Structure
  • Homo sapiens4.8e-635117View alignmentSCOP
    MMDB
    CATH
    3PEH ( Chain: B, A)
    Crystal Structure Of The N-Terminal Domain Of An Hsp90 From Plasmodium Falciparum, Pfl1070c In The Presence Of A Thienopyrimidine Derivative
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparum 3D7Chain B = 1.2e-594921View alignmentSCOP
    MMDB
    CATH
    Chain A = 1.2e-594921View alignment
    3PEJ ( Chain: A, B)
    Crystal Structure Of The N-Terminal Domain Of An Hsp90 From Plasmodium Falciparum, Pfl1070c In The Presence Of Macbecin
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparum 3D7Chain A = 1.2e-594921View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.2e-594921View alignment
    2GQ0 ( Chain: A, B)
    Crystal Structure Of The Middle Domain Of Htpg, The E. Coli Hsp90
  • PDB_Info
  • PDB_Structure
  • Escherichia coliChain A = 1.2e-574523View alignmentSCOP
    MMDB
    CATH
    Chain B = 1.2e-574523View alignment
    1Y6Z ( Chain: B, A)
    Middle Domain Of Plasmodium Falciparum Putative Heat Shock Protein Pf14_0417
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparum 3D7Chain B = 6.3e-544125View alignmentSCOP
    MMDB
    CATH
    Chain A = 6.3e-544125View alignment
    3O2F ( Chain: B, A)
    Structure Of The N-domain Of Grp94 Bound To The Hsp90 Inhibitor Pu-h54
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain B = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain A = 9.4e-515118View alignment
    2HG1 ( Chain: B, A)
    N-Domain Of Grp94 In Complex With The Novel Ligand N-(2- Hydroxyl)ethyl Carboxyamido Adenosine
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain B = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain A = 9.4e-515118View alignment
    2H8M ( Chain: B, A)
    N-Domain Of Grp94 In Complex With The 2-Iodo-Neca
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain B = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain A = 9.4e-515118View alignment
    2HCH ( Chain: B, A)
    N-Domain Of Grp94 In Complex With The Novel Ligand N-(2- Amino)ethyl Carboxyamido Adenosine
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain B = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain A = 9.4e-515118View alignment
    2GQP ( Chain: A, B)
    N-Domain Of Grp94 In Complex With The Novel Ligand N-Propyl Carboxyamido Adenosine
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain A = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.4e-515118View alignment
    2GFD ( Chain: B, A)
    Grp94 In Complex With The Novel Hsp90 Inhibitor Radamide
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain B = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain A = 9.4e-515118View alignment
    1U2O ( Chain: A, B)
    Crystal Structure Of The N-Domain Of Grp94 Lacking The Charged Domain In Complex With Neca
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain A = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.4e-515118View alignment
    1TBW ( Chain: A, B)
    Ligand Induced Conformational Shift In The N-Terminal Domain Of Grp94, Open Conformation
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain A = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.4e-515118View alignment
    1TC0 ( Chain: A, B)
    Ligand Induced Conformational Shifts In The N-Terminal Domain Of Grp94, Open Conformation Complexed With The Physiological Partner Atp
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain A = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.4e-515118View alignment
    1TC6 ( Chain: A, B)
    Ligand Induced Conformational Shift In The N-Terminal Domain Of Grp94, Open Conformation Adp-Complex
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain A = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.4e-515118View alignment
    1U0Z ( Chain: A, B)
    N-Domain Of Grp94 Lacking The Charged Domain In Complex With Radicicol
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain A = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.4e-515118View alignment
    1YSZ ( Chain: A)
    Crystal Structure Of The Unliganded Form Of Grp94, The Er Hsp90: Basis For Nucleotide-Induced Conformational Change, Grp94n(Delta)41 Apo Crystal Soaked With Neca
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiaris9.4e-515118View alignmentSCOP
    MMDB
    CATH
    1YT0 ( Chain: A)
    Crystal Structure Of The Unliganded Form Of Grp94, The Er Hsp90: Basis For Nucleotide-Induced Conformational Change, Grp94n(Delta)41 Apo Crystal Soaked With Adp
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiaris9.4e-515118View alignmentSCOP
    MMDB
    CATH
    1YT1 ( Chain: A, B)
    Crystal Structure Of The Unliganded Form Of Grp94, The Er Hsp90: Basis For Nucleotide-Induced Conformational Change, Grp94n(Delta)41 Apo Crystal
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain A = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.4e-515118View alignment
    2EXL ( Chain: A, B)
    Grp94 N-Terminal Domain Bound To Geldanamycin
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain A = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.4e-515118View alignment
    2FYP ( Chain: A, B)
    Grp94 In Complex With The Novel Hsp90 Inhibitor Radester Amine
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiarisChain A = 9.4e-515118View alignmentSCOP
    MMDB
    CATH
    Chain B = 9.4e-515118View alignment
    2ESA ( Chain: A)
    Grp94 N-Terminal Domain Bound To Geldanamycin: Effects Of Mutants 168- 169 Ks-Aa
  • PDB_Info
  • PDB_Structure
  • Canis lupus familiaris8.6e-505019View alignmentSCOP
    MMDB
    CATH
    2IOR ( Chain: A)
    Crystal Structure Of The N-Terminal Domain Of Htpg, The Escherichia Coli Hsp90, Bound To Adp
  • PDB_Info
  • PDB_Structure
  • Escherichia coli9.9e-454625View alignmentSCOP
    MMDB
    CATH
    3IED ( Chain: A)
    Crystal Structure Of N-Terminal Domain Of Plasmodium Falciparum Hsp90 (Pf14_0417) In Complex With Amppn
  • PDB_Info
  • PDB_Structure
  • Plasmodium falciparum 3D76.7e-404320View alignmentSCOP
    MMDB
    CATH
    2WN6 ( Chain: A)
    Structural Basis For Substrate Recognition In The Enzymatic Component Of Adp-Ribosyltransferase Toxin Cdta From Clostridium Difficile
  • PDB_Info
  • PDB_Structure
  • Peptoclostridium difficile4.0e-062518View alignmentSCOP
    MMDB
    CATH
    2WN8 ( Chain: A)
    Structural Basis For Substrate Recognition In The Enzymatic Component Of Adp-Ribosyltransferase Toxin Cdta From Clostridium Difficile
  • PDB_Info
  • PDB_Structure
  • Peptoclostridium difficile8.7e-062419View alignmentSCOP
    MMDB
    CATH
    2WN7 ( Chain: A)
    Structural Basis For Substrate Recognition In The Enzymatic Component Of Adp-Ribosyltransferase Toxin Cdta From Clostridium Difficile
  • PDB_Info
  • PDB_Structure
  • Peptoclostridium difficile8.7e-062419View alignmentSCOP
    MMDB
    CATH
    2WN5 ( Chain: A)
    Structural Basis For Substrate Recognition In The Enzymatic Component Of Adp-Ribosyltransferase Toxin Cdta From Clostridium Difficile
  • PDB_Info
  • PDB_Structure
  • Peptoclostridium difficile8.7e-062419View alignmentSCOP
    MMDB
    CATH
    2WN4 ( Chain: A)
    Structural Basis For Substrate Recognition In The Enzymatic Component Of Adp-Ribosyltransferase Toxin Cdta From Clostridium Difficile
  • PDB_Info
  • PDB_Structure
  • Peptoclostridium difficile8.7e-062419View alignmentSCOP
    MMDB
    CATH
    1SF8 ( Chain: G, F, E, D, C, B, H, A)
    Crystal Structure Of The Carboxy-terminal Domain Of Htpg, The E. Coli Hsp90
  • PDB_Info
  • PDB_Structure
  • Escherichia coliChain G = 0.0001392620View alignmentSCOP
    MMDB
    CATH
    Chain F = 0.0001392620View alignment
    Chain E = 0.0001392620View alignment
    Chain D = 0.0001392620View alignment
    Chain C = 0.0001392620View alignment
    Chain B = 0.0001392620View alignment
    Chain H = 0.0001392620View alignment
    Chain A = 0.0001392620View alignment

    Last updated on 2014-06-05